Differential sex-dependent susceptibility to diastolic dysfunction and arrhythmia in cardiomyocytes from obese diabetic HFpEF model.

Autor: Mira Hernandez J; Department of Pharmacology, University of California, Davis, CA, USA.; Research Group Biogenesis, Faculty of Agricultural Sciences, Veterinary Medicine, University of Antioquia, Medellin-Colombia., Shen EY; Department of Pharmacology, University of California, Davis, CA, USA., Ko CY; Department of Pharmacology, University of California, Davis, CA, USA., Hourani Z; Department of Cellular and Molecular Medicine, University of Arizona, Tucson, AZ, USA., Spencer ER; Department of Pharmacology, University of California, Davis, CA, USA., Smoliarchuk D; Department of Pharmacology, University of California, Davis, CA, USA., Bossuyt J; Department of Pharmacology, University of California, Davis, CA, USA., Granzier H; Department of Cellular and Molecular Medicine, University of Arizona, Tucson, AZ, USA., Bers DM; Department of Pharmacology, University of California, Davis, CA, USA., Hegyi B; Department of Pharmacology, University of California, Davis, CA, USA.

Publikováno v: Cardiovascular research [Cardiovasc Res] 2024 Apr 26. Date of Electronic Publication: 2024 Apr 26.

Spike height improves prediction of future seizure risk.

Autor: Chinappen DM; Massachusetts General Hospital, Department of Neurology, Boston, MA 02114, USA; Graduate Program for Neuroscience, Boston University, Boston, MA, USA; Department of Mathematics and Statistics, and Center for Systems Neuroscience, Boston University, Boston, MA, USA. Electronic address: dchinappen@mgh.harvard.edu., Xiao G; Massachusetts General Hospital, Department of Neurology, Boston, MA 02114, USA; Johns Hopkins University School of Medicine, Baltimore, MD, USA; Harvard University, Cambridge, MA, USA. Electronic address: gxiao3@mgh.harvard.edu., Jing J; Massachusetts General Hospital, Department of Neurology, Boston, MA 02114, USA; Harvard Medical School, Boston, MA, USA. Electronic address: jjing@partners.org., Spencer ER; Massachusetts General Hospital, Department of Neurology, Boston, MA 02114, USA; Graduate Program for Neuroscience, Boston University, Boston, MA, USA. Electronic address: erss@bu.edu., Eden UT; Department of Mathematics and Statistics, and Center for Systems Neuroscience, Boston University, Boston, MA, USA. Electronic address: tzvi@bu.edu., Kramer MA; Department of Mathematics and Statistics, and Center for Systems Neuroscience, Boston University, Boston, MA, USA. Electronic address: mak@bu.edu., Westover MB; Massachusetts General Hospital, Department of Neurology, Boston, MA 02114, USA; Harvard Medical School, Boston, MA, USA. Electronic address: mwestover@mgh.harvard.edu., Chu CJ; Massachusetts General Hospital, Department of Neurology, Boston, MA 02114, USA; Harvard Medical School, Boston, MA, USA. Electronic address: cjchu@mgh.harvard.edu.

Publikováno v: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology [Clin Neurophysiol] 2023 Jun; Vol. 150, pp. 49-55. Date of Electronic Publication: 2023 Mar 21.

Longitudinal EEG model detects antisense oligonucleotide treatment effect and increased UBE3A in Angelman syndrome.

Autor: Spencer ER; Department of Mathematics and Statistics, Boston University, 02215 Boston, MA, USA.; Department of Neurology, Massachusetts General Hospital, 02114 Boston, MA, USA., Shi W; Department of Neurology, Massachusetts General Hospital, 02114 Boston, MA, USA.; Harvard Medical School, 02115 Boston, MA, USA., Komorowski RW; Biogen Inc, 02142 Cambridge, MA, USA., Gilbert JP; Biogen Inc, 02142 Cambridge, MA, USA., Ostrowski LM; Department of Neurology, Massachusetts General Hospital, 02114 Boston, MA, USA.; School of Medicine, University of California, 92092 San Diego, CA, USA., Bird LM; Department of Pediatrics, University of California, 92093 San Diego, CA, USA., Thibert R; Department of Neurology, Massachusetts General Hospital, 02114 Boston, MA, USA.; Harvard Medical School, 02115 Boston, MA, USA., Bao C; Biogen Inc, 02142 Cambridge, MA, USA., Molloy F; Biogen Inc, 02142 Cambridge, MA, USA., Calhoun M; Biogen Inc, 02142 Cambridge, MA, USA., Koirala S; Biogen Inc, 02142 Cambridge, MA, USA., Jafar-Nejad P; Ionis Pharmaceuticals, 92010 Carlsbad, CA, USA., Rigo F; Ionis Pharmaceuticals, 92010 Carlsbad, CA, USA., Kramer MA; Department of Mathematics and Statistics, Boston University, 02215 Boston, MA, USA., Chu CJ; Department of Neurology, Massachusetts General Hospital, 02114 Boston, MA, USA.; Harvard Medical School, 02115 Boston, MA, USA.

Publikováno v: Brain communications [Brain Commun] 2022 Apr 26; Vol. 4 (3), pp. fcac106. Date of Electronic Publication: 2022 Apr 26 (Print Publication: 2022).

Delta power robustly predicts cognitive function in Angelman syndrome.

Autor: Ostrowski LM; Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA.; School of Medicine, University of California, San Diego, California, USA., Spencer ER; Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA.; Department of Mathematics and Statistics, Boston University, Boston, Massachusetts, USA., Bird LM; Department of Pediatrics, University of California, San Diego, California, USA., Thibert R; Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA.; Harvard Medical School, Boston, Massachusetts, USA., Komorowski RW; Division of Clinical Development, Biogen Inc, Cambridge, Massachusetts, USA., Kramer MA; Department of Mathematics and Statistics, Boston University, Boston, Massachusetts, USA., Chu CJ; Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA.; Harvard Medical School, Boston, Massachusetts, USA.

Publikováno v: Annals of clinical and translational neurology [Ann Clin Transl Neurol] 2021 Jul; Vol. 8 (7), pp. 1433-1445. Date of Electronic Publication: 2021 May 28.

Focal Sleep Spindle Deficits Reveal Focal Thalamocortical Dysfunction and Predict Cognitive Deficits in Sleep Activated Developmental Epilepsy.

Autor: Kramer MA; Department of Mathematics and Statistics, Boston University, Boston, Massachusetts 02215., Stoyell SM; Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts 02114., Chinappen D; Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts 02114., Ostrowski LM; Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts 02114., Spencer ER; Department of Mathematics and Statistics, Boston University, Boston, Massachusetts 02215., Morgan AK; Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts 02114., Emerton BC; Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts 02114., Jing J; Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts 02114.; Harvard Medical School, Boston, Massachusetts 02115., Westover MB; Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts 02114.; Harvard Medical School, Boston, Massachusetts 02115., Eden UT; Department of Mathematics and Statistics, Boston University, Boston, Massachusetts 02215., Stickgold R; Harvard Medical School, Boston, Massachusetts 02115.; Department of Psychiatry, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215., Manoach DS; Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts 02114.; Harvard Medical School, Boston, Massachusetts 02115.; Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, Massachusetts 02129., Chu CJ; Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts 02114 cjchu@mgh.harvard.edu.; Department of Psychiatry, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215.

Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2021 Feb 24; Vol. 41 (8), pp. 1816-1829. Date of Electronic Publication: 2021 Jan 19.