Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Sowmya Parameswaran"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Antibodies have been extensively used in numerous applications within proteomics-based technologies, requiring high sensitivity, specificity, a broad dynamic range for detection, and precise, reproducible quantification. Seeking alternatives
Externí odkaz:
https://doaj.org/article/71bad3de59ce4a39b35b6e617c9d4358
Autor:
Santosh Kumar Bikkarolla, Kavipriya Venkatesan, Yeddula Rebecca Revathy, Sowmya Parameswaran, Subramanian Krishnakumar, Dhananjaya Dendukuri
Publikováno v:
Biosensors, Vol 14, Iss 1, p 30 (2024)
A colloidal gold-based lateral flow immunoassay was developed for the rapid quantitative detection of Cystatin-C in serum and whole blood. This device has an assay time of 15 min, making it a convenient point-of-care diagnostic tool. The device has a
Externí odkaz:
https://doaj.org/article/2ffe16f0804948389f164d08d8f2c4ce
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Retinoblastoma (RB) is the most common paediatric intraocular tumour. The management of RB has improved the survival and vision with recent advances in the treatment. Improved therapeutic approaches focussing on targeting tumours and minimiz
Externí odkaz:
https://doaj.org/article/101a80d4eadf4db9879bf973b9390733
Autor:
Sivapriya Sivagurunathan, Lakshmi Dhevi N Selvan, Aafaque Ahmad Khan, Sowmya Parameswaran, Harsha Bhattacharjee, Krishna Gogoi, Harsha Gowda, T S Keshava Prasad, Akhilesh Pandey, S Ashok Kumar, Pukhraj Rishi, Ekta Rishi, Dhanashree Ratra, Muna Bhende, Narayanan Janakiraman, Jyotirmay Biswas, Subramanian Krishnakumar
Publikováno v:
Indian Journal of Ophthalmology, Vol 69, Iss 3, Pp 647-654 (2021)
Purpose: Age-related macular degeneration (AMD) is one of the leading causes of irreversible central vision loss in the elderly population. The current study aims to find non-invasive prognostic biomarkers in the urine specimens of the AMD patients.
Externí odkaz:
https://doaj.org/article/b6d55ab1c3c84e798cb4a66ff8c3c716
Autor:
Ambily Vincent, Vikas Khetan, Pukhraj Rishi, Ganesan Suganeswari, Subramanian Krishnakumar, Uma Maheswari Krishnan, Sowmya Parameswaran
Publikováno v:
Stem Cell Research, Vol 29, Iss , Pp 42-45 (2018)
Retinoblastoma (RB) is a pediatric intraocular tumor caused by mutations in retinoblastoma (RB1) gene. We have generated induced pluripotent stem cell line VRFi001-A from a bilateral retinoblastoma patient with heterozygous RB1 gene deletion. The iPS
Externí odkaz:
https://doaj.org/article/facbd12b8c7142faae6c7030cf1d5ef6
Autor:
Sushma Kalmodia, Sowmya Parameswaran, Kalaivani Ganapathy, Wenrong Yang, Colin J. Barrow, Jagat R. Kanwar, Kislay Roy, Madavan Vasudevan, Kirti Kulkarni, Sailaja V. Elchuri, Subramanian Krishnakumar
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 9, Iss C, Pp 349-364 (2017)
Inhibition of the interaction between p53 and HDM2 is an effective therapeutic strategy in cancers that harbor a wild-type p53 protein such as retinoblastoma (RB). Nanoparticle-based delivery of therapeutic molecules has been shown to be advantageous
Externí odkaz:
https://doaj.org/article/7be3f895edc3482eb78cfafd38b5f78f
Publikováno v:
Indian Journal of Ophthalmology, Vol 65, Iss 3, Pp 177-183 (2017)
Age-related macular degeneration (AMD) leads to progressive loss of central vision in the elderly. At a cellular level, there is aging of the retinal pigment epithelial (RPE) cells, and accumulation of lipofuscin that interferes with the proper funct
Externí odkaz:
https://doaj.org/article/00bc5f523e6e4e8d8e6ec71235b515de
Autor:
Vinay Kumar Aakalu, Sowmya Parameswaran, Mark Maienschein-Cline, Neil Bahroos, Dhara Shah, Marwan Ali, Subramanian Krishnakumar
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169346 (2017)
The study of human lacrimal gland biology and development is limited. Lacrimal gland tissue is damaged or poorly functional in a number of disease states including dry eye disease. Development of cell based therapies for lacrimal gland diseases requi
Externí odkaz:
https://doaj.org/article/4dd41ed99d0f43eda487910213fa7b25
Autor:
Carolina Beltrame Del Debbio, Qulsum Mir, Sowmya Parameswaran, Saumi Mathews, Xiaohuan Xia, Li Zheng, Andrew J Neville, Iqbal Ahmad
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152025 (2016)
Müller glia (MG), the sole glial cells generated by retinal progenitors, have emerged as a viable cellular target for therapeutic regeneration in degenerative blinding diseases, as they possess dormant stem cell properties. However, the mammalian MG
Externí odkaz:
https://doaj.org/article/8e784bbac7004561ab33f6249015406d
Autor:
Sowmya Parameswaran, Sudha Balasubramanian, Norbert Babai, Carolina B DelDebbio, Donald W Harms, Channabasavaiah B Gurumurthy, Mahendra S Rao, John G Sharp, Iqbal Ahmad
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46734 (2012)
Reprogramming somatic cells to a pluripotent state by nucleic acid based (NAB) approaches, involving the ectopic expression of transcription factors, has emerged as a standard method. We recently demonstrated that limbal progenitors that regenerate c
Externí odkaz:
https://doaj.org/article/9597cbe496414ecbb4a1321acbefc7ac