Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Speranta AVRAM"'
Autor:
Ana Maria Udrea, Angela Staicu, Adriana Smarandache, Ionut Relu Andrei, Madalina Andreea Badea, Speranta Avram, Mihail Lucian Pascu, Ruxandra Angela Pirvulescu, Mihaela Balas
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Breast cancer remains a global health challenge, prompting interest in the anticancer properties of other drugs, including chlorpromazine (CPZ). This study presents a novel approach in breast cancer treatment using laser irradiated CPZ. CPZ
Externí odkaz:
https://doaj.org/article/2da2e62ee36047a89f20c8cc061a562e
Publikováno v:
Applied Medical Informatics, Vol 46, Iss Suppl. S1, Pp S29-S29 (2024)
Industrialization and urban expansion have accelerated pollution from human activities, including the release of polycyclic aromatic hydrocarbons (PAHs), which pose significant environmental and health risks. This study aims to computationally assess
Externí odkaz:
https://doaj.org/article/a5e14e86793d48d98549f05f58b99dac
Autor:
Florentina Monica Raduly, Valentin Raditoiu, Alina Raditoiu, Cristian Andi Nicolae, Maria Grapin, Miruna Silvia Stan, Ionela Cristina Voinea, Raluca-Ioana Vlasceanu, Cristina Doina Nitu, Dan F. Mihailescu, Speranta Avram, Maria Mernea
Publikováno v:
Gels, Vol 10, Iss 6, p 376 (2024)
The therapeutic effects of curcumin and its derivatives, based on research in recent years, are limited by their low bioavailability. To improve bioavailability and develop the medical field of application, different delivery systems have been develo
Externí odkaz:
https://doaj.org/article/1f227d7264844281a5284e80e8bcc3c4
Autor:
Florea Dumitrascu, Mino R. Caira, Speranta Avram, Catalin Buiu, Ana Maria Udrea, Ilinca Margareta Vlad, Irina Zarafu, Petre Ioniță, Diana Camelia Nuță, Marcela Popa, Mariana-Carmen Chifiriuc, Carmen Limban
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
IntroductionOne of the promising leads for the rapid discovery of alternative antimicrobial agents is to repurpose other drugs, such as nonsteroidal anti-inflammatory agents (NSAIDs) for fighting bacterial infections and antimicrobial resistance.Meth
Externí odkaz:
https://doaj.org/article/32fc50fa862e442ea44e4b46ea347e41
Autor:
Maria Coanda, Carmen Limban, Constantin Draghici, Anne-Marie Ciobanu, Georgiana Alexandra Grigore, Marcela Popa, Miruna Stan, Cristina Larion, Speranta Avram, Catalina Mares, Mariana-Catalina Ciornei, Aura Dabu, Ariana Hudita, Bianca Galateanu, Lucia Pintilie, Diana Camelia Nuta
Publikováno v:
Pharmaceuticals, Vol 17, Iss 4, p 405 (2024)
Growing resistance to antimicrobials, combined with pathogens that form biofilms, presents significant challenges in healthcare. Modifying current antimicrobial agents is an economical approach to developing novel molecules that could exhibit biologi
Externí odkaz:
https://doaj.org/article/edda1d07c57e4e1ba6d89b721387101b
Autor:
Ilinca Margareta Vlad, Diana Camelia Nuță, Miron Theodor Căproiu, Florea Dumitrașcu, Eleonóra Kapronczai, Georgiana Ramona Mük, Speranta Avram, Adelina Gabriela Niculescu, Irina Zarafu, Vanesa Alexandra Ciorobescu, Ana Maria Brezeanu, Carmen Limban
Publikováno v:
Antibiotics, Vol 13, Iss 3, p 212 (2024)
N-acyl hydrazone (NAH) is recognized as a promising framework in drug design due to its versatility, straightforward synthesis, and attractive range of biological activities, including antimicrobial, antitumoral, analgesic, and anti-inflammatory prop
Externí odkaz:
https://doaj.org/article/5a5480f5373e44d68bd0e545ee717d3f
Autor:
Cristina Doina Niţu, Maria Mernea, Raluca Ioana Vlasceanu, Bianca Voicu-Balasea, Madalina Andreea Badea, Florentina Monica Raduly, Valentin Rădiţoiu, Alina Rădiţoiu, Speranta Avram, Dan F. Mihailescu, Ionela C. Voinea, Miruna Silvia Stan
Publikováno v:
Pharmaceutics, Vol 16, Iss 2, p 205 (2024)
Curcumin is a polyphenol of the Curcuma longa plant, which can be used for various medicinal purposes, such as inflammation and cancer treatment. In this context, two symmetric curcumin derivatives (D1—(1E,6E)-1,7-bis(4-acetamidophenyl)hepta-1,6-di
Externí odkaz:
https://doaj.org/article/b9849885c27440128f2c1c84122a447c
Autor:
Ana Maria Udrea, Adriana Smarandache, Andra Dinache, Catalina Mares, Simona Nistorescu, Speranta Avram, Angela Staicu
Publikováno v:
Pharmaceutics, Vol 15, Iss 8, p 2124 (2023)
Malignant melanoma poses a significant global health burden. It is the most aggressive and lethal form of skin cancer, attributed to various risk factors such as UV radiation exposure, genetic modifications, chemical carcinogens, immunosuppression, a
Externí odkaz:
https://doaj.org/article/adb41a6ff5e346778ab11f74da8a3d98
Autor:
Maria Mernea, Maria-Eliza Satmaru, Alina-Nicoleta Toma, Cristina Doina Niţu, Dan Florin Mihailescu, Speranta Avram, Miruna-Silvia Stan
Publikováno v:
Medical Sciences Forum, Vol 14, Iss 1, p 103 (2022)
Anxiety and depression are two conditions that had increased incidences in the context of COVID-19. The administration of current therapies based on anxiolytic and antidepressant drugs can result in adverse reactions and even potential dangers in the
Externí odkaz:
https://doaj.org/article/fa320f32b2cd4650aa2006cbc5c73424
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2390 (2022)
Photodynamic therapy has the potential to be a new and effective cancer treatment. Even if in vitro and in vivo research show promise, the molecular mechanism remains unclear. In this study, molecular docking simulations predict the binding affinity
Externí odkaz:
https://doaj.org/article/3052f8aef6fc40768214367c3b95e5e7