Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Spela Binter"'
Autor:
Julia Ludwig, Stephen W. Scally, Giulia Costa, Sandro Hoffmann, Rajagopal Murugan, Jana Lossin, Katherine Prieto, Anna Obraztsova, Nina Lobeto, Blandine Franke-Fayard, Chris J. Janse, Celia Lebas, Nicolas Collin, Spela Binter, Paul Kellam, Elena A. Levashina, Hedda Wardemann, Jean-Philippe Julien
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-14 (2023)
Abstract The development of an effective and durable vaccine remains a central goal in the fight against malaria. Circumsporozoite protein (CSP) is the major surface protein of sporozoites and the target of the only licensed Plasmodium falciparum (Pf
Externí odkaz:
https://doaj.org/article/e21e8d2652bd4aaba4120441ac9e5abb
Autor:
Julia Ludwig, Stephen W. Scally, Giulia Costa, Sandro Hoffmann, Rajagopal Murugan, Jana Lossin, Katherine Prieto, Anna Obraztsova, Nina Lobeto, Blandine Franke-Fayard, Chris J. Janse, Celia Lebas, Nicolas Collin, Spela Binter, Paul Kellam, Elena A. Levashina, Hedda Wardemann, Jean-Philippe Julien
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/b04564d582c142d78add34d9a8e7e92b
Autor:
Elaine Thai, Rajagopal Murugan, Špela Binter, Clare Burn Aschner, Katherine Prieto, Audrey Kassardjian, Anna S. Obraztsova, Ryu Won Kang, Yevel Flores-Garcia, Shamika Mathis-Torres, Kan Li, Gillian Q. Horn, Richard H.C. Huntwork, Judith M. Bolscher, Marloes H.C. de Bruijni, Robert Sauerwein, S. Moses Dennison, Georgia D. Tomaras, Fidel Zavala, Paul Kellam, Hedda Wardemann, Jean-Philippe Julien
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113330- (2023)
Summary: IGHV3-33-encoded antibodies are prevalent in the human humoral response against the Plasmodium falciparum circumsporozoite protein (PfCSP). Among VH3-33 antibodies, cross-reactivity between PfCSP major repeat (NANP), minor (NVDP), and juncti
Externí odkaz:
https://doaj.org/article/08227defc9c24c6faea6294d29f2de60
Autor:
Gytis Dudas, Luiz Max Carvalho, Andrew Rambaut, Trevor Bedford, Ali M. Somily, Mazin Barry, Sarah S. Al Subaie, Abdulaziz A. BinSaeed, Fahad A. Alzamil, Waleed Zaher, Theeb Al Qahtani, Khaldoon Al Jerian, Scott J.N. McNabb, Imad A. Al-Jahdali, Ahmed M. Alotaibi, Nahid A. Batarfi, Matthew Cotten, Simon J. Watson, Spela Binter, Paul Kellam
Middle East respiratory syndrome coronavirus (MERS-CoV) is a zoonotic virus originating in camels that has been causing significant mortality and morbidity in humans in the Arabian Peninsula. The epidemiology of the virus remains poorly understood, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc9c6189d968989b4e26b00aebf7cb16
https://doi.org/10.1101/173211
https://doi.org/10.1101/173211
Autor:
Eve Richardson, Špela Binter, Miha Kosmac, Marie Ghraichy, Valentin von Niederhäusern, Aleksandr Kovaltsuk, Jacob D Galson, Johannes Trück, Dominic F Kelly, Charlotte M Deane, Paul Kellam, Simon J Watson
Publikováno v:
eLife, Vol 12 (2023)
Immunoglobulin loci-transgenic animals are widely used in antibody discovery and increasingly in vaccine response modelling. In this study, we phenotypically characterised B-cell populations from the Intelliselect Transgenic mouse (Kymouse) demonstra
Externí odkaz:
https://doaj.org/article/8edf1acdf29a48b99e78fa6ee6f633dc
Autor:
Iga Kucharska, Špela Binter, Rajagopal Murugan, Stephen W Scally, Julia Ludwig, Katherine Prieto, Elaine Thai, Giulia Costa, Kan Li, Gillian Q Horn, Yevel Flores-Garcia, Alexandre Bosch, Taylor Sicard, John L Rubinstein, Fidel Zavala, S Moses Dennison, Georgia D Tomaras, Elena A Levashina, Paul Kellam, Hedda Wardemann, Jean-Philippe Julien
Publikováno v:
PLoS Pathogens, Vol 18, Iss 11, p e1010999 (2022)
Antibodies targeting the human malaria parasite Plasmodium falciparum circumsporozoite protein (PfCSP) can prevent infection and disease. PfCSP contains multiple central repeating NANP motifs; some of the most potent anti-infective antibodies against
Externí odkaz:
https://doaj.org/article/8c8d7d9367ac4e39a094144bab03ffbb
Autor:
David Oyen, Jonathan L Torres, Phillip C Aoto, Yevel Flores-Garcia, Špela Binter, Tossapol Pholcharee, Sean Carroll, Sini Reponen, Rachael Wash, Qi Liang, Franck Lemiale, Emily Locke, Allan Bradley, C Richter King, Daniel Emerling, Paul Kellam, Fidel Zavala, Andrew B Ward, Ian A Wilson
Publikováno v:
PLoS Pathogens, Vol 16, Iss 3, p e1008373 (2020)
Lasting protection has long been a goal for malaria vaccines. The major surface antigen on Plasmodium falciparum sporozoites, the circumsporozoite protein (PfCSP), has been an attractive target for vaccine development and most protective antibodies s
Externí odkaz:
https://doaj.org/article/2b45fbb0cb2843a2913970e92e8e5bed