Low extracellular vesicle concentrations predict survival in patients with heart failure.

Autor: Schöler D; Clinic for Gastroenterology, Hepatology and Infectious Diseases, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Loosen SH; Clinic for Gastroenterology, Hepatology and Infectious Diseases, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Wirtz TH; Department of Gastroenterology, Digestive Diseases and Intensive Care Medicine, RWTH Aachen University Hospital, Aachen, Germany., Brozat JF; Department of Gastroenterology, Digestive Diseases and Intensive Care Medicine, RWTH Aachen University Hospital, Aachen, Germany.; Department of Hepatology and Gastroenterology, Charite-Universitätsmedizin Berlin Campus Virchow-Klinikum (CVK) and Campus Charite Mitte (CCM), Berlin, Germany., Dos Santos Ferreira Grani LA; Clinic for Gastroenterology, Hepatology and Infectious Diseases, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Luedde T; Clinic for Gastroenterology, Hepatology and Infectious Diseases, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Heinrichs L; Clinic for Gastroenterology, Hepatology and Infectious Diseases, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Frank D; Internal Medicine III, University Hospital of Schleswig Holstein, Campus Kiel, Kiel, Germany., Koch A; Department of Gastroenterology, Digestive Diseases and Intensive Care Medicine, RWTH Aachen University Hospital, Aachen, Germany., Roderburg C; Clinic for Gastroenterology, Hepatology and Infectious Diseases, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Spehlmann ME; Internal Medicine III, University Hospital of Schleswig Holstein, Campus Kiel, Kiel, Germany.

Publikováno v: Frontiers in cardiovascular medicine [Front Cardiovasc Med] 2023 May 24; Vol. 10, pp. 1163525. Date of Electronic Publication: 2023 May 24 (Print Publication: 2023).

Heart Failure Severity Closely Correlates with Intestinal Dysbiosis and Subsequent Metabolomic Alterations.

Autor: Spehlmann ME; Department of Internal Medicine III, Cardiology, Angiology and Intensive Care Medicine, University Hospital of Schleswig-Holstein, Rosalind-Franklin Str. 12, 24105 Kiel, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Hamburg/Kiel/Lübeck, 24105 Kiel, Germany., Rangrez AY; Department of Internal Medicine III, Cardiology, Angiology and Intensive Care Medicine, University Hospital of Schleswig-Holstein, Rosalind-Franklin Str. 12, 24105 Kiel, Germany.; Department of Internal Medicine III, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Heidelberg/Mannheim, 69120 Heidelberg, Germany., Dhotre DP; National Centre for Cell Science, Pune 411021, India., Schmiedel N; Department of Internal Medicine III, Cardiology, Angiology and Intensive Care Medicine, University Hospital of Schleswig-Holstein, Rosalind-Franklin Str. 12, 24105 Kiel, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Hamburg/Kiel/Lübeck, 24105 Kiel, Germany., Chavan N; National Centre for Cell Science, Pune 411021, India., Bang C; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel, Rosalind-Franklin-Strasse 12, 24105 Kiel, Germany., Müller OJ; Department of Internal Medicine III, Cardiology, Angiology and Intensive Care Medicine, University Hospital of Schleswig-Holstein, Rosalind-Franklin Str. 12, 24105 Kiel, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Hamburg/Kiel/Lübeck, 24105 Kiel, Germany., Shouche YS; National Centre for Cell Science, Pune 411021, India., Franke A; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel, Rosalind-Franklin-Strasse 12, 24105 Kiel, Germany., Frank D; Department of Internal Medicine III, Cardiology, Angiology and Intensive Care Medicine, University Hospital of Schleswig-Holstein, Rosalind-Franklin Str. 12, 24105 Kiel, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Hamburg/Kiel/Lübeck, 24105 Kiel, Germany., Frey N; Department of Internal Medicine III, Cardiology, Angiology and Intensive Care Medicine, University Hospital of Schleswig-Holstein, Rosalind-Franklin Str. 12, 24105 Kiel, Germany.; Department of Internal Medicine III, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Heidelberg/Mannheim, 69120 Heidelberg, Germany.

Publikováno v: Biomedicines [Biomedicines] 2022 Mar 30; Vol. 10 (4). Date of Electronic Publication: 2022 Mar 30.

Identification of Disease-associated Traits and Clonotypes in the T Cell Receptor Repertoire of Monozygotic Twins Affected by Inflammatory Bowel Diseases.

Autor: Rosati E; Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany., Pogorelyy MV; Laboratory of comparative and functional genomic, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russian Federation.; Department of Translational Medicine, Pirogov Russian National Research Medical University [RNRMU], Moscow, Russian Federation., Dowds CM; Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany., Moller FT; Department of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark.; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Sorensen SB; Focused Research Unit for Molecular Diagnostic and Clinical Research, University Hospital of Southern Denmark, Aabenraa, Denmark.; Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark., Lebedev YB; Laboratory of comparative and functional genomic, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russian Federation., Frey N; Department of Internal Medicine III, University Hospital Schleswig-Holstein, Kiel, Germany., Schreiber S; Department of Internal Medicine I, University Hospital Schleswig-Holstein, Kiel, Germany., Spehlmann ME; Department of Internal Medicine III, University Hospital Schleswig-Holstein, Kiel, Germany., Andersen V; Focused Research Unit for Molecular Diagnostic and Clinical Research, University Hospital of Southern Denmark, Aabenraa, Denmark.; Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.; IRS-Center Sønderjylland, University of Southern Denmark, Odense, Denmark., Mamedov IZ; Laboratory of comparative and functional genomic, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russian Federation.; Department of Translational Medicine, Pirogov Russian National Research Medical University [RNRMU], Moscow, Russian Federation.; Laboratory of molecular biology, Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russian Federation.; CEITEC, Masaryk University, Brno, Czech Republic., Franke A; Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany.

Publikováno v: Journal of Crohn's & colitis [J Crohns Colitis] 2020 Jul 09; Vol. 14 (6), pp. 778-790.

miR-155 Predicts Long-Term Mortality in Critically Ill Patients Younger than 65 Years.

Autor: Tacke F; Department of Medicine III, University Hospital RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany., Spehlmann ME; Department of Internal Medicine III, University of Kiel, Schittenhelmstrasse 12, 24105 Kiel, Germany., Vucur M; Department of Medicine III, University Hospital RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany., Benz F; Department of Medicine III, University Hospital RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany., Luedde M; Department of Internal Medicine III, University of Kiel, Schittenhelmstrasse 12, 24105 Kiel, Germany., Cardenas DV; Department of Medicine III, University Hospital RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany., Roy S; Department of Medicine III, University Hospital RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany., Loosen S; Department of Medicine III, University Hospital RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany., Hippe HJ; Department of Internal Medicine III, University of Kiel, Schittenhelmstrasse 12, 24105 Kiel, Germany., Frey N; Department of Internal Medicine III, University of Kiel, Schittenhelmstrasse 12, 24105 Kiel, Germany., Trautwein C; Department of Medicine III, University Hospital RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany., Koch A; Department of Medicine III, University Hospital RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany., Roderburg C; Department of Medicine III, University Hospital RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany., Luedde T; Department of Medicine III, University Hospital RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany.

Publikováno v: Mediators of inflammation [Mediators Inflamm] 2019 Feb 24; Vol. 2019, pp. 6714080. Date of Electronic Publication: 2019 Feb 24 (Print Publication: 2019).

Serum levels of kisspeptin are elevated in critically ill patients.

Autor: Luedde M; Department of Internal Medicine III, University Clinic of Schleswig-Holstein, Kiel, Germany., Spehlmann ME; Department of Internal Medicine III, University Clinic of Schleswig-Holstein, Kiel, Germany., Hippe HJ; Department of Internal Medicine III, University Clinic of Schleswig-Holstein, Kiel, Germany., Loosen SH; Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany., Roy S; Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany., Vargas Cardenas D; Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany., Vucur M; Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany., Frey N; Department of Internal Medicine III, University Clinic of Schleswig-Holstein, Kiel, Germany., Koch A; Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany., Luedde T; Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany., Trautwein C; Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany., Tacke F; Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany., Roderburg C; Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany.

Publikováno v: PloS one [PLoS One] 2018 Oct 17; Vol. 13 (10), pp. e0206064. Date of Electronic Publication: 2018 Oct 17 (Print Publication: 2018).