Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Sovitj Pou"'
Autor:
Marta G. Silva, Reginaldo G. Bastos, J. Stone Doggett, Michael K. Riscoe, Sovitj Pou, Rolf Winter, Rozalia A. Dodean, Aaron Nilsen, Carlos E. Suarez
Publikováno v:
Parasites & Vectors, Vol 13, Iss 1, Pp 1-11 (2020)
Abstract Background The most common apicomplexan parasites causing bovine babesiosis are Babesia bovis and B. bigemina, while B. caballi and Theileria equi are responsible for equine piroplasmosis. Treatment and control of these diseases are usually
Externí odkaz:
https://doaj.org/article/35a9dec597be472688855738dda6a7d7
Autor:
Martin J. Smilkstein, Sovitj Pou, Alina Krollenbrock, Lisa A. Bleyle, Rozalia A. Dodean, Lisa Frueh, David J. Hinrichs, Yuexin Li, Thomas Martinson, Myrna Y. Munar, Rolf W. Winter, Igor Bruzual, Samantha Whiteside, Aaron Nilsen, Dennis R. Koop, Jane X. Kelly, Stefan H. I. Kappe, Brandon K. Wilder, Michael K. Riscoe
Publikováno v:
Malaria Journal, Vol 18, Iss 1, Pp 1-17 (2019)
Abstract Background The potential benefits of long-acting injectable chemoprotection (LAI-C) against malaria have been recently recognized, prompting a call for suitable candidate drugs to help meet this need. On the basis of its known pharmacodynami
Externí odkaz:
https://doaj.org/article/630a94e7fc5a4c469f0ed0eacdad2650
Autor:
Hangjun Ke, Suresh M Ganesan, Swati Dass, Joanne M Morrisey, Sovitj Pou, Aaron Nilsen, Michael K Riscoe, Michael W Mather, Akhil B Vaidya
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0214023 (2019)
The battle against malaria has been substantially impeded by the recurrence of drug resistance in Plasmodium falciparum, the deadliest human malaria parasite. To counter the problem, novel antimalarial drugs are urgently needed, especially those that
Externí odkaz:
https://doaj.org/article/93b12d83f6f74bde8f392ab58d0b99ea
Autor:
Nicoleta Anghel, Vreni Balmer, Joachim Müller, Pablo Winzer, Adriana Aguado-Martinez, Mona Roozbehani, Sovitj Pou, Aaron Nilsen, Michael Riscoe, J. Stone Doggett, Andrew Hemphill
Publikováno v:
Frontiers in Veterinary Science, Vol 5 (2018)
We report on the efficacy of selected endochin-like quinolones (ELQs) against N. caninum tachyzoites grown in human foreskin fibroblasts (HFF), and in a pregnant BALB/c mouse model. Fourteen ELQs were screened against transgenic N. caninum tachyzoite
Externí odkaz:
https://doaj.org/article/e77756f34e184cd3b80487fcf8046c1a
Autor:
Anasuya C Pal, Isaline Renard, Pallavi Singh, Pratap Vydyam, Joy E Chiu, Sovitj Pou, Rolf W Winter, Rozalia Dodean, Lisa Frueh, Aaron C Nilsen, Michael K Riscoe, J Stone Doggett, Choukri Ben Mamoun
Publikováno v:
J Infect Dis
Human babesiosis is a malaria-like illness caused by tick-borne intraerythrocytic Babesia parasites of the Apicomplexa phylum. Whereas several species of Babesia can cause severe disease in humans, the ability to propagate Babesia duncani both in vit
Autor:
Katherine M. Liebman, Aaron Nilsen, Rolf W. Winter, Michael K. Riscoe, Lisa Frueh, David R. Stuart, Robert T. Jacobs, J. Stone Doggett, Rory T. Gallagher, Haihong Jin, Sovitj Pou, Rozalia Dodean
Publikováno v:
Organic Process Research & Development. 25:1841-1852
Autor:
Isaline Renard, Rolf W. Winter, Pallavi Singh, Michael K. Riscoe, Pratap Vydyam, Anasuya Chattopadhyay Pal, Sovitj Pou, Rozalia A. Dodean, A. C. Nilsen, J. S. Doggett, L. Frueh, Choukri Ben Mamoun, Joy E. Chiu
Hematozoa are a subclass of protozoan parasites that invade and develop within vertebrate red blood cells to cause the pathological symptoms associated with diseases of both medical and veterinary importance such as malaria and babesiosis. A major li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b0448c9f61c8713c9df3509ac4b8170
https://doi.org/10.1101/2021.12.01.470698
https://doi.org/10.1101/2021.12.01.470698
Autor:
Roland A. Cooper, Susan E. Leed, Qiang Zeng, Kevin A. Reynolds, Lacy Gaynor-Ohnstad, Lisa Xie, Hsiuling Lin, Jason C. Sousa, Jianbing Mu, Heather Gaona, Raul Olmeda, Martin J. Smilkstein, Brett R. Bayles, Brittney Potter, Michael K. Riscoe, Richard J. Sciotti, Papireddy Kancharla, Yuexin Li, Brian Vesely, Sovitj Pou, Sean R. Marcsisin, Chau Vuong, Qigui Li, Brandon S. Pybus, Lisa Read, Victor Melendez, Norma Roncal, Thu Lan Luong, Diana Caridha, Chad C. Black, Rozalia A. Dodean, Jing Zhang, Kirk Butler, Patrick K Tumwebaze, Charles E. Bane, Philip J. Rosenthal, Stephanie A Rasmussen, Mara Kreishman-Deitrick, Jane Xu Kelly, Frida G. Ceja, Ping Zhang, Christina K. Nolan
Publikováno v:
J Med Chem
The global impact of malaria remains staggering despite extensive efforts to eradicate the disease. With increasing drug resistance and the absence of a clinically available vaccine, there is an urgent need for novel, affordable, and safe drugs for p
Autor:
Pallavi Singh, Michael K. Riscoe, Aaron Nilsen, Choukri Ben Mamoun, Anasuya Chattopadhyay Pal, Isaline Renard, Shalev Gihaz, Pratap Vydyam, Rolf W. Winter, Madelyn Kumar, Sovitj Pou, Rozalia Dodean, Joy E. Chiu, Jose Thekkiniath, J. Stone Doggett, Lisa Frueh
Publikováno v:
Antimicrobial Agents and Chemotherapy. 65
An effective strategy to control blood-borne diseases and prevent outbreak recrudescence involves targeting conserved metabolic processes that are essential for pathogen viability. One such target for Plasmodium and Babesia, the infectious agents of
Autor:
Joy E, Chiu, Isaline, Renard, Anasuya C, Pal, Pallavi, Singh, Pratap, Vydyam, Jose, Thekkiniath, Madelyn, Kumar, Shalev, Gihaz, Sovitj, Pou, Rolf W, Winter, Rozalia, Dodean, Lisa, Frueh, Aaron C, Nilsen, Michael K, Riscoe, J Stone, Doggett, Choukri Ben, Mamoun
Publikováno v:
Antimicrob Agents Chemother
An effective strategy to control blood-borne diseases and prevent outbreak recrudescence involves targeting conserved metabolic processes that are essential for pathogen viability. One such target for Plasmodium and Babesia, the infectious agents of