Zobrazeno 1 - 10
of 308
pro vyhledávání: '"Sourav Saha"'
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114522- (2024)
Summary: Persistent DNA-protein crosslinks formed by human topoisomerase IIIα (TOP3A-DPCs) interfere with DNA metabolism and lead to genome damage and cell death. Recently, we demonstrated that such abortive TOP3A-DPCs are ubiquitylated and proteoly
Externí odkaz:
https://doaj.org/article/d74253d5611f45648bc092a2b6052b6d
Publikováno v:
Clinical Case Reports, Vol 12, Iss 4, Pp n/a-n/a (2024)
Key Clinical Message We present a rare case of primary antiphospholipid syndrome in a 38‐year‐old male who presented with painful digital ischemia. Early initiation of anticoagulation and addition of glucocorticoid led to a significant improvemen
Externí odkaz:
https://doaj.org/article/d74cee02185b41aaaf33c4aafb6a1418
Autor:
Sourav Saha, Shar-yin Naomi Huang, Xi Yang, Liton Kumar Saha, Yilun Sun, Prashant Khandagale, Lisa M. Jenkins, Yves Pommier
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract TOP3B is stabilized by TDRD3. Hypothesizing that TDRD3 recruits a deubiquitinase, we find that TOP3B interacts with USP9X via TDRD3. Inactivation of USP9X destabilizes TOP3B, and depletion of both TDRD3 and USP9X does not promote further TOP
Externí odkaz:
https://doaj.org/article/32a167d0443e46a897d892cea4d72fd8
Publikováno v:
IDCases, Vol 36, Iss , Pp e01944- (2024)
Nalidixic acid-resistant Salmonella enterica serotype Typhi is a well-known cause of enteric fever, and its prevalence is increasing worldwide. However, the incidence of enteric fever complicated by non-immune hemolytic anemia without co-existing tha
Externí odkaz:
https://doaj.org/article/26f8571565b5462c88e12005f9a42a0c
Publikováno v:
Data in Brief, Vol 51, Iss , Pp 109568- (2023)
In the domain of vision-based applications, the importance of text cannot be underestimated due to its natural capacity to provide accurate and comprehensive information. The application of scene text editing systems enables the modification and enha
Externí odkaz:
https://doaj.org/article/58800848e3014346b8e30c11dcd80b07
Autor:
Liton Kumar Saha, Sourav Saha, Xi Yang, Shar-yin Naomi Huang, Yilun Sun, Ukhyun Jo, Yves Pommier
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
This study provides evidence that human topoisomerase IIIα (TOP3A) is closely associated with active replisomes. The authors uncover TOP3A DNA cleavage complexes (TOP3Accs) repair mechanisms to ensure normal DNA replication and genome integrity.
Externí odkaz:
https://doaj.org/article/9d63d9cf54ec4c5eb9ecd3f0d8455716
Publikováno v:
IEEE Access, Vol 11, Pp 130206-130229 (2023)
The Industrial Internet of Things (IIoT) is able to connect machines, analytics and people with IoT smart devices, gateway nodes and edge devices to create powerful intuitivenesses to drive smarter, faster and effective business agreements. IIoT havi
Externí odkaz:
https://doaj.org/article/766cf73ee1394555a47f8156b94527a8
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
The authors revealed novel roles of catalytic residues and divalent metal ions for hsTOP3B, the human RNA topoisomerase, and demonstrated the structural elements that kinetically modulate the DNA and RNA topoisomerase activities of TOP3B.
Externí odkaz:
https://doaj.org/article/a62f3f182d8847f38bd06bce5d1e33e8
Publikováno v:
Results in Engineering, Vol 17, Iss , Pp 100862- (2023)
Mixed convection in an open cavity has been growing into one of the most attractive topics of investigation for years, owing to its importance in many engineering applications. In this study, the effect of different inflow conditions on mixed conve
Externí odkaz:
https://doaj.org/article/1b614da43e084965bf41181e77c5ca5e
Autor:
Sandeep R. Kaushik, Sukanya Sahu, Hritusree Guha, Sourav Saha, Ranjit Das, Rukuwe-u Kupa, Wetetsho Kapfo, Trinayan Deka, Rumi Basumatary, Asunu Thong, Arunabha Dasgupta, Bidhan Goswami, Amit Kumar Pandey, Lahari Saikia, Vinotsole Khamo, Anjan Das, Ranjan Kumar Nanda
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Tuberculosis (TB) patients show dysregulated immunity, iron metabolism, and anemia. In this study, circulatory cytokines, trace metals, and iron-related proteins (hepcidin, ferroportin, transferrin, Dmt1, Nramp1, ferritin, ceruloplasmin, hemojuvelin,
Externí odkaz:
https://doaj.org/article/9ed2da43056543ba8ddde6aa7a269105