Growth stimulation of UV-induced DNA damage retaining epidermal basal cells gives rise to clusters of p53 overexpressing cells

Autor: Nijhof, Joanne G.W., Mulder, Aat M., Speksnijder, Ewoud N., Hoogervorst, Esther M., Mullenders, Leon H.F., de Gruijl, Frank R.

Publikováno v: In DNA Repair 1 November 2007 6(11):1642-1650

The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice

Autor: Krais, Annette M., Speksnijder, Ewoud N., Melis, Joost P. M., Indra, Radek, Moserova, Michaela, Godschalk, Roger W., van Schooten, Frederik-J., Seidel, Albrecht, Kopka, Klaus, Schmeiser, Heinz H., Stiborova, Marie, Phillips, David H., Luijten, Mirjam, Arlt, Volker M.

Publikováno v: Krais, A M, Speksnijder, E N, Melis, J P M, Indra, R, Moserova, M, Godschalk, R W, van Schooten, F-J, Seidel, A, Kopka, K, Schmeiser, H H, Stiborova, M, Phillips, D H, Luijten, M & Arlt, V M 2016, ' The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice ', Archives of Toxicology, vol. 90, no. 4, pp. 839-851 . https://doi.org/10.1007/s00204-015-1531-8

The tumour suppressor p53 is one of the most important cancer genes. Previous findings have shown that p53 expression can influence DNA adduct formation of the environmental carcinogen benzo[a]pyrene (BaP) in human cells, indicating a role for p53 in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e7fd1fb65206cbf4fa3e2733261c6ffa
https://kclpure.kcl.ac.uk/en/publications/30909f28-aefb-442a-b2b4-f097edeb9d82

Development of metastatic HER2(+) breast cancer is independent of the adaptive immune system

Autor: Ciampricotti, Metamia, Vrijland, Kim, Hau, Cheei-Sing, Pemovska, Tea, Doornebal, Chris W, Speksnijder, Ewoud N, Wartha, Katharina, Jonkers, Jos, de Visser, Karin E

Publikováno v: The Journal of Pathology; Vol 224
The Journal of Pathology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::03397018d070fae62aaf9ee4dea4e90c

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