Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Spencer T Brown"'
Publikováno v:
eLife, Vol 9 (2020)
Innate defensive behaviors, such as freezing, are adaptive for avoiding predation. Freezing-related midbrain regions project to the cerebellum, which is known to regulate rapid sensorimotor integration, raising the question of cerebellar contribution
Externí odkaz:
https://doaj.org/article/bf32b6b6c27e4a66baa542650d661c9f
Publikováno v:
Journal of General Physiology. 151:1300-1318
Voltage-gated Na channels of Purkinje cells are specialized to maintain high availability during high-frequency repetitive firing. They enter fast-inactivated states relatively slowly and undergo a voltage-dependent open-channel block by an intracell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5911b1eb638c4b5326118d503a2c5f29
https://doi.org/10.1085/jgp.201912390
https://doi.org/10.1085/jgp.201912390
Publikováno v:
The Journal of General Physiology
Purkinje neurons express voltage-gated Na channels and auxiliary proteins that facilitate rapid firing. White et al. find that Na current in isolated Purkinje cells is unaffected by loss of NaVβ4 subunits, but transient current is briefer and resurg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::198595f93896b727edbb65d631d24f66
https://pubmed.ncbi.nlm.nih.gov/31558566
https://pubmed.ncbi.nlm.nih.gov/31558566
Autor:
Indira M. Raman, Spencer T Brown
To test how cerebellar crus I/II Purkinje cells and their targets in the lateral cerebellar nuclei (CbN) integrate sensory and motor-related inputs and contribute to reflexive movements, we recorded extracellularly in awake, head-fixed mice during no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f708654983a2916122f78a74abb9e5be
https://europepmc.org/articles/PMC6367942/
https://europepmc.org/articles/PMC6367942/
