Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Spencer G. Gordon"'
Autor:
Spencer G Gordon, Ofer Rog
Publikováno v:
PLoS Genetics, Vol 19, Iss 7, p e1010822 (2023)
The successful delivery of genetic material to gametes requires tightly regulated interactions between the parental chromosomes. Central to this regulation is a conserved chromosomal interface called the synaptonemal complex (SC), which brings the pa
Externí odkaz:
https://doaj.org/article/062448e257c440baa6c60dd6d298901d
Publikováno v:
PLoS Genetics, Vol 17, Iss 3, p e1009205 (2021)
During sexual reproduction the parental homologous chromosomes find each other (pair) and align along their lengths by integrating local sequence homology with large-scale contiguity, thereby allowing for precise exchange of genetic information. The
Externí odkaz:
https://doaj.org/article/a4d48cfb3dce459a9f18613f216f16e1
Publikováno v:
Chromosoma
Alignment of the parental chromosomes during meiotic prophase is key to the formation of genetic exchanges, or crossovers, and consequently to the successful production of gametes. In almost all studied organisms, alignment involves synapsis: the ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7b0cd99fc94f438f31c6fd93f1aa69a
https://doi.org/10.1007/s00412-021-00763-y
https://doi.org/10.1007/s00412-021-00763-y
Autor:
David E Almanzar, Spencer G Gordon, Chloe Bristow, Antonia Hamrick, Lexy von Diezmann, Hanwenheng Liu, Ofer Rog
Publikováno v:
Life Science Alliance. 6:e202301906
During meiosis, programmed double-strand DNA breaks are repaired to form exchanges between the parental chromosomes called crossovers. Chromosomes lacking a crossover fail to segregate accurately into the gametes, leading to aneuploidy. In addition t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f9a84b9cd147dc06fb6037c5ab1bf12
https://doi.org/10.26508/lsa.202301906
https://doi.org/10.26508/lsa.202301906
Publikováno v:
Curr Biol
Sexual reproduction shuffles the parental genomes to generate new genetic combinations. To achieve that, the genome is subjected to numerous double-strand breaks, the repair of which involves two crucial decisions: repair pathway and repair template
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32f6c15efcfef88bc1df79c99bdb65fc
https://europepmc.org/articles/PMC8051885/
https://europepmc.org/articles/PMC8051885/
Synaptonemal Complex dimerization regulates chromosome alignment and crossover patterning in meiosis
Publikováno v:
PLoS Genetics, Vol 17, Iss 3, p e1009205 (2021)
PLoS Genetics
PLoS Genetics
During sexual reproduction the parental homologous chromosomes find each other (pair) and align along their lengths by integrating local sequence homology with large-scale contiguity, thereby allowing for precise exchange of genetic information. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::980848da6f55b8c44ecd6ee83f273bc9
https://doaj.org/article/a4d48cfb3dce459a9f18613f216f16e1
https://doaj.org/article/a4d48cfb3dce459a9f18613f216f16e1
Sexual reproduction shuffles the parental genomes to generate new genetic combinations. To achieve that, the genome is subjected to numerous double-strand breaks, the repair of which involves two crucial decisions: repair pathway and repair template.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8016f5f47359841ec4485e54f064dfcc
https://doi.org/10.1101/2020.07.22.216614
https://doi.org/10.1101/2020.07.22.216614