Zobrazeno 1 - 10 of 17 pro vyhledávání: '"Spenser S. Smith"'
1
Akademický článek
Stable integration of an optimized inducible promoter system enables spatiotemporal control of gene expression throughout avian development
Autor: Daniel Chu, An Nguyen, Spenser S. Smith, Zuzana Vavrušová, Richard A. Schneider
Publikováno v: Biology Open, Vol 9, Iss 10 (2020)
Precisely altering gene expression is critical for understanding molecular processes of embryogenesis. Although some tools exist for transgene misexpression in developing chick embryos, we have refined and advanced them by simplifying and optimizing
Externí odkaz: https://doaj.org/article/54876af4d9bb4ec2a386766412cbb38f
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2
Akademický článek
Species-specific sensitivity to TGFβ signaling and changes to the Mmp13 promoter underlie avian jaw development and evolution
Autor: Spenser S Smith, Daniel Chu, Tiange Qu, Jessye A Aggleton, Richard A Schneider
Publikováno v: eLife, Vol 11 (2022)
Precise developmental control of jaw length is critical for survival, but underlying molecular mechanisms remain poorly understood. The jaw skeleton arises from neural crest mesenchyme (NCM), and we previously demonstrated that these progenitor cells
Externí odkaz: https://doaj.org/article/fcf6e80aa9b54a54804a4059c0d003b5
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4
Species-specific deployment of Runx2 isoforms and differential regulation of target genes during avian jaw development and evolution
Autor: Richard A. Schneider, Krish G, Daniel Chu, Lucena Aj, Qu T, Huang T, Spenser S. Smith
Developmental regulation of bone formation in the jaw skeleton is essential to species-specific adaptation. The jaws are derived from neural crest mesenchyme (NCM), a progenitor population that directs skeletal patterning by exerting temporal and spa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::26eeb0b21cd054aa50862bd091cf0644
https://doi.org/10.1101/2021.05.25.444052
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6
miR-433-3p suppresses bone formation and mRNAs critical for osteoblast function in mice
Autor: Spenser S. Smith, Daniel W. Youngstrom, Henry H. Hrdlicka, Hicham Drissi, John Garcia, Sangita Karki, Anne M. Delany
Publikováno v: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral ResearchREFERENCES. 36(9)
MicroRNAs (miRNAs) are key posttranscriptional regulators of osteoblastic commitment and differentiation. miR-433-3p was previously shown to target Runt-related transcription factor 2 (Runx2) and to be repressed by bone morphogenetic protein (BMP) si
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e62394420ccdf2eb2b5241563f554b92
https://pubmed.ncbi.nlm.nih.gov/34004029
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7
Species-specific sensitivity to TGFβ signaling and changes to the Mmp13 promoter underlie avian jaw development and evolution
Autor: Richard A. Schneider, Daniel Chu, Spenser S. Smith, Tiange Qu
Developmental control of jaw length is critical for survival. The jaw skeleton arises from neural crest mesenchyme and previously we demonstrated that these progenitors upregulate bone-resorbing enzymes includingMatrix metalloproteinase 13(Mmp13)when
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::36401ca2e3338fd4e446e1cee52f0e34
https://doi.org/10.1101/2020.12.23.424223
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8
Species-specific sensitivity to TGFβ signaling and changes to the Mmp13 promoter underlie avian jaw development and evolution
Autor: Spenser S Smith, Daniel Chu, Tiange Qu, Jessye A Aggleton, Richard A Schneider
Publikováno v: eLife. 11
Precise developmental control of jaw length is critical for survival, but underlying molecular mechanisms remain poorly understood. The jaw skeleton arises from neural crest mesenchyme (NCM), and we previously demonstrated that these progenitor cells
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6c09fc452906379c7c13945c15eb04e
https://pubmed.ncbi.nlm.nih.gov/35666955
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9
Stable integration of an optimized inducible promoter system enables spatiotemporal control of gene expression throughout avian development
Autor: Spenser S. Smith, Richard A. Schneider, An Nguyen, Daniel Chu, Zuzana Vavrusova
Publikováno v: Biology Open
article-version (VoR) Version of Record
Biology Open, Vol 9, Iss 10 (2020)
Biology open, vol 9, iss 10
Precisely altering gene expression is critical for understanding molecular processes of embryogenesis. Although some tools exist for transgene misexpression in developing chick embryos, we have refined and advanced them by simplifying and optimizing
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bd13071ede79f75fab45ae91ad38772
http://europepmc.org/articles/PMC7561481
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10
Connective Tissue Growth Factor reporter mice label a subpopulation of mesenchymal progenitor cells that reside in the trabecular bone region
Autor: Peter Maye, Wen Wang, Fayekah Assanah, Yaling Liu, Sara Strecker, Liping Wang, Spenser S. Smith
Publikováno v: Bone. 71:76-88
Few gene markers selectively identify mesenchymal progenitor cells inside the bone marrow. We have investigated a cell population located in the mouse bone marrow labeled by Connective Tissue Growth Factor reporter expression (CTGF-EGFP). Bone marrow
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afe974b8204513702386ca498effe53d
https://doi.org/10.1016/j.bone.2014.10.005
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