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pro vyhledávání: '"Spalding, D J M"'
Autor:
Huntjens, D R H, Strougo, A, Chain, A, Metcalf, A, Summerfield, S, Spalding, D J M, Danhof, M, Pasqua, O Della
Enterohepatic recirculation (EHC) is a common pharmacokinetic phenomenon that has been poorly modelled in animals. The presence of EHC leads to the appearance of multiple peaks in the concentration-time profile and increased exposure, which may have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::33111c690eb386414ad6626ab8cdee61
https://europepmc.org/articles/PMC2267282/
https://europepmc.org/articles/PMC2267282/
Autor:
Huntjens, D. R. H., Strougo, A., Chain, A., Metcalf, A., Summerfield, S., Spalding, D. J. M., Danhof, M., Della Pasqua, O.
Publikováno v:
British Journal of Pharmacology; Mar2008, Vol. 153 Issue 5, p1072-1084, 13p, 1 Diagram, 2 Charts, 5 Graphs
Autor:
Spalding, D. J. M.
The mechanism of the hydralazine/propranolol pharmacokinetic interaction was investigated using the rat as an animal model. Hydralazine infused intraportally, either 15 minutes prior to, or concurrently with propranolol, caused a 2-fold and 4-fold in
Externí odkaz:
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.593490