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469 Heterozygosity of UPR Repressor Grp78 Reduces Intestinal Stem Cell Regeneration Potential and Protects Against Adenoma Formation

Autor: van Lidth de Jeude, Jooske F., Meijer, Bartolomeus J., Spaan, Claudia N., Wielenga, Mattheus C., Muncan, Vanesa, van den Brink, Gijs, Heijmans, Jarom

Publikováno v: In Gastroenterology April 2016 150(4) Supplement 1:S103-S103

Heterozygosity of Chaperone Grp78 Reduces Intestinal Stem Cell Regeneration Potential and Protects against Adenoma Formation.

Autor: van Lidth de Jeude JF; Department of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, University of Amsterdam, Amsterdam, the Netherlands., Spaan CN; Department of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, University of Amsterdam, Amsterdam, the Netherlands., Meijer BJ; Department of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, University of Amsterdam, Amsterdam, the Netherlands., Smit WL; Department of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, University of Amsterdam, Amsterdam, the Netherlands., Soeratram TTD; Department of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, University of Amsterdam, Amsterdam, the Netherlands., Wielenga MCB; Department of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, University of Amsterdam, Amsterdam, the Netherlands., Westendorp BF; Department of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, University of Amsterdam, Amsterdam, the Netherlands., Lee AS; Department of Biochemistry and Molecular Medicine, USC/Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, Los Angeles, California., Meisner S; Department of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, University of Amsterdam, Amsterdam, the Netherlands., Vermeulen JLM; Department of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, University of Amsterdam, Amsterdam, the Netherlands., Wildenberg ME; Department of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, University of Amsterdam, Amsterdam, the Netherlands., van den Brink GR; Department of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, University of Amsterdam, Amsterdam, the Netherlands., Muncan V; Department of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, University of Amsterdam, Amsterdam, the Netherlands., Heijmans J; Department of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, University of Amsterdam, Amsterdam, the Netherlands. j.heijmans@amc.nl.; Department of Internal Medicine, University of Amsterdam, Amsterdam, the Netherlands.

Publikováno v: Cancer research [Cancer Res] 2018 Nov 01; Vol. 78 (21), pp. 6098-6106. Date of Electronic Publication: 2018 Sep 19.