Zobrazeno 1 - 10
of 450
pro vyhledávání: '"Sox17"'
Autor:
Daichi Kodama, Motoki Takenaka, Chiemi Saigo, Masako Azuma, Yuki Hanamatsu, Masanori Isobe, Tamotsu Takeuchi
Publikováno v:
Journal of Ovarian Research, Vol 17, Iss 1, Pp 1-9 (2024)
Abstract Recent studies have revealed that the Sry-related HMG box gene 17 (SOX17) plays an important role in ovarian carcinogenesis. Unlike other types of ovarian cancer, ovarian clear cell carcinoma (OCCC) has a distinct pathobiological phenotype,
Externí odkaz:
https://doaj.org/article/4ec6e70f56cb410595753ad7e2517d24
Publikováno v:
Thoracic Cancer, Vol 15, Iss 32, Pp 2319-2326 (2024)
Abstract Introduction Sex‐determining region Y‐related high‐mobility group box 17 protein (SOX17), a proangiogenic transcription factor, is specifically expressed in tumor endothelial cells (TECs) of implanted Lewis lung carcinoma. However, the
Externí odkaz:
https://doaj.org/article/3efb8e5db128490e9b742b9cdf31de27
Autor:
Hong Gao, Saliha Pathan, Beverly R. E. A. Dixon, Aarthi Pugazenthi, Megumi Mathison, Tamer M.A. Mohamed, Todd K. Rosengart, Jianchang Yang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Cardiac cellular fate transition holds remarkable promise for the treatment of ischemic heart disease. We report that overexpressing two transcription factors, Sall4 and Gata4, which play distinct and overlapping roles in both pluripotent st
Externí odkaz:
https://doaj.org/article/dddb22f9f6054e26a9612826b2a513e0
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-24 (2024)
Abstract Background Abnormalities of in utero testis development are strongly associated with reproductive health conditions, including male infertility and testis cancer. In mouse testes, SOX9 and FGF9 support Sertoli cell development, while VEGF si
Externí odkaz:
https://doaj.org/article/87033842ebcb4f02a0e3de5f29d5213a
Publikováno v:
Molecular Biomedicine, Vol 5, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/f3ae493f3ede450fa50500400a96718f
Publikováno v:
Shanghai Jiaotong Daxue xuebao. Yixue ban, Vol 43, Iss 10, Pp 1219-1226 (2023)
Objective·To explore the possible pathogenic gene of total anomalous pulmonary venous connection (TAPVC) by whole exon sequencing and verify its function.Methods·One hundred TAPVC children (case group) and one hundred and twenty healthy children (c
Externí odkaz:
https://doaj.org/article/02e6a46c332d4b9d9e8d65b3fbc2a9ad
Autor:
Gerel Melig, Ikuo Nobuhisa, Kiyoka Saito, Ryota Tsukahara, Ayumi Itabashi, Yoshiakira Kanai, Masami Kanai-Azuma, Mitsujiro Osawa, Motohiko Oshima, Atsushi Iwama, Tetsuya Taga
Publikováno v:
Inflammation and Regeneration, Vol 43, Iss 1, Pp 1-17 (2023)
Abstract Background During mouse embryonic development, definitive hematopoiesis is first detected around embryonic day (E) 10.5 in the aorta-gonad-mesonephros (AGM) region. Hematopoietic stem cells (HSCs) arise in the dorsal aorta’s intra-aortic h
Externí odkaz:
https://doaj.org/article/85816b709bcc4d1793f1959a6070ad8f
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Pulmonary arterial hypertension (PAH) is a progressive disease that is characterized by an obliterative vasculopathy of the distal pulmonary circulation. Despite significant progress in our understanding of the pathophysiology, currently approved med
Externí odkaz:
https://doaj.org/article/111b1355ea8245ef9e799113ca35e44f
Autor:
Chih-Hsiung Hsieh, Wen-Hui Kuan, Wei-Lun Chang, I-Ying Kuo, Hsun Liu, Dar-Bin Shieh, Hsuan Liu, Bertrand Tan, Yi-Ching Wang
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-20 (2022)
Abstract Background Esophageal squamous cell carcinoma (ESCC) is the sixth leading cause of cancer-associated death worldwide with a dismal overall 5-year survival rate of less than 20%. The standard first-line therapy for advanced ESCC is concomitan
Externí odkaz:
https://doaj.org/article/30217219feb34a9f871a60222942de23
Autor:
Ying-Yi Luo, Hui-Ying Jie, Ke-Jun Huang, Bing Cai, Xiu Zhou, Ming-Yi Liang, Can-Quan Zhou, Qing-Yun Mai
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundSOX17 has been identified as a critical factor in specification of human primordial germ cells, but whether SOX17 regulates development of germ cells after sex differentiation is poorly understood. MethodsWe collected specimens of gonadal r
Externí odkaz:
https://doaj.org/article/13e97844ce5b4189b1ceabe1d59d929b