Výsledky vyhledávání - "Soydan Dogan"

Downregulation of Rab25 activates Akt1 in head and neck squamous cell carcinoma

Autor: Didem Seven, Nur Buyru, Erkan Kilic, Soydan Dogan, Emin Karaman, Hikmet Koseoglu

Several studies have suggested that Ras-associated binding 25 protein (Rab25) is involved in the pathogenesis of human cancer. Although it has been demonstrated that the development of head and neck squamous cell carcinoma (HNSCC) is the result of an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e435840488f5e2cbb8c8674b2e1856e2
https://europepmc.org/articles/PMC4533719/

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The effect of LKB1 on the PI3K/Akt pathway activation in association with PTEN and PIK3CA in HNC

Autor: Damla Ulker, Seda Ekizoglu, Emin Karaman, Soydan Dogan, Emine Deniz Gözen, Nur Buyru, Didem Seven

Publikováno v: Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-LaryngologyCervico-Facial Surgery. 40(6)

Objective PI3K/Akt signalling pathway is frequently activated in several types of cancer. However, activator molecules have not been analysed systematically in HNSCC. The aim of this study was to investigate upstream activators and inhibitors of this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eef8e71d71dd2087745077a815e5db4a
https://pubmed.ncbi.nlm.nih.gov/25850957

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Abstract A14: LKB1 loss is associated with Akt1 phosphorylation in head and neck cancer

Autor: Nejat Dalay, Seda Ekizoglu, Damla Ulker, Soydan Dogan, Nur Buyru, Emin Karaman

Publikováno v: Molecular Cancer Therapeutics. 14:A14-A14

Head and neck cancer is a multifactorial disease including a group of biologically similar cancers and representing 3% of all malignant tumors. Its incidence has been rising in the last years with more than half a million cases and leading to 300 000

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::96b1d0eca34209438ad104a8a14b608f
https://doi.org/10.1158/1538-8514.pi3k14-a14

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Abstract A25: Effect of Rab25 on Akt1 phosphorylation

Autor: Hikmet Koseoglu, Soydan Dogan, Nur Buyru, Didem Seven, Emin Karaman

Publikováno v: Molecular Cancer Therapeutics. 14:A25-A25

Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous disease and despite therapeutic improvements and reconstructive modalities, the overall survival rate remains relatively poor. Although, tobacco and alcohol consumption are recognized a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1a9567676f29f5c8339d9c634bf8ecc8
https://doi.org/10.1158/1538-8514.pi3k14-a25

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