Zobrazeno 1 - 10
of 278
pro vyhledávání: '"Souvik Maiti"'
Autor:
Sundaram Acharya, Asgar Hussain Ansari, Prosad Kumar Das, Seiichi Hirano, Meghali Aich, Riya Rauthan, Sudipta Mahato, Savitri Maddileti, Sajal Sarkar, Manoj Kumar, Rhythm Phutela, Sneha Gulati, Abdul Rahman, Arushi Goel, C. Afzal, Deepanjan Paul, Trupti Agrawal, Vinay Kumar Pulimamidi, Subhadra Jalali, Hiroshi Nishimasu, Indumathi Mariappan, Osamu Nureki, Souvik Maiti, Debojyoti Chakraborty
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract The clinical success of CRISPR therapies hinges on the safety and efficacy of Cas proteins. The Cas9 from Francisella novicida (FnCas9) is highly precise, with a negligible affinity for mismatched substrates, but its low cellular targeting e
Externí odkaz:
https://doaj.org/article/967b3513bca24917a4d3b9306cf6ba0f
Autor:
Meghali Aich, Asgar Hussain Ansari, Li Ding, Vytautas Iesmantavicius, Deepanjan Paul, Chunaram Choudhary, Souvik Maiti, Frank Buchholz, Debojyoti Chakraborty
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113177- (2023)
Summary: Embryonic stem cells (ESCs) can undergo lineage-specific differentiation, giving rise to different cell types that constitute an organism. Although roles of transcription factors and chromatin modifiers in these cells have been described, ho
Externí odkaz:
https://doaj.org/article/e474f254575642cfab7f110e3f4cb827
Autor:
Souvik Maiti, Stephen E. Congly, Christopher Ma, Karen Olympia-Sy, Lorian Hardcastle, Melanie P. Stapleton, Nauzer Forbes
Publikováno v:
Gastro Hep Advances, Vol 2, Iss 2, Pp 163-169 (2023)
Background and Aims: Endoscopic procedures are frequently performed in Canada but can be associated with potential complications and medicolegal implications. This study aimed to identify potential medicolegal cases in Canada relating to upper and lo
Externí odkaz:
https://doaj.org/article/88d80878a1e54a98b13f156a575fa659
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 30, Iss , Pp 241-256 (2022)
The triple-helix structure at the 3′ end of metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), a long non-coding RNA, has been considered to be a target for modulating the oncogenic functions of MALAT1. This study examines the binding
Externí odkaz:
https://doaj.org/article/fe1f09b2321645b9af2489e0533c2795
Autor:
Shuvra Shekhar Roy, Shalu Sharma, Zaigham Abbas Rizvi, Dipanjali Sinha, Divya Gupta, Mercy Rophina, Paras Sehgal, Srikanth Sadhu, Manas Ranjan Tripathy, Sweety Samal, Souvik Maiti, Vinod Scaria, Sridhar Sivasubbu, Amit Awasthi, Krishnan H. Harshan, Sanjeev Jain, Shantanu Chowdhury
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
The COVID-19 pandemic caused by SARS-CoV-2 has caused millions of infections and deaths worldwide. Limited treatment options and the threat from emerging variants underline the need for novel and widely accessible therapeutics. G-quadruplexes (G4s) a
Externí odkaz:
https://doaj.org/article/be185dc57a37426ca40b3079c5373adf
Publikováno v:
eLife, Vol 12 (2023)
CRISPR-based diagnostics (CRISPRDx) have improved clinical decision-making, especially during the COVID-19 pandemic, by detecting nucleic acids and identifying variants. This has been accelerated by the discovery of new and engineered CRISPR effector
Externí odkaz:
https://doaj.org/article/e9058db168224535aaecc8ed90854304
Autor:
Arpita Ghosh, Nihar Ranjan, Liuwei Jiang, Asgar Hussain Ansari, Natalya Degyatoreva, Shivaksh Ahluwalia, Dev P. Arya, Souvik Maiti
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 685-698 (2022)
MicroRNAs (miRs) are a class of endogenously expressed non-coding RNAs that negatively regulate gene expression within cells and participate in maintaining cellular homeostasis. By targeting 3′ UTRs of target genes, individual miRs can control a wi
Externí odkaz:
https://doaj.org/article/f11477af4978492e919373d5809ad08a
Autor:
Manoj Kumar, Sneha Gulati, Asgar H Ansari, Rhythm Phutela, Sundaram Acharya, Mohd Azhar, Jayaram Murthy, Poorti Kathpalia, Akshay Kanakan, Ranjeet Maurya, Janani Srinivasa Vasudevan, Aparna S, Rajesh Pandey, Souvik Maiti, Debojyoti Chakraborty
Publikováno v:
eLife, Vol 10 (2021)
The COVID-19 pandemic originating in the Wuhan province of China in late 2019 has impacted global health, causing increased mortality among elderly patients and individuals with comorbid conditions. During the passage of the virus through affected po
Externí odkaz:
https://doaj.org/article/f5788d259c3a4647be05cf2a2bbe03f3
Autor:
Biplab Roy, Pritam Guha, Prasant Nahak, Gourab Karmakar, Souvik Maiti, Amit Kumar Mandal, Alexey G. Bykov, Alexander V. Akentiev, Boris A. Noskov, Koji Tsuchiya, Kanjiro Torigoe, Amiya Kumar Panda
Publikováno v:
ACS Omega, Vol 3, Iss 9, Pp 12235-12245 (2018)
Externí odkaz:
https://doaj.org/article/60051b2134ea44ff9fb5129da3c73144
Autor:
Kriti Kaushik, Ambily Sivadas, Shamsudheen Karuthedath Vellarikkal, Ankit Verma, Rijith Jayarajan, Satyaprakash Pandey, Tavprithesh Sethi, Souvik Maiti, Vinod Scaria, Sridhar Sivasubbu
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-17 (2018)
Abstract Background RNA is known to play diverse roles in gene regulation. The clues for this regulatory function of RNA are embedded in its ability to fold into intricate secondary and tertiary structure. Results We report the transcriptome-wide RNA
Externí odkaz:
https://doaj.org/article/2f5c9401655340998cf64401e0d48df4