Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Spencer W. Green"'
Publikováno v:
British Journal of Haematology. 125:383-391
Summary Paroxysmal nocturnal haemoglobinuria (PNH) results from acquired mutations in the PIG-A gene of an haematopoietic stem cell, leading to defective biosynthesis of glycosylphosphatidylinositol (GPI) anchors and deficient expression of GPI-ancho
Publikováno v:
Virology. 210(2):283-291
Goose parvovirus is the etiological agent of Derzsy's disease, a fatal hepatitis of young geese. The virus infects geese and Muscovy ducks and can be propagated in the laboratory in primary embryonic goose fibroblasts. To date the virus has only been
Publikováno v:
British Journal of Haematology. 88:895-898
Upstream sequences within the terminal hairpin positively regulate the P6 promoter of B19 parvovirus
Autor:
Hao Yu-Shu, Takashi Shimada, Kevin T. McDonagh, Neal S. Young, Spencer W. Green, Johnson M. Liu
Publikováno v:
Virology. 185:39-47
For the 1319 parvovirus P6 promoter, a 96-nt minimal truncation mutant retained activity in transient reporter gene assays. Deletion of sequences further upstream from this minimal promoter markedly diminished reporter activity in certain cell lines.
Autor:
Elena E. Solomou, Spencer W. Green, Federica Gibellini, Daniela Malide, Richard W. Childs, Maria Berg, Stephen J. Chanock, Valeria Visconte, Neal S. Young, Brian J. Stewart
Perforin is a cytolytic protein expressed mainly in activated cytotoxic T lymphocytes (CTL) and natural killer (NK) cells. In T and NK cells perforin is stored in cytoplasmic granules and is essential for killing via non-Fas-mediated mechanisms. Perf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::141966431bead04a895ab5b760603fad
https://europepmc.org/articles/PMC1890825/
https://europepmc.org/articles/PMC1890825/
Publikováno v:
Virology. 269(1)
We have previously reported the identification of a novel simian parvovirus in cynomolgus monkeys, which causes severe anemia in immunosuppressed cynomolgus monkeys and is currently being studied as an animal model for human B19 infection. We now rep
Autor:
Daniel E. Dunn, Shoichi Nagakura, Spencer W. Green, Martha Kirby, Neal S. Young, Mysore S. Anil Kumar, Stephen J. Rosenfeld, Patcharin Tanawattanacharoen, Piernicola Boccuni
Publikováno v:
Annals of internal medicine. 131(6)
Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired hematopoietic stem-cell disorder in which the affected cells are deficient in glycosylphosphatidylinositol (GPI)-anchored proteins. Paroxysmal nocturnal hemoglobinuria is frequently associated
Autor:
Kevin E. Brown, Janis L. Abkowitz, Nicholas L. Kovach, Spencer W. Green, Robert W. Wood, Neal S. Young
Publikováno v:
The Journal of infectious diseases. 176(1)
Parvovirus B19 (B19) DNA was detected by dot blot hybridization in sera from 5 (17%) of 30 human immunodeficiency virus (HIV)-infected patients with hematocrits (HCT) ofor =24 and 4 (31%) of 13 HRV-infected patients with HCT ofor =20, suggesting that
Publikováno v:
Virology. 210(2)
We recently reported the identification of a novel simian parvovirus in cynomolgus monkeys with severe anemia. We now describe the cloning and sequencing of 4986 nucleotides of the viral DNA. Like the human parvovirus B19, simian parvovirus encapsida
Autor:
Joseph A. Bellanti, J Antunez de Mayolo, Tj Smith, Spencer W. Green, Stephen D. Smith, N S Young, Kevin E. Brown
Publikováno v:
Lancet (London, England). 343(8902)
We report three children with congenital anaemia after intrauterine infection with B19 parvovirus. All the fetuses developed hydrops fetalis that was treated by blood transfusion. After delivery the infants had hypogammaglobulinaemia. In all three, s