Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Special Topic: Bioengineering of Cancer"'
Autor:
Dennis E. Discher, Adam J. Engler
Publikováno v:
APL Bioengineering
APL bioengineering, vol 2, iss 3
APL Bioengineering, Vol 2, Iss 3, Pp 031601-031601-4 (2018)
APL bioengineering, vol 2, iss 3
APL Bioengineering, Vol 2, Iss 3, Pp 031601-031601-4 (2018)
The physical and engineering sciences have much to offer in understanding, diagnosing, and even treating cancer. Microfluidics, imaging, materials, and diverse measurement devices are all helping to shift paradigms of tumorigenesis and dissemination.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fceed313b503ad3571af7e0c9fc5979
http://europepmc.org/articles/PMC6481711
http://europepmc.org/articles/PMC6481711
Publikováno v:
APL bioengineering, vol 2, iss 3
APL Bioengineering, Vol 2, Iss 3, Pp 031903-031903-18 (2018)
APL Bioengineering, Vol 2, Iss 3, Pp 031903-031903-18 (2018)
Glioblastoma (GBM) is the most common and invasive primary brain cancer. GBM tumors are characterized by diffuse infiltration, with tumor cells invading slowly through the hyaluronic acid (HA)-rich parenchyma toward vascular beds and then migrating r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28d29a25b1e2b2b8a823864c866aada0
https://escholarship.org/uc/item/32x982xn
https://escholarship.org/uc/item/32x982xn
Autor:
Swastika S. Bithi, Siva A. Vanapalli, Lauren S. Gollahon, Noshin Mubtasim, Caroline Schuster, Shamim M. Ahmmed, Adity A. Pore
Publikováno v:
APL Bioengineering
APL Bioengineering, Vol 2, Iss 3, Pp 032002-032002-14 (2018)
APL Bioengineering, Vol 2, Iss 3, Pp 032002-032002-14 (2018)
There is growing recognition that cell deformability can play an important role in cancer metastasis and diagnostics. Advancement of methods to characterize cell deformability in a high throughput manner and the capacity to process numerous samples c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9280c1be9fda117da400f64ec9a27e6c
http://europepmc.org/articles/PMC6481721
http://europepmc.org/articles/PMC6481721
Autor:
Kathryn M. Kingsmore, Scott T. Acton, Andrea Vaccari, Daniel Abler, Sophia X. Cui, Jennifer M. Munson, Frederick H. Epstein, Russell C. Rockne
Publikováno v:
APL Bioengineering
APL Bioengineering, Vol 2, Iss 3, Pp 031905-031905-15 (2018)
APL Bioengineering, Vol 2, Iss 3, Pp 031905-031905-15 (2018)
Glioblastoma (GBM), a highly aggressive form of brain tumor, is a disease marked by extensive invasion into the surrounding brain. Interstitial fluid flow (IFF), or the movement of fluid within the spaces between cells, has been linked to increased i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3391068c1788a014dfef24684378b41f
http://europepmc.org/articles/PMC6238644
http://europepmc.org/articles/PMC6238644
Autor:
Kandice Tanner
Publikováno v:
APL Bioengineering
APL Bioengineering, Vol 2, Iss 3, Pp 031801-031801-14 (2018)
APL Bioengineering, Vol 2, Iss 3, Pp 031801-031801-14 (2018)
Tumor latency and dormancy are obstacles to effective cancer treatment. In brain metastases, emergence of a lesion can occur at varying intervals from diagnosis and in some cases following successful treatment of the primary tumor. Genetic factors th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a681c8ae162ce6b9675b6cb64fe1e93
http://europepmc.org/articles/PMC6324204
http://europepmc.org/articles/PMC6324204
Autor:
Matthew R. Zanotelli, Cynthia A. Reinhart-King, Brandon Borde, Lawrence J. Bonassar, Danielle J. LaValley, Joseph Miller, Francois Bordeleau, Susan C. Pannullo, Dylan J. Parker
Publikováno v:
APL Bioengineering
APL Bioengineering, Vol 2, Iss 3, Pp 031901-031901-11 (2018)
APL Bioengineering, Vol 2, Iss 3, Pp 031901-031901-11 (2018)
Cells receive mechanical cues from their extracellular matrix (ECM), which direct migration, differentiation, apoptosis, and in some cases, the transition to a cancerous phenotype. As a result, there has been significant research to develop methods t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::711515b72cd8dba2e177eb0d3c9da78e
http://europepmc.org/articles/PMC6324208
http://europepmc.org/articles/PMC6324208
Publikováno v:
APL Bioengineering
APL Bioengineering, Vol 2, Iss 3, Pp 031906-031906-20 (2018)
APL Bioengineering, Vol 2, Iss 3, Pp 031906-031906-20 (2018)
Collective motions of groups of cells are observed in many biological settings such as embryo development, tissue formation, and cancer metastasis. To effectively model collective cell movement, it is important to incorporate cell specific features s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::315c19a7e8ddc9db1f029d5db8082fd8
https://pubmed.ncbi.nlm.nih.gov/31069315
https://pubmed.ncbi.nlm.nih.gov/31069315
Publikováno v:
APL Bioengineering, Vol 2, Iss 3, Pp 031904-031904-13 (2018)
APL Bioengineering
APL Bioengineering
Cancer cell migration is essential for metastasis, during which cancer cells move through the tumor and reach the blood vessels. In vivo, cancer cells are exposed to contact guidance and chemotactic cues. Depending on the strength of such cues, cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8f89d2784d4671b0482f88f861d8b44
https://doaj.org/article/d21333e0e4c24246a82467b9cea62db2
https://doaj.org/article/d21333e0e4c24246a82467b9cea62db2
Publikováno v:
APL Bioengineering, Vol 2, Iss 3, Pp 031701-031701-17 (2018)
APL Bioengineering
APL Bioengineering
Ovarian cancer remains a deadly diagnosis with an 85% recurrence rate and a 5-year survival rate of only 46%. The poor outlook of this disease has improved little over the past 50 years owing to the lack of early detection, chemoresistance and the co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b665056760eb01bfb86752336ff6e86
https://doi.org/10.1063/1.5024386
https://doi.org/10.1063/1.5024386
Autor:
Tanner J. McArdle, Claire Dietzsch, Brenda M. Ogle, Brian T. Freeman, Felicite K. Noubissi, Casey A Chitwood, Gabriel Jacobs, Annanya Banga
Publikováno v:
APL Bioengineering, Vol 2, Iss 3, Pp 031907-031907-19 (2018)
APL Bioengineering
APL Bioengineering
Cancer cell fusion was suggested as a mechanism of metastasis about a century ago. Since then, many additional modes of material transfer (i.e., tunneling nanotubes, and exosomes) to generate cell hybrids have been identified. However, studies docume
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afd9855d5971453a84d5110d4e95d4ae
https://doi.org/10.1063/1.5024744
https://doi.org/10.1063/1.5024744