Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Spencer L. Smith"'
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Imaging of neuronal activity across distant brain regions is challenging. Here, the authors introduce a two-photon microscope with two independently controlled scan engines, and demonstrate calcium imaging with subcellular resolution in brain regions
Externí odkaz:
https://doaj.org/article/61e2b203f08348f7bc349521ead6e6c7
Autor:
Mitchell Clough, Ichun Anderson Chen, Seong-Wook Park, Allison M. Ahrens, Jeffrey N. Stirman, Spencer L. Smith, Jerry L. Chen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
Functional brain imaging with two-photon microscopy is limited by a tradeoff between imaging area and acquisition speed. Here, the authors present Quadroscope, a flexible microscope which allows for simultaneous video rate acquisition of four indepen
Externí odkaz:
https://doaj.org/article/b981c71532914106a9b1e5778371edc0
Autor:
Leah B. Townsend, Kelly A. Jones, Christopher R. Dorsett, Benjamin D. Philpot, Spencer L. Smith
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 12, Iss 1, Pp 1-14 (2020)
Abstract Background Sensory processing deficits are common in individuals with neurodevelopmental disorders. One hypothesis is that deficits may be more detectable in downstream, “higher” sensory areas. A mouse model of Angelman syndrome (AS), wh
Externí odkaz:
https://doaj.org/article/c228e2076f6a4eaca4362e477f72d151
Publikováno v:
Mathematics, Vol 9, Iss 2, p 168 (2021)
The purpose of this paper is to infer a dynamic graph as a global (collective) model of time-varying measurements at a set of network nodes. This model captures both pairwise as well as higher order interactions (i.e., more than two nodes) among the
Externí odkaz:
https://doaj.org/article/6cbc7394cc9c451c895cfacba4e5869e
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Nature Communications
Nature communications, vol 12, iss 1
Nature Communications
Nature communications, vol 12, iss 1
Imaging the activity of neurons that are widely distributed across brain regions deep in scattering tissue at high speed remains challenging. Here, we introduce an open-source system with Dual Independent Enhanced Scan Engines for Large field-of-view
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f24c55d006ec762728b86ce9922c66b2
https://doaj.org/article/61e2b203f08348f7bc349521ead6e6c7
https://doaj.org/article/61e2b203f08348f7bc349521ead6e6c7
Autor:
Nora S Wolcott, Michael J. Goard, William T. Redman, Kevin K Sit, Tyler D Marks, Che-Hang Yu, Luca Montelisciani, Gabriel Luna, Spencer L. Smith
Publikováno v:
eLife. 11
The hippocampus consists of a stereotyped neuronal circuit repeated along the septal-temporal axis. This transverse circuit contains distinct subfields with stereotyped connectivity that support crucial cognitive processes, including episodic and spa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1032731b48db8e73acd6dcf5622d88b
https://doi.org/10.7554/elife.75391
https://doi.org/10.7554/elife.75391
Autor:
Seong-Wook Park, Allison M. Ahrens, Ichun Anderson Chen, Mitchell Clough, Jerry L. Chen, Jeffrey N. Stirman, Spencer L. Smith
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
Nature Communications
Nature Communications
Understanding brain function requires monitoring local and global brain dynamics. Two-photon imaging of the brain across mesoscopic scales has presented trade-offs between imaging area and acquisition speed. We describe a flexible cellular resolution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::648b88a8d6bfe96065a437a9afb68d4b
https://doi.org/10.1038/s41467-021-26737-3
https://doi.org/10.1038/s41467-021-26737-3
Publikováno v:
ICASSP
The purpose of this paper is to infer a global (collective) model of time-varying responses of a set of nodes as a dynamic graph, where the individual time series are respectively observed at each of the nodes. The motivation of this work lies in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0462bffa5c0839e608615e3dacf9098e
https://doi.org/10.1109/icassp39728.2021.9413744
https://doi.org/10.1109/icassp39728.2021.9413744
Publikováno v:
Current Biology. 32:2810-2820.e5
Mice have a constellation of higher visual areas, but their functional specializations are unclear. Here, we used a data-driven approach to examine neuronal representations of complex visual stimuli across mouse higher visual areas, measured using la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1b1ee7936ee99988b3dc1d01622f3df
https://doi.org/10.1016/j.cub.2022.04.091
https://doi.org/10.1016/j.cub.2022.04.091
Publikováno v:
Conference on Lasers and Electro-Optics.
We developed a dual-wavelength excitation, large field-of-view (25 mm2) two-photon microscope with temporal multiplexing and two completely independent scan engines coupled into the same objective for imaging in multiple areas with multiple wavelengt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a25033e1b5dc43ebeaeb39171f2b09b
https://doi.org/10.1364/cleo_si.2021.sw2d.1
https://doi.org/10.1364/cleo_si.2021.sw2d.1