Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Spencer Larkin"'
Publikováno v:
BMC Urology, Vol 20, Iss 1, Pp 1-7 (2020)
Abstract Background In patients seen in the emergency department (ED) with acute stone obstruction many risk factors that indicate need for urgent renal drainage are known. However, in patients discharged from ED without renal drainage factors that c
Externí odkaz:
https://doaj.org/article/f3eac3af944c4f31b2a5b11d0826ec55
Autor:
Spencer Larkin, Natasha Kyprianou
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 9, Pp 18421-18436 (2013)
Urologic tumors continue to represent a huge fraction of cancer cases in the United States, with over 376,310 estimated new diagnoses in 2013. As with many types of tumors, urologic tumors vary greatly in their phenotype, ranging from minimally invas
Externí odkaz:
https://doaj.org/article/647eed2ba982475db6c48959a71e2e02
Autor:
Natasha Kyprianou, Shahriar Koochekpour, Craig Horbinski, Hong Pu, Sarah K. Martin, Spencer Larkin, Beibei Zhu, Joanne Collazo
PDF file - 40KB, Constitutively inactive form of cofilin (S3DCFL) decreases prostate cancer cell migration and ECM-adhesion. Panel A, Mutation mimicking the constitutively active form of cofilin (S3ACFL) increases prostate cancer cell migration (p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39ade58a3b5affbac6c23878d72f398c
https://doi.org/10.1158/0008-5472.22401087.v1
https://doi.org/10.1158/0008-5472.22401087.v1
Autor:
Natasha Kyprianou, Shahriar Koochekpour, Craig Horbinski, Hong Pu, Sarah K. Martin, Spencer Larkin, Beibei Zhu, Joanne Collazo
PDF file - 41KB, TGF-β leads to cofilin dephsphorylation and activation (via regulating RhoA) in human LNCaP TβRII prostate cancer cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d25f13e44d83c38b46b0955144ccc4a2
https://doi.org/10.1158/0008-5472.22401090
https://doi.org/10.1158/0008-5472.22401090
Autor:
Natasha Kyprianou, Shahriar Koochekpour, Craig Horbinski, Hong Pu, Sarah K. Martin, Spencer Larkin, Beibei Zhu, Joanne Collazo
PDF file - 50KB, Effect of cofilin activation status or loss on prostate cancer cell death and invasion. Panel A, Neither a mutation on phosphorylation site (S3ACFL) nor silencing of cofilin expression (shCFL1) has a significant effect on cell viabil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e6024f30f13342db5b72cabac157230
https://doi.org/10.1158/0008-5472.22401093.v1
https://doi.org/10.1158/0008-5472.22401093.v1
Autor:
Natasha Kyprianou, Shahriar Koochekpour, Craig Horbinski, Hong Pu, Sarah K. Martin, Spencer Larkin, Beibei Zhu, Joanne Collazo
Cofilin (CFL) is an F-actin–severing protein required for the cytoskeleton reorganization and filopodia formation, which drives cell migration. CFL binding and severing of F-actin is controlled by Ser3 phosphorylation, but the contributions of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93c866b8f6a4611cce783a774830d0a7
https://doi.org/10.1158/0008-5472.c.6505755
https://doi.org/10.1158/0008-5472.c.6505755
Autor:
Natasha Kyprianou, Shahriar Koochekpour, Craig Horbinski, Hong Pu, Sarah K. Martin, Spencer Larkin, Beibei Zhu, Joanne Collazo
PDF file - 77KB, Characterization of human prostate cancer associated fibroblasts (CAFs). Panel A, We generated five distinct primary cultures of human prostate cancer associated fibroblasts from prostatectomy specimens. Western blot of CAFs, PCa-Str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::655bc33e1aa753f753c244eac7a8c47f
https://doi.org/10.1158/0008-5472.22401084
https://doi.org/10.1158/0008-5472.22401084
Autor:
Natasha Kyprianou, Shahriar Koochekpour, Craig Horbinski, Hong Pu, Sarah K. Martin, Spencer Larkin, Beibei Zhu, Joanne Collazo
PDF file - 108KB, Evaluation of protein immunoreactivity in human prostate cancer tissue sections. Cofilin expression scoring scale from 0 (absence of immunostaining) to +3 (high expression). Magnification X100.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a542c7e4015f533c6ad45a87c54ac85
https://doi.org/10.1158/0008-5472.22401081.v1
https://doi.org/10.1158/0008-5472.22401081.v1
Publikováno v:
BMC Urology, Vol 20, Iss 1, Pp 1-7 (2020)
BMC Urology
BMC Urology
Background In patients seen in the emergency department (ED) with acute stone obstruction many risk factors that indicate need for urgent renal drainage are known. However, in patients discharged from ED without renal drainage factors that can minimi
Autor:
Spencer Larkin, David Preston
Publikováno v:
Urology Practice. 2:106-108
Introduction Ureteral stent placement is the main treatment for ureteral obstruction in contemporary urological practice. Meticulous followup is required to confirm ureteral stent removal. Forgotten ureteral stents create significant patient and phys