Reduction of SPARC protects mice against NLRP3 inflammasome activation and obesity.

Autor: Ryu S; Department of Pathology and.; Department of Immunobiology, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Pharmacology, College of Medicine, Hallym University, Chuncheon, Gangwon, South Korea., Spadaro O; Department of Pathology and.; Department of Immunobiology, Yale School of Medicine, New Haven, Connecticut, USA., Sidorov S; Department of Pathology and.; Department of Immunobiology, Yale School of Medicine, New Haven, Connecticut, USA., Lee AH; Department of Pathology and.; Department of Immunobiology, Yale School of Medicine, New Haven, Connecticut, USA., Caprio S; Department of Pediatrics, Yale School of Medicine, New Haven, Connecticut, USA., Morrison C; Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA., Smith SR; Translational Research Institute for Metabolism and Diabetes, AdventHealth, Orlando, Florida, USA., Ravussin E; Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA., Shchukina I; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA., Artyomov MN; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA., Youm YH; Department of Pathology and.; Department of Immunobiology, Yale School of Medicine, New Haven, Connecticut, USA., Dixit VD; Department of Pathology and.; Department of Immunobiology, Yale School of Medicine, New Haven, Connecticut, USA.; Yale Center for Research on Aging, Yale School of Medicine, New Haven, Connecticut, USA.

Publikováno v: The Journal of clinical investigation [J Clin Invest] 2023 Oct 02; Vol. 133 (19). Date of Electronic Publication: 2023 Oct 02.

IL-27 signalling promotes adipocyte thermogenesis and energy expenditure.

Autor: Wang Q; Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment, Zhuhai Institute of Translational Medicine, Zhuhai People's Hospital Affiliated with Jinan University, Jinan University, Zhuhai, China.; The Biomedical Translational Research Institute, Faculty of Medical Science, Jinan University, Guangzhou, China., Li D; Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment, Zhuhai Institute of Translational Medicine, Zhuhai People's Hospital Affiliated with Jinan University, Jinan University, Zhuhai, China.; The Biomedical Translational Research Institute, Faculty of Medical Science, Jinan University, Guangzhou, China., Cao G; Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment, Zhuhai Institute of Translational Medicine, Zhuhai People's Hospital Affiliated with Jinan University, Jinan University, Zhuhai, China.; The Biomedical Translational Research Institute, Faculty of Medical Science, Jinan University, Guangzhou, China., Shi Q; Department of Endocrine, The First Affiliated Hospital, Jinan University, Guangzhou, China., Zhu J; Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment, Zhuhai Institute of Translational Medicine, Zhuhai People's Hospital Affiliated with Jinan University, Jinan University, Zhuhai, China.; The Biomedical Translational Research Institute, Faculty of Medical Science, Jinan University, Guangzhou, China., Zhang M; Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment, Zhuhai Institute of Translational Medicine, Zhuhai People's Hospital Affiliated with Jinan University, Jinan University, Zhuhai, China.; The Biomedical Translational Research Institute, Faculty of Medical Science, Jinan University, Guangzhou, China., Cheng H; Key Laboratory for the Genetics of Developmental & Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, Shanghai, China., Wen Q; Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment, Zhuhai Institute of Translational Medicine, Zhuhai People's Hospital Affiliated with Jinan University, Jinan University, Zhuhai, China.; The Biomedical Translational Research Institute, Faculty of Medical Science, Jinan University, Guangzhou, China., Xu H; Department of Immunobiology, School of Medicine, Yale University, New Haven, CT, USA., Zhu L; The Biomedical Translational Research Institute, Faculty of Medical Science, Jinan University, Guangzhou, China.; The First Affiliated Hospital, Faculty of Medical Science, Jinan University, Guangzhou, China., Zhang H; Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment, Zhuhai Institute of Translational Medicine, Zhuhai People's Hospital Affiliated with Jinan University, Jinan University, Zhuhai, China.; The Biomedical Translational Research Institute, Faculty of Medical Science, Jinan University, Guangzhou, China., Perry RJ; Department of Medicine, School of Medicine, Yale University, New Haven, CT, USA.; Department of Cellular & Molecular Physiology, School of Medicine, Yale University, New Haven, CT, USA., Spadaro O; Department of Immunobiology, School of Medicine, Yale University, New Haven, CT, USA.; Department of Comparative Medicine, School of Medicine, Yale University, New Haven, CT, USA., Yang Y; Department of Comparative Medicine, School of Medicine, Yale University, New Haven, CT, USA., He S; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Institute for Advanced Studies, Wuhan University, Wuhan, China., Chen Y; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Institute for Advanced Studies, Wuhan University, Wuhan, China., Wang B; Tsinghua Berkeley Shenzhen Institute (TBSI), Tsinghua University, Shenzhen, China., Li G; The Biomedical Translational Research Institute, Faculty of Medical Science, Jinan University, Guangzhou, China.; The First Affiliated Hospital, Faculty of Medical Science, Jinan University, Guangzhou, China., Liu Z; Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment, Zhuhai Institute of Translational Medicine, Zhuhai People's Hospital Affiliated with Jinan University, Jinan University, Zhuhai, China.; The Biomedical Translational Research Institute, Faculty of Medical Science, Jinan University, Guangzhou, China., Yang C; Department of Endocrine, The Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan People's Hospital, Qingyuan, China., Wu X; School of Life Sciences, Tianjin University, Tianjin, China., Zhou L; Guangdong-Hong Kong-Macau Institute of CNS Regeneration, Ministry of Education CNS Regeneration Collaborative Joint Laboratory, Jinan University, Guangzhou, China., Zhou Q; Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment, Zhuhai Institute of Translational Medicine, Zhuhai People's Hospital Affiliated with Jinan University, Jinan University, Zhuhai, China.; The Biomedical Translational Research Institute, Faculty of Medical Science, Jinan University, Guangzhou, China., Ju Z; Key Laboratory of Regenerative Medicine of Ministry of Education, Institute of Aging and Regenerative Medicine, Jinan University, Guangzhou, China., Lu H; Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment, Zhuhai Institute of Translational Medicine, Zhuhai People's Hospital Affiliated with Jinan University, Jinan University, Zhuhai, China., Xin Y; Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment, Zhuhai Institute of Translational Medicine, Zhuhai People's Hospital Affiliated with Jinan University, Jinan University, Zhuhai, China., Yang X; Department of Cellular & Molecular Physiology, School of Medicine, Yale University, New Haven, CT, USA.; Department of Comparative Medicine, School of Medicine, Yale University, New Haven, CT, USA., Wang C; Department of Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China., Liu Y; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Institute for Advanced Studies, Wuhan University, Wuhan, China., Shulman GI; Department of Medicine, School of Medicine, Yale University, New Haven, CT, USA.; Department of Cellular & Molecular Physiology, School of Medicine, Yale University, New Haven, CT, USA., Dixit VD; Department of Immunobiology, School of Medicine, Yale University, New Haven, CT, USA.; Department of Comparative Medicine, School of Medicine, Yale University, New Haven, CT, USA., Lu L; Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment, Zhuhai Institute of Translational Medicine, Zhuhai People's Hospital Affiliated with Jinan University, Jinan University, Zhuhai, China. lu_ligong@163.com., Yang H; Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment, Zhuhai Institute of Translational Medicine, Zhuhai People's Hospital Affiliated with Jinan University, Jinan University, Zhuhai, China. hengwenyang@jnu.edu.cn.; The Biomedical Translational Research Institute, Faculty of Medical Science, Jinan University, Guangzhou, China. hengwenyang@jnu.edu.cn., Flavell RA; Department of Immunobiology, School of Medicine, Yale University, New Haven, CT, USA. richard.flavell@yale.edu., Yin Z; Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment, Zhuhai Institute of Translational Medicine, Zhuhai People's Hospital Affiliated with Jinan University, Jinan University, Zhuhai, China. tzhinan@jnu.edu.cn.; The Biomedical Translational Research Institute, Faculty of Medical Science, Jinan University, Guangzhou, China. tzhinan@jnu.edu.cn.

Publikováno v: Nature [Nature] 2021 Dec; Vol. 600 (7888), pp. 314-318. Date of Electronic Publication: 2021 Nov 24.

The Phytochemical Profile of the Petroleum Ether Extract of Purslane Leaves and Its Anticancer Effect on 4-(Methylnitrosamino)-1-(3-pyridyl)-1-buta-4 None (NNK)-Induced Lung Cancer in Rats.

Autor: Abd Elkarim, Asmaa S.¹ (AUTHOR) asmaa_nrc@yahoo.com, Mohamed, Safaa H.² (AUTHOR) rise_sun_1982@hotmail.com, Ali, Naglaa A.² (AUTHOR) almardeyah@gmail.com, Elsayed, Ghada H.^2,3 (AUTHOR) ghadanrc@yahoo.com, Aly, Mohamed S.⁴ (AUTHOR) mohamedaly_nrc@yahoo.com, Elgamal, Abdelbaset M.⁵ (AUTHOR) algamalgene@yahoo.com, Elsayed, Wael M.⁶ (AUTHOR) waelmatar@hotmail.com, El-Newary, Samah A.⁷ (AUTHOR) sa.el-newary@nrc.sci.eg

Publikováno v: International Journal of Molecular Sciences. Dec2024, Vol. 25 Issue 23, p13024. 41p.

Aging human abdominal subcutaneous white adipose tissue at single cell resolution.

Autor: Whytock, K. L.¹ (AUTHOR), Divoux, A.¹ (AUTHOR), Sun, Y.² (AUTHOR), Pino, M. F.¹ (AUTHOR), Yu, G.¹ (AUTHOR), Jin, C. A.³ (AUTHOR), Robino, J. J.⁴ (AUTHOR), Plekhanov, A.⁴ (AUTHOR), Varlamov, O.⁴ (AUTHOR), Smith, S. R.¹ (AUTHOR), Walsh, M. J.² (AUTHOR), Sparks, L. M.¹ (AUTHOR) lauren.sparks@adventhealth.com

Publikováno v: Aging Cell. Nov2024, Vol. 23 Issue 11, p1-18. 18p.

Functional analysys of the Pax8 promoter reveals autoregulation and the presence of a novel thyroid-specific DNA binding activity

Autor: di Gennaro A1, Spadaro O, Baratta MG, De Felice M, Di Lauro R.

Publikováno v: Thyroid (N.Y.N.Y.) (2013).
info:cnr-pdr/source/autori:di Gennaro A1, Spadaro O, Baratta MG, De Felice M, Di Lauro R./titolo:Functional analysys of the Pax8 promoter reveals autoregulation and the presence of a novel thyroid-specific DNA binding activity./doi:/rivista:Thyroid (N.Y.N.Y.)/anno:2013/pagina_da:/pagina_a:/intervallo_pagine:/volume

BACKGROUND: Organogenesis of the thyroid gland requires the Pax8 protein. Absence or reduction of Pax8 results in congenital hypothyroidism in animal models and humans, respectively. This study aims at elucidating the regulatory mechanism leading to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::5613a53242301e042a4c710f8ee72bb0
http://www.cnr.it/prodotto/i/347920