Zobrazeno 1 - 10
of 3 041
pro vyhledávání: '"Sox10"'
Publikováno v:
Jichu yixue yu linchuang, Vol 44, Iss 11, Pp 1510-1515 (2024)
Objective To isolate and culture neural crest cells (NCCs) from lung tissue of mice and to identify the characteristics of the cells in order to provide a new cell model for studying lung injury and injure repair. Methods The mT/mG dual-fluorescence
Externí odkaz:
https://doaj.org/article/22dd010d28ac4254a14b33e7a0c599ab
Autor:
Lucia Martinkova, Pavlina Zatloukalova, Martina Kucerikova, Nela Friedlova, Zuzana Tylichova, Filip Zavadil-Kokas, Ted Robert Hupp, Philip John Coates, Borivoj Vojtesek
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-21 (2024)
Abstract Background PD-L1 expression on cancer cells is an important mechanism of tumor immune escape, and immunotherapy targeting the PD-L1/PD1 interaction is a common treatment option for patients with melanoma. However, many patients do not respon
Externí odkaz:
https://doaj.org/article/dd7c42a1c1ae4a469881435e5bda7846
Autor:
Gunadi, Verrell Christopher Amadeus, Fadila Dyah Trie Utami, Fiqih Vidiantoro Halim, Nabilah Anisa Novebri, Rahaditya Alrasyidi Hanggoro, Avinindita Nura Lestari, Kristy Iskandar, Andi Dwihantoro, Eko Purnomo
Publikováno v:
BMC Pediatrics, Vol 24, Iss 1, Pp 1-6 (2024)
Abstract Background HSCR is a complex genetic disorder characterized by the absence of ganglion cells in the intestine, leading to a functional obstruction. It is due to a disruption of complex signaling pathways within the gene regulatory network (G
Externí odkaz:
https://doaj.org/article/3e19677808b143549e5098eb37f6170c
Publikováno v:
Cancer Medicine, Vol 13, Iss 16, Pp n/a-n/a (2024)
Abstract Purpose Schwannoma is a rare mesenchymal tumor. In this study, we analyzed clinicopathologically 99 schwannomas.This retrospective study delves into the clinical, pathological, and immunohistochemical dimensions of abdominal schwannomas. Res
Externí odkaz:
https://doaj.org/article/665bd1dceab541f993fb26e7846b1c93
Autor:
Wenxin Yu, Maria Eleni Kastriti, Mohamed Ishan, Saurav Kumar Choudhary, Md Mamunur Rashid, Naomi Kramer, Hy Gia Truong Do, Zhonghou Wang, Ting Xu, Robert F. Schwabe, Kaixiong Ye, Igor Adameyko, Hong-Xiang Liu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
IntroductionWe have recently demonstrated that Sox10-expressing (Sox10+) cells give rise to mainly type-III neuronal taste bud cells that are responsible for sour and salt taste. The two tissue compartments containing Sox10+ cells in the surrounding
Externí odkaz:
https://doaj.org/article/ff875960f60a40848043ca42d5cf8e6c
Autor:
Yu Huang, Jia Geng, Yang Long, Wenyu Xiong, Lu Kang, Meilin Chen, Ting Tang, Mingjun Zhong, Fengxiao Bu, Yu Lu, Jing Cheng, Huijun Yuan
Publikováno v:
Frontiers in Audiology and Otology, Vol 2 (2024)
IntroductionWaardenburg syndrome (WS) is a genetic disorder characterized by hearing loss, hypopigmentation, and distinct facial features. Despite > 60% molecular diagnosis rate for WS patients, pathogenic variants within coding regions are predomina
Externí odkaz:
https://doaj.org/article/17eef314b5b24edeaeb3e2d38adeddb4
Autor:
Hisham F. Bahmad, Aran Thiravialingam, Karthik Sriganeshan, Jeffrey Gonzalez, Veronica Alvarez, Stephanie Ocejo, Alvaro R. Abreu, Rima Avellan, Alejandro H. Arzola, Sana Hachem, Robert Poppiti
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 12, Pp 10131-10158 (2023)
The embryonic development of neural crest cells and subsequent tissue differentiation are intricately regulated by specific transcription factors. Among these, SOX10, a member of the SOX gene family, stands out. Located on chromosome 22q13, the SOX10
Externí odkaz:
https://doaj.org/article/124159622bf0415a9f1f77c03c947356
Publikováno v:
陆军军医大学学报, Vol 45, Iss 24, Pp 2512-2520 (2023)
Objective To compare the otological phenotypic characteristics induced by Waardenburg syndrome mutation SOX10 p.R106W in mouse, miniature pig and human, and to construct a mouse model harboring orthologous human SOX10 p.R106W mutation. Methods By com
Externí odkaz:
https://doaj.org/article/86f1eaf2c6d448fa9a22edf8fc4d929e
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 12, Iss 3, Pp n/a-n/a (2024)
Abstract Objective To explore the molecular etiology of Waardenburg syndrome type II (WS2) in a family from Yunnan province, China. Methods A total of 406 genes related to hereditary hearing loss were sequenced using next‐generation sequencing. DNA
Externí odkaz:
https://doaj.org/article/6c14d1a1b5ba47dc95a4cd9f7a926c81
Publikováno v:
Journal of Islamic International Medical College, Vol 18, Iss 3, Pp 164-169 (2023)
Objective: To determine the frequency of SOX10 expression in patients with triple-negative breast cancer. Study Design:Descriptive cross-sectional study. Place and Duration of Study: Armed Forces Institute of Pathology, Combined Military Hospital, Ra
Externí odkaz:
https://doaj.org/article/0d1bf0cda39f42259adfb4e9ddf6009f