Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Souvik Chattopadhaya"'
Autor:
Bo-Hwa Choi, Souvik Chattopadhaya, Le Nguyen Thanh, Lin Feng, Quoc Toan Nguyen, Chuan Bian Lim, Amaravadhi Harikishore, Ravi Prakash Reddy Nanga, Nagakumar Bharatham, Yan Zhao, Xuewei Liu, Ho Sup Yoon
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0201149 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0110955.].
Externí odkaz:
https://doaj.org/article/9a8443cb237e45ac90a279079a92555f
Autor:
Bo-Hwa Choi, Souvik Chattopadhaya, Le Nguyen Thanh, Lin Feng, Quoc Toan Nguyen, Chuan Bian Lim, Amaravadhi Harikishore, Ravi Prakash Reddy Nanga, Nagakumar Bharatham, Yan Zhao, Xuewei Liu, Ho Sup Yoon
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110955 (2014)
Microtubules are a highly validated target in cancer therapy. However, the clinical development of tubulin binding agents (TBA) has been hampered by toxicity and chemoresistance issues and has necessitated the search for new TBAs. Here, we report the
Externí odkaz:
https://doaj.org/article/fb9ae4696cbc49f085e1ae040ab6e2e1
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9789811387180
Deregulation of protein kinase activity has been linked to many diseases ranging from cancer to AIDS and neurodegenerative diseases. Not surprisingly, drugging the human kinome - the complete set of kinases encoded by the human genome - has been one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4028568535fc2cb1f7fe50c7a6dc035f
https://doi.org/10.1007/978-981-13-8719-7_11
https://doi.org/10.1007/978-981-13-8719-7_11
Autor:
Lin Feng, Nagakumar Bharatham, Amaravadhi Harikishore, Le Nguyen Thanh, Xue-Wei Liu, Souvik Chattopadhaya, Quoc Toan Nguyen, Yan Zhao, Chuan Bian Lim, Ho Sup Yoon, Bo-Hwa Choi, Ravi Prakash Reddy Nanga
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0201149 (2018)
PLoS ONE
PLoS ONE
Microtubules are a highly validated target in cancer therapy. However, the clinical development of tubulin binding agents (TBA) has been hampered by toxicity and chemoresistance issues and has necessitated the search for new TBAs. Here, we report the
Autor:
Ding Shumin, Xiaoqian Liu, Lin Qiu, Li Liu, Jianhao Wang, Liqian Gao, Peng Miao, Jiang Xia, Pengju Jiang, Souvik Chattopadhaya, Jianpeng Wang, Fan Jie
Publikováno v:
Electrophoresis. 38(19)
Herein, a novel assay has been developed for monitoring PreScission protease (His-PSP) mediated enzyme cleavage of ATTO 590 labeled peptide substrate (ATTO-LEV). This novel method is based on combining the use of capillary electrophoresis and fluores
Publikováno v:
Analytical and Bioanalytical Chemistry. 386:416-426
Recent advances in proteomics have provided impetus towards the development of robust technologies for high-throughput studies of enzymes. The term "catalomics" defines an emerging '-omics' field in which high-throughput studies of enzymes are carrie
Publikováno v:
Tetrahedron Letters. 46:4053-4056
We have developed an affinity-based probe for the proteomic profiling of aspartic proteases. Our probe was shown to be selective towards aspartic proteases over other proteins. It was also shown that the strategy may be used to label selectively aspa
Publikováno v:
Scopus-Elsevier
TNF-α transduces signals of survival or death via its two receptors, R1/p55/p60 and RII/p80/p75. The role of caspases as effectors of cell death is universally accepted, although caspase inhibitors may potentiate TNF cytotoxicity in some instances.
Publikováno v:
Mechanisms in Parkinson's Disease-Models and Treatments
Parkinson’s disease (PD) is the second most common neurodegenerative disease among the elderly. While sporadic PD constitutes 99% of the cases, the remaining 1% is of genetic origin. The neuropathological hallmarks of PD are progressive degeneratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f267c5b3a393879cddfaf5155cfac99
http://www.intechopen.com/articles/show/title/role-of-fkbps-in-parkinson-s-disease
http://www.intechopen.com/articles/show/title/role-of-fkbps-in-parkinson-s-disease
Publikováno v:
ResearcherID
Protein misfolding has been implicated in the pathophysiology of several neurodegenerative 'amyloidoses' that includes Alzheimer's, Parkinson's, Huntington's disease, frontotemporal dementia and amyotrophic lateral sclerosis. Accumulation of misfolde