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Autor:
Tigran K Davtyan, Armen V Gyulkhandanyan, Yuri T Alexanyan, Lia A Avanessian, Spartac S Gambarov
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1297:182-190
The influence of adriamycin (ADR) and ADR complexes with transitional metals Fe2+, Cu2+ and Co2+ on Ca(2+)-dependent K+ channels of human erythrocytes was investigated. We show that the anthracycline moiety of ADR increases Ca(2+)-dependent K+ efflux