Low levels of intra-tumoural T cells in breast cancer identify clinically frail patients with shorter disease-specific survival

Autor: Speigl, Lisa, Grieb, Alexandra, Janssen, Nicole, Hatse, Sigrid, Brouwers, Barbara, Smeets, Ann, Floris, Giuseppe, Bailur, Jithendra Kini, Kenis, Cindy, Neven, Patrick, Wildiers, Hans, Pawelec, Graham, Shipp, Christopher

Publikováno v: In Journal of Geriatric Oncology November 2018 9(6):606-612

Exploring the Potential for More Effective Cancer Treatment: Investigations on Tumour Immunity and Cancer Stem Cells in Breast Cancer and Melanoma

Autor: Speigl, Lisa

This thesis aimed to better understand the current hurdles preventing more effective cancer treatment. This was investigated from two angles, cancer stem cells (CSCs) and tumour immunity. CSCs possess the capacity of self-renewal and the ability to g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______707::01e61b5791f642bebf3d7369e3c1d851
https://hdl.handle.net/10900/138212

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CD14+ HLA-DR−/low MDSCs are elevated in the periphery of early-stage breast cancer patients and suppress autologous T cell proliferation.

Autor: Speigl, Lisa, Burow, Helen, Bailur, Jithendra Kini, Janssen, Nicole, Walter, Christina-Barbara, Pawelec, Graham, Shipp, Christopher

Publikováno v: Breast Cancer Research & Treatment; Apr2018, Vol. 168 Issue 2, p401-411, 11p

Putative Cancer Stem Cell Markers are Frequently Expressed by Melanoma Cells in Vitro and in Situ but are also Present in Benign Differentiated Cells.

Autor: Speigl L; Department of Internal Medicine II, University Hospital Tübingen, 72072 Tübingen, Germany., Janssen N; Department of Internal Medicine II, University Hospital Tübingen, 72072 Tübingen, Germany.; Current Affiliation: Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, 70376 Stuttgart, Germany., Weide B; Department of Dermatology, University Hospital Tübingen, 72076 Tübingen, Germany., Sinnberg T; Department of Dermatology, University Hospital Tübingen, 72076 Tübingen, Germany., Pawelec G; Department of Immunology, University of Tübingen, 72074 Tübingen, Germany.; Health Sciences North Research Institute, Sudbury, ON P3E 2H3, Canada., Shipp C; Department of Internal Medicine II, University Hospital Tübingen, 72072 Tübingen, Germany.

Publikováno v: Frontiers in bioscience (Landmark edition) [Front Biosci (Landmark Ed)] 2023 Sep 06; Vol. 28 (9), pp. 193.