Chloroquine diphosphate in two different dosages as adjunctive therapy of hospitalized patients with severe respiratory syndrome in the context of coronavirus (SARS-CoV-2) infection: Preliminary safety results of a randomized, double-blinded, phase IIb clinical trial (CloroCovid-19 Study)

Autor: R. Pinto, Fernando Fonseca Almeida Val, Jose Diego Brito-Sousa, Julio Croda, Gustavo Adolfo Sierra Romero, Fundação de Vigilância em Saúde do Amazonas. Manaus, Am, Brasil., Marcus Lacerda, Quique Bassat, Marcus Vinitius de Farias Guerra, Marcelo A M Brito, Alexandre Vargas Schwarzbold, Mariana Simão Xavier, Spain Icrea. Barcelona, CloroCovid Team, Djane Clarys Baia-da-Silva, Mozambique Centro de Investigação em Saúde de Manhiça. Maputo, Márcia A. A. Alexandre, Vanderson de Souza Sampaio, Wuelton Marcelo Monteiro, Bernardino Cláudio de Albuquerque, Alexandre Salomão, Gisely Cardoso de Melo, Felipe Gomes Naveca, Maurício Lacerda Nogueira, André M. Siqueira, Cláudio Tadeu Daniel-Ribeiro, Maria Paula Gomes Mourão, Antônio Alcirley da Silva Balieiro, Ludhmila Abrahão Hajjar, Mayla Gabriela Silva Borba, Cor Jesus Fernandes Fontes

SummaryBackgroundThere is no specific antiviral therapy recommended for the disease caused by SARS-CoV-2 (COVID-19). Recent publications have drawn attention to the possible benefit of chloroquine (CQ). Our study aimed to comprehensively evaluate the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2e78a05cf3cadfd4efb6955fe2c5ee8
https://doi.org/10.1101/2020.04.07.20056424

Hollow metal nanostructures for enhanced plasmonics: synthesis, local plasmonic properties and applications

Autor: Institut Català de la Salut, [Genç A] Catalan Institute of Nanoscience and Nanotechnology, Barcelona, Spain. The Barcelona Institute of Science and Technology (BIST), Campus UAB, Bellaterra, Barcelona, Spain. Department of Metallurgy and Materials Engineering, Faculty of Engineering, Bartin University, Bartin, Turkey. [Patarroyo J] Catalan Institute of Nanoscience and Nanotechnology Barcelona, Spain. The Barcelona Institute of Science and Technology, Campus UAB, Bellaterra, Barcelona, Spain. [Sancho-Parramon J] Rudjer Boskovic Institute, Zagreb, Croatia. [Bastús N G] Catalan Institute of Nanoscience and Nanotechnology, Barcelona, Spain. The Barcelona Institute of Science and Technology (BIST), Campus UAB, Bellaterra, Barcelona, Spain. [Franco V] Catalan Institute of Nanoscience and Nanotechnology, Barcelona, Spain. The Barcelona Institute of Science and Technology (BIST), Campus UAB, Bellaterra, Barcelona, Spain. Vall d’Hebron Institut de Recerca, Barcelona, Spain. ICREA, Barcelona, Spain. [Arbiol J] Catalan Catalan Institute of Nanoscience and Nanotechnology, Barcelona, Spain. The Barcelona Institute of Science and Technology (BIST), Campus UAB, Bellaterra, Barcelona, Spain. ICREA, Barcelona, Spain., Hospital Universitari Vall d'Hebron

Publikováno v: Scientia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______272::d98c69cfe839667e01e8a2b95318e81c
https://hdl.handle.net/2072/433753

Heterogeneous Rate Constant for Amorphous Silica Nanoparticle Adsorption on Phospholipid Monolayers

Autor: Alex Vakurov, Rik Drummond-Brydson, Nicola William, Didem Sanver, Neus Bastús, Oscar H. Moriones, V. Puntes, Andrew L. Nelson

Publikováno v: Scientia

The interaction of amorphous silica nanoparticles with phospholipid monolayers and bilayers has received a great deal of interest in recent years and is of importance for assessing potential cellular toxicity of such species, whether natural or synth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71a056df1b8aa1651c4ac0b783d9f40a
https://doi.org/10.1021/acs.langmuir.1c03155

False Lumen Flow Patterns and their Relation with Morphological and Biomechanical Characteristics of Chronic Aortic Dissections. Computational Model Compared with Magnetic Resonance Imaging Measurements

Autor: Institut Català de la Salut, [Rudenick PA] Physense, Universitat Pompeu Fabra, Barcelona, Spain. Hospital Universitari Vall d'Hebron, Barcelona, Spain. Vall d’Hebron Institut de Recerca, Barcelona, Spain. Universitat Autònoma de Barcelona, Barcelona, Spain. [Segers P] Biofluid, Tissue and Solid Mechanics for Medical Applications, Institute Biomedical Technology, Ghent University, Ghent, Belgium. [Pineda V, Cuellar H, García-Dorado D, Evangelista A] Hospital Universitari Vall d'Hebron, Barcelona, Spain. Vall d’Hebron Institut de Recerca, Barcelona, Spain. Universitat Autònoma de Barcelona, Barcelona, Spain. [Bijnens BH] Physense, Universitat Pompeu Fabra, Barcelona, Spain. ICREA, Barcelona, Spain., Hospital Universitari Vall d'Hebron

Publikováno v: Scientia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______272::7c121355789a34ae4c02a175aef6a522
https://hdl.handle.net/2072/433801

Development of pathogenicity predictors specific for variants that do not comply with clinical guidelines for the use of computational evidence

Autor: Elena Álvarez de la Campa, Natalia Padilla, Xavier de la Cruz

Publikováno v: BMC Genomics, Vol 18, Iss S5, Pp 1-14 (2017)
BMC Genomics
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Digital.CSIC. Repositorio Institucional del CSIC
instname
Scientia

[Background] Strict guidelines delimit the use of computational information in the clinical setting, due to the still moderate accuracy of in silico tools. These guidelines indicate that several tools should always be used and that full coincidence b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2679ae219c631a5c149be966643b3f81
http://link.springer.com/article/10.1186/s12864-017-3914-0