Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Spandana Naldiga"'
Autor:
Aysegul Ors, Alex Daniel Chitsazan, Aaron Reid Doe, Ryan M Mulqueen, Cigdem Ak, Yahong Wen, Syber Haverlack, Mithila Handu, Spandana Naldiga, Joshua C Saldivar, Hisham Mohammed
Publikováno v:
Nucleic Acids Research. 50:11492-11508
Breast cancers are known to be driven by the transcription factor estrogen receptor and its ligand estrogen. While the receptor's cis-binding elements are known to vary between tumors, heterogeneity of hormone signaling at a single-cell level is unkn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94c80d95c4fc8fe7696044752c46ea05
https://doi.org/10.1093/nar/gkac908
https://doi.org/10.1093/nar/gkac908
Publikováno v:
Chemical Research in Toxicology. 33:1997-2005
The environmental pollutant 6-nitrochrysene (6-NC) is a potent mutagen and a mammary carcinogen in rats. 6-NC is the most potent carcinogen ever tested in the newborn mouse assay. In mammalian cell...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1c3cd3d61ca512ce5eef02019025f51
https://doi.org/10.1021/acs.chemrestox.0c00197
https://doi.org/10.1021/acs.chemrestox.0c00197
Autor:
Claudia M. Nicolae, George Lucian Moldovan, Jenna Thomforde, Zhongtao Zhang, Natalia Y. Tretyakova, Shaofei Ji, Marietta Y.W.T. Lee, Spandana Naldiga, Ashis K. Basu
Publikováno v:
J Biol Chem
DNA-protein cross-links can interfere with chromatin architecture, block DNA replication and transcription, and interfere with DNA repair. Here we synthesized a DNA 23-mer containing a site-specific DNA-peptide cross-link (DpC) by cross-linking an 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5f25997bfcc9355f8838a39f37a7760
https://doi.org/10.1074/jbc.ra119.008879
https://doi.org/10.1074/jbc.ra119.008879
Publikováno v:
Chemical research in toxicology. 33(7)
The environmental pollutant 6-nitrochrysene (6-NC) is a potent mutagen and a mammary carcinogen in rats. 6-NC is the most potent carcinogen ever tested in the newborn mouse assay. In mammalian cells, it is metabolically activated by nitroreduction an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ee1bbe0fef9980119108b8487b4297a9
https://pubmed.ncbi.nlm.nih.gov/32551527
https://pubmed.ncbi.nlm.nih.gov/32551527
Tandem DNA lesions, containing two contiguously damaged nucleotides, are commonly formed by ionizing radiation. Their effects on replication in mammalian cells are largely unknown. Replication of isolated 2-deoxyribonolactone (L) and thymine glycol (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b495fe7102821cf63a6f186e746322e3
https://europepmc.org/articles/PMC7003646/
https://europepmc.org/articles/PMC7003646/
Autor:
Benjamin J. Ryan, Haozhe Yang, Brent V. Powell, Bret D. Freudenthal, Ashis K. Basu, Jan Henric T. Bacurio, Marc M. Greenberg, Spandana Naldiga
Publikováno v:
DNA Repair (Amst)
Fapy•dG and 8-OxodGuo are formed in DNA from a common N7-dG radical intermediate by reaction with hydroxyl radical. Although cellular levels of Fapy•dG are often greater, its effects on replication are less well understood than those of 8-OxodGuo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99914fff4508f4e77341cc881683371b
https://doi.org/10.1016/j.dnarep.2021.103213
https://doi.org/10.1016/j.dnarep.2021.103213
Autor:
Shaofei, Ji, Iwen, Fu, Spandana, Naldiga, Hongzhao, Shao, Ashis K, Basu, Suse, Broyde, Natalia Y, Tretyakova
Publikováno v:
Nucleic Acids Research
5-Formylcytosine (5fC) is an epigenetic DNA modification introduced via TET protein-mediated oxidation of 5-methyl-dC. We recently reported that 5fC form reversible DNA–protein conjugates (DPCs) with histone proteins in living cells (Ji et al. (201
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2023ea16d9ca51aa2e71f1d1d356f1fc
https://pubmed.ncbi.nlm.nih.gov/29905846
https://pubmed.ncbi.nlm.nih.gov/29905846
Autor:
Suse Broyde, Hongzhao Shao, Ashis K. Basu, Natalia Y. Tretyakova, Spandana Naldiga, Shaofei Ji, Iwen Fu
Publikováno v:
Nucleic Acids Research
5-Formylcytosine (5fC) is an epigenetic DNA modification introduced via TET protein-mediated oxidation of 5-methyl-dC. We recently reported that 5fC form reversible DNA-protein conjugates (DPCs) with histone proteins in living cells (Ji et al. (2017)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b60da240bc8b09f6bfa00a833b38b94
https://pubmed.ncbi.nlm.nih.gov/30184121
https://pubmed.ncbi.nlm.nih.gov/30184121