Zobrazeno 1 - 10
of 1 754
pro vyhledávání: '"Specific binding"'
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-15 (2024)
Abstract Background Transcription factors (TFs) bind to DNA in a highly sequence-specific manner. This specificity manifests itself in vivo as differences in TF occupancy between the two alleles at heterozygous loci. Genome-scale assays such as ChIP-
Externí odkaz:
https://doaj.org/article/203b6acd35344567af1a6e1d3e57ec39
Publikováno v:
Shipin Kexue, Vol 44, Iss 23, Pp 252-269 (2023)
Phages are one of the most diverse and widely distributed organisms on the earth today, and have great advantages in eliminating bacteria, especially multi-drug resistant bacteria that are widespread at present. At present, a variety of bacteriophage
Externí odkaz:
https://doaj.org/article/1a1f1bec09714060b4cc8ffd1d410262
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-16 (2023)
Abstract Background Allele-specific binding (ASB) events occur when transcription factors (TFs) bind more favorably to one of the two parental alleles at heterozygous single nucleotide polymorphisms (SNPs). Evidence suggests that ASB events could rev
Externí odkaz:
https://doaj.org/article/ad8dd21843914d2f89c7a7f3accb6c31
Autor:
Øystein Kalsnes Jørstad, Stian Foss, Torleif Tollefsrud Gjølberg, Simone Mester, Mari Nyquist-Andersen, Magne Sand Sivertsen, Dag Fossum, Espen Gleditsch, Morten Carstens Moe, Jan Terje Andersen
Publikováno v:
International Journal of Retina and Vitreous, Vol 9, Iss 1, Pp 1-9 (2023)
Abstract Background Intravitreal injection (IVI) of antibody biologics is a key treatment approach in ophthalmology. Pharmaceutical compounding and storage of prefilled syringes for IVI must take place without impairing the structure and function of
Externí odkaz:
https://doaj.org/article/c8a9dc169ebd4e76999c85ad2677ecf6
Autor:
Puja Parekh, Patrick Begley, Maryam Jessop, Mark Aplin, Elena Missir, Helena McMeekin, Gosia Raczek, Nitasha Singh, Sabina Dizdarevic
Publikováno v:
European Journal of Hybrid Imaging, Vol 7, Iss 1, Pp 1-19 (2023)
Abstract Aim [123I]Ioflupane (DaTSCAN) has a high binding affinity to the dopamine (DA) transporter (DaT) and tenfold less affinity to serotonin (5-HT) transporter (SERT). Both neurotransmitters are considered to contribute to body weight regulation.
Externí odkaz:
https://doaj.org/article/5ed6906cb95d42359aa76521dce8e924
Publikováno v:
Materials Research Express, Vol 11, Iss 12, p 125102 (2024)
Bio/chemical sensors require high selectivity for specific targets. Carbon nanomaterials, especially graphene-based materials, are preferred in sensors due to their high surface area, superior electrical conductivity, mechanical strength, and flexibi
Externí odkaz:
https://doaj.org/article/45260f88e7794cea9b70c4c304bfddde
Publikováno v:
Epigenomes, Vol 8, Iss 2, p 23 (2024)
The post-genomic era has ushered in the extensive application of epigenetic editing tools, allowing for precise alterations of gene expression. The use of reprogrammable editors that carry transcriptional corepressors has significant potential for lo
Externí odkaz:
https://doaj.org/article/a29ee7d7367243eca2f99bddf6b339a2
Autor:
Ivayla Apostolova, Tassilo Schiebler, Catharina Lange, Franziska Lara Mathies, Wencke Lehnert, Susanne Klutmann, Ralph Buchert
Publikováno v:
EJNMMI Physics, Vol 10, Iss 1, Pp 1-18 (2023)
Abstract Background The specific binding ratio (SBR) of 123I-FP-CIT in the putamen is widely used to support the interpretation of dopamine transporter (DAT) SPECT. Automatic methods for computation of the putamen SBR often include stereotactical nor
Externí odkaz:
https://doaj.org/article/d31cadcac51b4c77a116d22e13df069b
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