Microbial rhodoquinone biosynthesis proceeds via an atypical RquA-catalyzed amino transfer from S-adenosyl-L-methionine to ubiquinone.

Autor: Neupane T; Department of Biochemistry & Molecular Biology, Dalhousie University, Halifax, NS, Canada., Chambers LR; Department of Chemistry and Biochemistry, Gonzaga University, Spokane, WA, USA., Godfrey AJ; Department of Chemistry and Biochemistry, Gonzaga University, Spokane, WA, USA., Monlux MM; Department of Chemistry and Biochemistry, Gonzaga University, Spokane, WA, USA., Jacobs EJ; Department of Chemistry and Biochemistry, Gonzaga University, Spokane, WA, USA., Whitworth S; Department of Chemistry and Biochemistry, Gonzaga University, Spokane, WA, USA., Spawn JE; Department of Chemistry and Biochemistry, Gonzaga University, Spokane, WA, USA., Clingman SHK; Department of Chemistry and Biochemistry, Gonzaga University, Spokane, WA, USA., Vergunst KL; Department of Biochemistry & Molecular Biology, Dalhousie University, Halifax, NS, Canada., Niven FM; Department of Chemistry and Biochemistry, Gonzaga University, Spokane, WA, USA., Townley JJ; Department of Chemistry and Biochemistry, Gonzaga University, Spokane, WA, USA., Orion IW; Department of Chemistry and Biochemistry, Gonzaga University, Spokane, WA, USA., Goodspeed CR; Department of Chemistry and Biochemistry, Gonzaga University, Spokane, WA, USA., Cooper KA; Department of Chemistry and Biochemistry, Gonzaga University, Spokane, WA, USA., Cronk JD; Department of Chemistry and Biochemistry, Gonzaga University, Spokane, WA, USA., Shepherd JN; Department of Chemistry and Biochemistry, Gonzaga University, Spokane, WA, USA. shepherd@gonzaga.edu., Langelaan DN; Department of Biochemistry & Molecular Biology, Dalhousie University, Halifax, NS, Canada. david.langelaan@dal.ca.

Publikováno v: Communications chemistry [Commun Chem] 2022 Aug 01; Vol. 5 (1), pp. 89. Date of Electronic Publication: 2022 Aug 01.