Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Spencer N. Wren"'
Autor:
Sarah E. Gilbertson, Hannah C. Walter, Katherine Gardner, Spencer N. Wren, Golnaz Vahedi, Amy S. Weinmann
Publikováno v:
Cell Reports, Vol 39, Iss 5, Pp 110769- (2022)
Summary: Distinguishing between conserved and divergent regulatory mechanisms is essential for translating preclinical research from mice to humans, yet there is a lack of information about how evolutionary genome rearrangements affect the regulation
Externí odkaz:
https://doaj.org/article/8360c945fffa46c4b2bc23458b227aa1
Autor:
Ornella I. Selmin, Andreas J. Papoutsis, Sabine Hazan, Christopher Smith, Nick Greenfield, Micah G. Donovan, Spencer N. Wren, Thomas C. Doetschman, Justin M. Snider, Ashley J. Snider, Sherry H.-H. Chow, Donato F. Romagnolo
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13, p 6919 (2021)
Background: Concerns are emerging that a high-fat diet rich in n-6 PUFA (n-6HFD) may alter gut microbiome and increase the risk of intestinal disorders. Research is needed to model the relationships between consumption of an n-6HFD starting at weanin
Externí odkaz:
https://doaj.org/article/36651f86dbe54089a0854884d6fabeed
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 7829 (2020)
A diet high in n-6 polyunsaturated fatty acids (PUFAs) may contribute to inflammation and tissue damage associated with obesity and pathologies of the colon and liver. One contributing factor may be dysregulation by n-6 fatty acids of enterohepatic b
Externí odkaz:
https://doaj.org/article/ba4acf31c27242cf83c3300d5bad1f8e
Publikováno v:
Br J Pharmacol
Breast cancer (BC) is the most common cancer and second leading cause of cancer mortality in women worldwide. Validated biomarkers enhance efforts for early detection and treatment, which reduce the risk of mortality. Epigenetic signatures have been
Autor:
Christopher Smith, Justin M. Snider, Thomas Doetschman, Micah G. Donovan, Donato F. Romagnolo, Sherry H.-H. Chow, Spencer N. Wren, Nick Greenfield, Andreas J. Papoutsis, Ornella I. Selmin, Ashley J. Snider, Sabine Hazan
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 13
International Journal of Molecular Sciences, Vol 22, Iss 6919, p 6919 (2021)
Volume 22
Issue 13
International Journal of Molecular Sciences, Vol 22, Iss 6919, p 6919 (2021)
Background: Concerns are emerging that a high-fat diet rich in n-6 PUFA (n-6HFD) may alter gut microbiome and increase the risk of intestinal disorders. Research is needed to model the relationships between consumption of an n-6HFD starting at weanin
Publikováno v:
International Journal of Molecular Sciences
A diet high in n-6 polyunsaturated fatty acids (PUFAs) may contribute to inflammation and tissue damage associated with obesity and pathologies of the colon and liver. One contributing factor may be dysregulation by n-6 fatty acids of enterohepatic b
Publikováno v:
Current Developments in Nutrition. 3:nzz044.P08-122
OBJECTIVES: The farnesoid-X-receptor (FXR) regulates bile acid (BA) homeostasis, protecting against colonic inflammation and cancer. Conversely, increased intestinal levels of BA and expression of cyclooxygenase-2 (COX-2) increase the risk of inflamm