Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sourav Roy Choudhury"'
Autor:
Elsa Vazquez Arreola, Dean V. Coonrod, Sourav Roy Choudhury, William C. Knowler, Mary Hoskin, Dorota Wasak, Rachel Williams, Robert L. Hanson, Elena Pack, Rachel Caballero, Amanda Gonzalez, Madhumita Sinha
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background The prevalence of childhood obesity and diabetes continues to rise in the United States (US), especially among minority populations. The objective of the Early Tracking of Childhood Health Determinants (ETCHED) study is to investi
Externí odkaz:
https://doaj.org/article/86f921361b2e446089672b9782e749ed
Autor:
Sourav Roy Choudhury, Ellen Sapp, Lorelei Stoica, Damien J. Cabral, Jacob A. Johnson, Heather L. Gray-Edwards, Marian DiFiglia, Qin Su, Miguel Sena-Esteves, Douglas R. Martin, Anne F Harris, Allison M. Keeler, Neil Aronin, Guangping Gao, Aime K. Johnson, Jennifer S Ferreira
Publikováno v:
Molecular Therapy. 24(4):726-735
Effective gene delivery to the central nervous system (CNS) is vital for development of novel gene therapies for neurological diseases. Adeno-associated virus (AAV) vectors have emerged as an effective platform for in vivo gene transfer, but overall
Autor:
Xandra O. Breakefield, Paola Grandi, Eloise Hudry, Sourav Roy Choudhury, Casey A. Maguire, Miguel Sena-Esteves
Neurological disorders - disorders of the brain, spine and associated nerves - are a leading contributor to global disease burden with a shockingly large associated economic cost. Various treatment approaches - pharmaceutical medication, device-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d33d26bf054423bc4ee636f8384c903
https://europepmc.org/articles/PMC5929167/
https://europepmc.org/articles/PMC5929167/
Autor:
Kathryn R. Wagner, Aime K. Johnson, Jacob A. Johnson, Rohit Sharma, Zachary Fitzpatrick, Claudio Punzo, Shan Ma, Anne F Harris, Robert M. Kotin, Yuanfan Zhang, Heather L. Gray-Edwards, Laura C. Alonso, Miguel Sena-Esteves, Stacy Maitland, Casey A. Maguire, Sourav Roy Choudhury, Jennifer S Ferreira, Douglas R. Martin
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 24(7)
Adeno-associated viral (AAV) vectors have shown promise as a platform for gene therapy of neurological disorders. Achieving global gene delivery to the central nervous system (CNS) is key for development of effective therapies for many of these disea
Autor:
Christian Mueller, Evren Kocabas, Kathryn R. Wagner, Florie Borel, Sourav Roy Choudhury, Terence R. Flotte, Huaming Sun, Lina Song, Arun Srivastava, George Aslanidi, Miguel Sena Esteves, Qiushi Tang
Publikováno v:
Molecular Therapy. 23:S73
Alpha-one antitrypsin deficiency (AATD) is a genetic disorder that causes defective production of alpha-one antitrypsin (AAT), leading to decreased AAT activity in the blood and lungs, and deposition of excessive mutant Z-AAT protein in liver cells.
Autor:
Sourav Roy Choudhury, Lorelei Stoica, Aime K. Johnson, Heather L. Gray-Edwards, Jacob A. Johnson, Douglas R. Martin, Miguel Sena-Esteves, Anne F Harris, Damien J. Cabral
Publikováno v:
Molecular Therapy. 23:S105
Effective gene transfer to CNS is key for development of new therapies for neurological diseases. Relatively few natural AAV capsids cross the blood-brain barrier (BBB) upon systemic infusion and even then, transduction in adult brain after systemic