Zobrazeno 1 - 10
of 416
pro vyhledávání: '"Spellman Paul T"'
Autor:
Ak, Çiğdem, Sayar, Zeynep, Thibault, Guillaume, Burlingame, Erik A., Kuykendall, M.J., Eng, Jennifer, Chitsazan, Alex, Chin, Koei, Adey, Andrew C., Boniface, Christopher, Spellman, Paul T., Thomas, George V., Kopp, Ryan P., Demir, Emek, Chang, Young Hwan, Stavrinides, Vasilis, Eksi, Sebnem Ece
Publikováno v:
In iScience 20 September 2024 27(9)
Autor:
Hill Steven M, Neve Richard M, Bayani Nora, Kuo Wen-Lin, Ziyad Safiyyah, Spellman Paul T, Gray Joe W, Mukherjee Sach
Publikováno v:
BMC Bioinformatics, Vol 13, Iss 1, p 94 (2012)
Abstract Background An important question in the analysis of biochemical data is that of identifying subsets of molecular variables that may jointly influence a biological response. Statistical variable selection methods have been widely used for thi
Externí odkaz:
https://doaj.org/article/ea3b77fa7b73436e86d11a1d59c42eac
Autor:
Chang Hang, Fontenay Gerald V, Han Ju, Cong Ge, Baehner Frederick L, Gray Joe W, Spellman Paul T, Parvin Bahram
Publikováno v:
BMC Bioinformatics, Vol 12, Iss 1, p 484 (2011)
Abstract Background Our goals are to develop a computational histopathology pipeline for characterizing tumor types that are being generated by The Cancer Genome Atlas (TCGA) for genomic association. TCGA is a national collaborative program where dif
Externí odkaz:
https://doaj.org/article/39be0a2d24a44c019a127697db90f18f
A systems analysis of the chemosensitivity of breast cancer cells to the polyamine analogue PG-11047
Autor:
Feiler Heidi S, Bayani Nora, Wang Nicholas J, Hu Zhi, Fontenay Gerald V, Sadanandam Anguraj, Heiser Laura M, Gibb William J, Bhattacharya Sanchita, Ziyad Safiyyah, Das Debopriya, Kuo Wen-Lin, Neve Richard M, Wyrobek Andrew J, Spellman Paul T, Marton Laurence J, Gray Joe W
Publikováno v:
BMC Medicine, Vol 7, Iss 1, p 77 (2009)
Abstract Background Polyamines regulate important cellular functions and polyamine dysregulation frequently occurs in cancer. The objective of this study was to use a systems approach to study the relative effects of PG-11047, a polyamine analogue, a
Externí odkaz:
https://doaj.org/article/3d035572d9e24b00a18da4f7a529a83a
Autor:
Bondy Melissa, Walther Axel, Warren Robert, Richardson Andrea L, Wang Zhigang C, Moorhead Martin, Zhang Li, Sapolsky Ronald, Karlin-Neumann George, Carlton Victoria EH, Wang Yuker, Sahin Aysegul, Krahe Ralf, Tuna Musaffe, Thompson Patricia A, Spellman Paul T, Gray Joe W, Mills Gordon B, Faham Malek
Publikováno v:
BMC Medical Genomics, Vol 2, Iss 1, p 8 (2009)
Abstract Background A major challenge facing DNA copy number (CN) studies of tumors is that most banked samples with extensive clinical follow-up information are Formalin-Fixed Paraffin Embedded (FFPE). DNA from FFPE samples generally underperforms o
Externí odkaz:
https://doaj.org/article/e44c90789bbc4b0193eca2ed6c900864
Publikováno v:
BMC Bioinformatics, Vol 10, Iss 1, p 2 (2009)
Abstract Background Biological studies involve a growing number of distinct high-throughput experiments to characterize samples of interest. There is a lack of methods to visualize these different genomic datasets in a versatile manner. In addition,
Externí odkaz:
https://doaj.org/article/ca86994be7d94b9d9036673b8e12832b
Autor:
Miller Dianne M, Wang Yuker, Spellman Paul T, Smith Margaret, Blood Katherine A, Kalloger Steve E, Kaurah Pardeep, Ridge Yolanda, Troussard Armelle, Young Sean, Boyd Niki, De Luca Alessandro, Press Joshua Z, Horsman Doug, Faham Malek, Gilks C Blake, Gray Joe, Huntsman David G
Publikováno v:
BMC Cancer, Vol 8, Iss 1, p 17 (2008)
Background Subclassification of ovarian carcinomas can be used to guide treatment and determine prognosis. Germline and somatic mutations, loss of heterozygosity (LOH), and epigenetic events such as promoter hypermethylation can lead to decreased exp
Externí odkaz:
https://doaj.org/article/096442dbd4a0466895406b719c8f2e30
Autor:
White Joseph, Stoeckert Christian J, Sherlock Gavin, Quackenbush John, Petersen Kjell, Miller Michael, Maier Donald S, Liu Junmin, Irizarry Rafael A, Holloway Ele, Farne Anna, Causton Helen C, Spellman Paul T, Rocca-Serra Philippe, Rayner Tim F, Whetzel Patricia L, Wymore Farrell, Parkinson Helen, Sarkans Ugis, Ball Catherine A, Brazma Alvis
Publikováno v:
BMC Bioinformatics, Vol 7, Iss 1, p 489 (2006)
Abstract Background Sharing of microarray data within the research community has been greatly facilitated by the development of the disclosure and communication standards MIAME and MAGE-ML by the MGED Society. However, the complexity of the MAGE-ML f
Externí odkaz:
https://doaj.org/article/f5e312ee926247f780445c799b4eaaeb
Autor:
O’Brien, Timothy D., Potter, Amiee B., Driscoll, Catherine C., Goh, Gregory, Letaw, John H., McCabe, Sarah, Thanner, Jane, Kulkarni, Arpita, Wong, Rossana, Medica, Samuel, Week, Tiana, Buitrago, Jacob, Larson, Aaron, Camacho, Katie Johnson, Brown, Kim, Crist, Rachel, Conrad, Casey, Evans-Dutson, Sara, Lutz, Ryan, Mitchell, Asia, Anur, Pavana, Serrato, Vanessa, Shafer, Autumn, Marriott, Lisa K., Hamman, K.J., Mulford, Amelia, Wiszniewski, Wojciech, Sampson, Jone E., Adey, Andrew, O’Roak, Brian J., Harrington, Christina A., Shannon, Jackilen, Spellman, Paul T., Richards, C. Sue
Publikováno v:
In The American Journal of Human Genetics 3 August 2023 110(8):1249-1265
Autor:
Rubin Gerald M, Spellman Paul T
Publikováno v:
Journal of Biology, Vol 1, Iss 1, p 5 (2002)
Abstract Background Transcriptional regulation in eukaryotes generally operates at the level of individual genes. Regulation of sets of adjacent genes by mechanisms operating at the level of chromosomal domains has been demonstrated in a number of ca
Externí odkaz:
https://doaj.org/article/da195a7052644591a05d8896a6b3a704