Surface engineering of silica nanoparticles for oral insulin delivery: Characterization and cell toxicity studies

Autor: Andreani, Tatiana, Kiill, Charlene P., Souza, Ana Luiza R. de, Fangueiro, Joana F., Fernandes, Lisete, Doktorovová, Slavomira, Santos, Dario L., Garcia, Maria L., Gremião, Maria Palmira D., Souto, Eliana B., Silva, Amélia M.

Publikováno v: In Colloids and Surfaces B: Biointerfaces 1 November 2014 123:916-923

biochemistry physiological effects and the role of DDP-IV inhibitors in the management of type 2 diabetes mellitus

Autor: Andreani, Tatiana, Silva, Amélia M., Souza, Ana Luiza R. de

Type-2 diabetes mellitus (T2DM) is a metabolic disease characterized mainly by hyperglycemia, resulting from defects in β-cell function and/or insulin resistance. Treatment approaches include diet, exercise, and pharmacological agents these however

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1445::7c9bb371ed2605b9d5b51a3fc128b235
https://hdl.handle.net/10284/2973

The Influence of Polysaccharide Coating on the Physicochemical Parameters and Cytotoxicity of Silica Nanoparticles for Hydrophilic Biomolecules Delivery.

Autor: Andreani T; CITAB - Centre for Research and Technology of Agro-Environmental and Biological Sciences, University of Trás-os-Montes e Alto Douro, Quinta de Prados, 5001-801 Vila Real, Portugal. tatiana.andreani@fc.up.pt.; Department of Biology and Environment, University of Trás-os-Montes e Alto Douro, 5001-801 Vila Real, Portugal. tatiana.andreani@fc.up.pt.; CIQUP - Research Center in Chemistry, Department of Chemistry and Biochemistry, Faculty of Sciences, Porto University, Rua do Campo Alegre, s/n, 4169-007 Porto, Portugal. tatiana.andreani@fc.up.pt., Fangueiro JF; CITAB - Centre for Research and Technology of Agro-Environmental and Biological Sciences, University of Trás-os-Montes e Alto Douro, Quinta de Prados, 5001-801 Vila Real, Portugal., Severino P; Institute of Technology and Research, University of Tiradentes, Avenida Murilo Dantas, Farolândia, Aracaju, Brazil., Souza ALR; Faculty of Pharmaceutical Sciences, Universidade Estadual Paulista, UNESP, Rodovia Araraquara-Jau, Km. 01, Araraquara, São Paulo, Brazil., Martins-Gomes C; CITAB - Centre for Research and Technology of Agro-Environmental and Biological Sciences, University of Trás-os-Montes e Alto Douro, Quinta de Prados, 5001-801 Vila Real, Portugal.; Department of Biology and Environment, University of Trás-os-Montes e Alto Douro, 5001-801 Vila Real, Portugal., Fernandes PMV; CIQUP - Research Center in Chemistry, Department of Chemistry and Biochemistry, Faculty of Sciences, Porto University, Rua do Campo Alegre, s/n, 4169-007 Porto, Portugal., Calpena AC; Biopharmacy and Pharmacokinetic Unit, Pharmacy and Pharmaceutical Technology Department, School of Pharmacy, University of Barcelona, Av. Joan XXIII, s/n, 8028 Barcelona, Spain., Gremião MP; Faculty of Pharmaceutical Sciences, Universidade Estadual Paulista, UNESP, Rodovia Araraquara-Jau, Km. 01, Araraquara, São Paulo, Brazil., Souto EB; Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Coimbra (FFUC), Pólo das Ciências da Saúde, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal. ebsouto@ebsouto.pt.; CEB - Centre of Biological Engineering, University of Minho, Campus de Gualtar 4710-057 Braga, Portugal. ebsouto@ebsouto.pt., Silva AM; CITAB - Centre for Research and Technology of Agro-Environmental and Biological Sciences, University of Trás-os-Montes e Alto Douro, Quinta de Prados, 5001-801 Vila Real, Portugal. amsilva@utad.pt.; Department of Biology and Environment, University of Trás-os-Montes e Alto Douro, 5001-801 Vila Real, Portugal. amsilva@utad.pt.

Publikováno v: Nanomaterials (Basel, Switzerland) [Nanomaterials (Basel)] 2019 Jul 27; Vol. 9 (8). Date of Electronic Publication: 2019 Jul 27.