Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Spencer T. Burton"'
Autor:
Benjamin Gaston, Laura Smith, Jürgen Bosch, James Seckler, Diana Kunze, Janna Kiselar, Nadzeya Marozkina, Craig A. Hodges, Patrick Wintrobe, Kellen McGee, Tatiana S. Morozkina, Spencer T. Burton, Tristan Lewis, Timothy Strassmaier, Paulina Getsy, James N. Bates, Stephen J. Lewis
Publikováno v:
JCI Insight, Vol 5, Iss 18 (2020)
S-nitroso-l-cysteine (L-CSNO) behaves as a ligand. Its soluble guanylate cyclase–independent (sGC-independent) effects are stereoselective — that is, not recapitulated by S-nitroso-d-cysteine (D-CSNO) — and are inhibited by chemical congeners.
Externí odkaz:
https://doaj.org/article/0d6ea0f326f84f139e9fc944a5002b14
Autor:
James M Seckler, Nikki M Meyer, Spencer T Burton, James N Bates, Benjamin Gaston, Stephen J Lewis
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0187149 (2017)
Small molecule S-nitrosothiols are a class of endogenous chemicals in the body, which have been implicated in a variety of biological functions. However, the labile nature of NO and the limits of current detection assays have made studying these mole
Externí odkaz:
https://doaj.org/article/c4ec4f213c964ba39adb53a95d6dab6c
Autor:
Diana Kunze, Nadzeya Marozkina, Patrick Wintrobe, Tatiana S Morozkina, Tristan H. Lewis, Stephen J. Lewis, James N. Bates, James M. Seckler, Benjamin Gaston, Spencer T. Burton, Craig A. Hodges, Janna Kiselar, Jürgen Bosch, Laura Smith, Paulina M. Getsy, Timothy Strassmaier, Kellen E. McGee
Publikováno v:
JCI Insight, Vol 5, Iss 18 (2020)
JCI Insight
JCI Insight
S-nitroso-l-cysteine (L-CSNO) behaves as a ligand. Its soluble guanylate cyclase–independent (sGC-independent) effects are stereoselective — that is, not recapitulated by S-nitroso-d-cysteine (D-CSNO) — and are inhibited by chemical congeners.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b2e357d384fc0d275b5c6b7647d2f2c
https://doaj.org/article/0d6ea0f326f84f139e9fc944a5002b14
https://doaj.org/article/0d6ea0f326f84f139e9fc944a5002b14
Autor:
Clare L M LeGuyader, Michael K. Gilson, Michael D. Burkart, Arnold Garcia, Nathan C. Gianneschi, Jin Yang, Paul A. Bertin, Jeremiah D. Momper, Niel M. Henriksen, Christopher V. Barback, Matt J. Jaremko, Spencer T Burton, Cassandra E. Callmann, Matthew P. Thompson, Warren C. W. Chan, Robert Hennis
Publikováno v:
Journal of the American Chemical Society
We describe the design, synthesis, and antitumor activity of an 18 carbon α,ω-dicarboxylic acid monoconjugated via an ester linkage to paclitaxel (PTX). This 1,18-octadecanedioic acid-PTX (ODDA-PTX) prodrug readily forms a noncovalent complex with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::973c7d21ae614ef3e358991a71cec33a
https://pubmed.ncbi.nlm.nih.gov/31317744
https://pubmed.ncbi.nlm.nih.gov/31317744
Autor:
Stephen J. Lewis, Spencer T. Burton, Benjamin Gaston, James N. Bates, Nikki M. Meyer, James M. Seckler
Publikováno v:
Biophysical Journal. 112:457a
Small molecule S-nitrosothiols are a class of endogenous chemicals which are produced by various forms of nitric oxide synthase. The regulation of these molecules has been shown to play a role in control of a variety of bodily processes and disease m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04a626d825d094cbf440636d31e7bcc0
https://doi.org/10.1016/j.bpj.2016.11.2451
https://doi.org/10.1016/j.bpj.2016.11.2451