Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Soyoung Son"'
Autor:
Jung Min Shin, Chan‐Hyeong Lee, Soyoung Son, Chan Ho Kim, Jae Ah Lee, Hyewon Ko, Sol Shin, Seok Ho Song, Seong‐Sik Park, Ju‐Hyun Bae, Ju‐Mi Park, Eun‐Ji Choe, Moon‐Chang Baek, Jae Hyung Park
Publikováno v:
Advanced Science, Vol 9, Iss 5, Pp n/a-n/a (2022)
Abstract Despite their potent antitumor activity, clinical application of immune checkpoint inhibitors has been significantly limited by their poor response rates (
Externí odkaz:
https://doaj.org/article/47f461ab66a04e4d8a5b2484253a2d2c
Autor:
Sol Shin, Hyewon Ko, Chan Ho Kim, Bo Kyeong Yoon, Soyoung Son, Jae Ah Lee, Jung Min Shin, Jeongjin Lee, Seok Ho Song, Joshua A. Jackman, Jae Hyung Park
Publikováno v:
Nature Materials. 22:656-665
Autor:
Yongeun Cho, Jung Min Shin, Soyoung Son, Dong-Gyu Jo, Sol Shin, Hyewon Ko, Eun Sook Lee, Jae Hyung Park, Sunyoung Park, Hark Kyun Kim, Jeongmi Lee, Jae Ah Lee, Jae Hoon Sul
Publikováno v:
Acta Biomaterialia. 128:462-473
Although tolerogenic dendritic cell-derived exosomes (TolDex) have emerged as promising therapeutics for rheumatoid arthritis (RA), their clinical applications have been hampered by their poor in vivo disposition after systemic administration. Herein
Autor:
Van Dat Bui, Soyoung Son, Wilbin Xavier, Van Quy Nguyen, Jae Min Jung, Jungmi Lee, Sol Shin, Wooram Um, Jae Yoon An, Chan Ho Kim, Yeari Song, Yuce Li, Jae Hyung Park
Publikováno v:
Biomaterials. 287
Extracellular vesicles (EVs) have shown great potential in disease diagnosis and treatment; however, their clinical applications remain challenging due to their unsatisfactory long-term stability and the lack of effective delivery strategies. In this
Autor:
Jeongyun Kim, Jae Ah Lee, Sol Shin, Jung Min Shin, Eun Sook Lee, Chan Ho Kim, Jae Min Jung, Soyoung Son, Jae Hyung Park, Hyewon Ko
Publikováno v:
Biomaterials. 276
Immune checkpoint therapy (ICT), which reinvigorates cytotoxic T cells, provides clinical benefits as an alternative to conventional cancer therapies. However, its clinical response rate is too low to treat an immune-excluded tumor, owing to the pres
Publikováno v:
Biomaterials. 282:121412
Therapeutic cancer vaccines have attracted attention because of their potential to prime cytotoxic T cells, which are highly antigen (Ag)-specific, allowing personalized cancer immunotherapy. However, because of their low immunogenicity, cancer vacci
Autor:
Doo Sung Lee, Jueun Jeon, Sol Shin, V. G. Deepagan, Eun Sook Lee, Minah Suh, Wooram Um, Soyoung Son, Hyewon Ko, Jae Hyung Park, Jiwoong Min, Seunglee Kwon
Publikováno v:
Acta Biomaterialia. 79:294-305
Since delivering drugs to an entire tumoral region leads to high therapeutic efficacy and good prognosis, achieving deep tumoral penetration of drugs is a major issue in cancer treatment. In this regard, conventional nanomedicines (50 nm) have shown
Autor:
Sol Shin, Seunglee Kwon, Soyoung Son, Jae Hyung Park, Hyewon Ko, Wooram Um, Jueun Jeon, V. G. Deepagan, Jun Young Lee, N. Vijayakameswara Rao
Publikováno v:
International Journal of Biological Macromolecules. 110:406-415
Trop2, a transmembrane glycoprotein, has emerged as a biomarker for targeted cancer therapy since it is overexpressed in 80% of triple negative breast cancer (TNBC) patients. For the site-specific delivery of the anticancer drug into TNBC, anti-Trop2
Autor:
Thavasyappan Thambi, Jueun Jeon, N. Vijayakameswara Rao, Sol Shin, Van Quy Nguyen, Soyoung Son, Hyewon Ko, Jae Hyung Park, Hwa Seung Han, Yung Doug Suh
Publikováno v:
International Journal of Biological Macromolecules. 110:399-405
In an attempt to develop the hypoxia-responsive nanoparticles for cancer therapy, a polymer conjugate, consisting of carboxymethyl dextran (CMD) and black hole quencher 3 (BHQ3), was prepared. The polymer conjugate can self-assemble into nanoparticle
Autor:
Jung Min Shin, Chan‐Hyeong Lee, Soyoung Son, Chan Ho Kim, Jae Ah Lee, Hyewon Ko, Sol Shin, Seok Ho Song, Seong‐Sik Park, Ju‐Hyun Bae, Ju‐Mi Park, Eun‐Ji Choe, Moon‐Chang Baek, Jae Hyung Park
Publikováno v:
Advanced Science, Vol 9, Iss 5, Pp n/a-n/a (2022)
Despite their potent antitumor activity, clinical application of immune checkpoint inhibitors has been significantly limited by their poor response rates (