Zobrazeno 1 - 10
of 4 937
pro vyhledávání: '"Spatially resolved"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 1094-1105 (2024)
Most of the complex biological regulatory activities occur in three dimensions (3D). To better analyze biological processes, it is essential not only to decipher the molecular information of numerous cells but also to understand how their spatial con
Externí odkaz:
https://doaj.org/article/892533b8862547838303363e5fe65e7a
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 883-891 (2024)
With the emergence of advanced spatial transcriptomic technologies, there has been a surge in research papers dedicated to analyzing spatial transcriptomics data, resulting in significant contributions to our understanding of biology. The initial sta
Externí odkaz:
https://doaj.org/article/cc3229cf1993495ea358ebb47a126352
Autor:
Hongrui Duo, Yinghong Li, Yang Lan, Jingxin Tao, Qingxia Yang, Yingxue Xiao, Jing Sun, Lei Li, Xiner Nie, Xiaoxi Zhang, Guizhao Liang, Mingwei Liu, Youjin Hao, Bo Li
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-29 (2024)
Abstract Background Single-cell RNA sequencing (scRNA-seq) and spatially resolved transcriptomics (SRT) have led to groundbreaking advancements in life sciences. To develop bioinformatics tools for scRNA-seq and SRT data and perform unbiased benchmar
Externí odkaz:
https://doaj.org/article/279b7d0c771b4ebb83b4a5bb4b170b10
Autor:
Xi Jiang, Shidan Wang, Lei Guo, Bencong Zhu, Zhuoyu Wen, Liwei Jia, Lin Xu, Guanghua Xiao, Qiwei Li
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-25 (2024)
Abstract Current clustering analysis of spatial transcriptomics data primarily relies on molecular information and fails to fully exploit the morphological features present in histology images, leading to compromised accuracy and interpretability. To
Externí odkaz:
https://doaj.org/article/71facb4410dd4f5897e9d7bba33c06a8
Autor:
Haiyan Jiang, Bowen Zheng, Guang Hu, Lian Kuang, Tianyu Zhou, Sizheng Li, Xinyi Chen, Chuangjun Li, Dongming Zhang, Jinlan Zhang, Zengyan Yang, Jiuming He, Hongtao Jin
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 14, Iss 9, Pp 100971- (2024)
Pulmonary fibrosis (PF) is a chronic progressive end-stage lung disease. However, the mechanisms underlying the progression of this disease remain elusive. Presently, clinically employed drugs are scarce for the treatment of PF. Hence, there is an ur
Externí odkaz:
https://doaj.org/article/fa6b8e26a71d487cab3372c9bcbafe37
Publikováno v:
Next Materials, Vol 4, Iss , Pp 100202- (2024)
Applying nitriding in laser powder bed fusion additive manufacturing at custom build positions requires knowledge of the spatially and temporally resolved nitriding behaviour. Here we take steps toward this goal by sequential analysis of spatially re
Externí odkaz:
https://doaj.org/article/76e2edada94044928045d316326bfe4b
Autor:
Yudai Miyai, Shigeyuki Ishida, Kenichi Ozawa, Yoshiyuki Yoshida, Hiroshi Eisaki, Kenya Shimada, Hideaki Iwasawa
Publikováno v:
Science and Technology of Advanced Materials, Vol 25, Iss 1 (2024)
Electronic inhomogeneity arises ubiquitously as a consequence of adjacent and/or competing multiple phases or orders in strongly correlated electron systems. Gap inhomogeneity in high-[Formula: see text] cuprate superconductors has been widely observ
Externí odkaz:
https://doaj.org/article/e88e18e3e1694d96b4fd661b3f9c2d80
Autor:
Qian Li, Jinpeng Bai, Yuxue Ma, Yu Sun, Wenbin Zhou, Zhaoying Wang, Zhi Zhou, Zhonghua Wang, Yanhua Chen, Zeper Abliz
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 14, Iss 7, Pp 100973- (2024)
Polygala tenuifolia, commonly known as Yuanzhi (YZ) in Chinese, has been shown to possess anti-insomnia properties. However, the material basis and the mechanism underlying its sedative-hypnotic effects remain unclear. Herein, we investigated the act
Externí odkaz:
https://doaj.org/article/c3152af0716d43d2890cfdc5984e243b
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 13, Iss 8, Pp 851-861 (2023)
Tumors are spatially heterogeneous tissues that comprise numerous cell types with intricate structures. By interacting with the microenvironment, tumor cells undergo dynamic changes in gene expression and metabolism, resulting in spatiotemporal varia
Externí odkaz:
https://doaj.org/article/35740b452582448480e62c512e53619f
Publikováno v:
Applied Sciences, Vol 14, Iss 17, p 8013 (2024)
In this study, a single-outer-spiral electrode with inductance of 20 μH is employed to couple the energy input of a bipolar nanosecond pulse for the purpose of generating a large-scale atmospheric pressure plasma jet. When the spiral electrode is wr
Externí odkaz:
https://doaj.org/article/c563530acaf849a2a779a702fbe3524a