Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Spencer, Brightman"'
Autor:
Francesco Borriello, Carlo Pietrasanta, Jacqueline C. Y. Lai, Lois M. Walsh, Pankaj Sharma, David N. O’Driscoll, Juan Ramirez, Spencer Brightman, Lorenza Pugni, Fabio Mosca, David J. Burkhart, David J. Dowling, Ofer Levy
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Immunization is key to preventing infectious diseases, a leading cause of death early in life. However, due to age-specific immunity, vaccines often demonstrate reduced efficacy in newborns and young infants as compared to adults. Here, we combined i
Externí odkaz:
https://doaj.org/article/3a7316b0adc1486ea4a548622aca97e2
Autor:
Siming Sun, Jay Patel, Alexis Wascher, Evangeline S. Mose, Dawn Jaquish, Spencer Brightman, Stephen Schoenberger, Andrew M. Lowy, Tatiana Hurtado de Mendoza
Publikováno v:
Cancer Research. 82:C021-C021
Immunotherapy has become a standard of care treatment for many cancer types. Anti-tumor immune responses are elicited against neoantigens that arise from genetic alterations within tumor cells, and high tumor mutational burden increases the likelihoo
Autor:
David J. Dowling, Holly Sanders, Wing Ki Cheng, Sweta Joshi, Spencer Brightman, Ilana Bergelson, Carlo Pietrasanta, Simon Daniel Van Haren, Sandra van Amsterdam, Jeffrey Fernandez, Germie P.J.M. van den Dobbelsteen, Ofer Levy
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
Background. Group B Neisseria meningitidis, an endotoxin-producing gram-negative bacterium, causes the highest incidence of group B meningococcus (MenB) disease in the first year of life. The Bexsero vaccine is indicated in Europe from 8 weeks of age
Externí odkaz:
https://doaj.org/article/429d5895912a45e697300e6c6b16774e
Autor:
Eva Guinan, David E Avigan, Robert J Soiffer, Nancy J Bunin, Lisa L Brennan, Ilana Bergelson, Spencer Brightman, Al Ozonoff, Patrick J Scannon, Ofer Levy
Publikováno v:
F1000Research, Vol 4 (2015)
Bacterial infection and inflammation contribute significantly to the morbidity and mortality of myeloablative allogeneic hematopoietic cell transplantation (HCT). Endotoxin, a component of the outer membrane of Gram-negative bacteria, is a potent inf
Externí odkaz:
https://doaj.org/article/38a21c9830564e2d829e4fd9bc79c3cd
Autor:
Dheeraj Soni, Francesco Borriello, David A Scott, Al Ozonoff, Spencer Brightman, Jennifer Smith, Caroline Shamu, Juan C Ramirez, Lindsey Robert Baden, Wing Ki Cheng, Simon Daniel van Haren, Matthew Pettengill, David J Dowling, Ofer Levy
Publikováno v:
The Journal of Immunology. 204:166.19-166.19
Infection is a significant cause of mortality and immunization is the most promising biomedical intervention to reduce this burden. However, multiple booster doses are often required to protect those with distinct immunity such as the young, elders,
Autor:
David J. Dowling, Alyson J. Smith, Francesco Borriello, Spencer Brightman, Simone Schüller, Hélène Bazin, David J. Burkhart, Ofer Levy, Jay T. Evans
Publikováno v:
The Journal of Immunology. 200:180.24-180.24
Infection is the most common cause of mortality early in life, in large measure due to suboptimal early life vaccination strategies as compared to older age groups. New adjuvants are absolutely cardinal to further optimize current immunization approa
Autor:
David J, Dowling, Evan A, Scott, Annette, Scheid, Ilana, Bergelson, Sweta, Joshi, Carlo, Pietrasanta, Spencer, Brightman, Guzman, Sanchez-Schmitz, Simon D, Van Haren, Jana, Ninković, Dina, Kats, Cristiana, Guiducci, Alexandre, de Titta, Daniel K, Bonner, Sachiko, Hirosue, Melody A, Swartz, Jeffrey A, Hubbell, Ofer, Levy
Publikováno v:
The Journal of Allergy and Clinical Immunology
Background Newborns display distinct immune responses, leaving them vulnerable to infections and impairing immunization. Targeting newborn dendritic cells (DCs), which integrate vaccine signals into adaptive immune responses, might enable development
Autor:
Gary Grossman, Edwin D. Fuller
The Red Hotel series takes readers on a thrilling journey through a world teetering on the edge of chaos. From tracking down the mastermind behind a devastating bomb attack in Tokyo to unraveling a calculated act of war by a powerful global superpowe
Autor:
Gary Grossman, Edwin D. Fuller
The Arctic ice is melting, the waters are warming, and Russian President Nicolai Gorshkov is one step closer to monopolizing the oil industry and funding his expansionism plans past Ukraine and Latvia. Russian-backed attacks have shut down the Suez C