Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Sourabh Chand"'
Autor:
Katherine Angela Benson, Sourabh Chand, Alexander Peter Maxwell, Laura Jane Smyth, Jill Kilner, Richard Borrows, Amy Jayne McKnight
Publikováno v:
BMC Research Notes, Vol 10, Iss 1, Pp 1-15 (2017)
Abstract Background Biologically active vitamin D has an important regulatory role within the genome. It binds the vitamin D receptor (VDR) in order to control the expression of a wide range of genes as well as interacting with the epigenome to modif
Externí odkaz:
https://doaj.org/article/7719752983a34bb1a9785c1f804e5237
Autor:
Sourabh Chand, David Atkinson, Clare Collins, David Briggs, Simon Ball, Adnan Sharif, Kassiani Skordilis, Bindu Vydianath, Desley Neil, Richard Borrows
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162278 (2016)
BACKGROUND:Causes of "true" late kidney allograft failure remain unclear as study selection bias and limited follow-up risk incomplete representation of the spectrum. METHODS:We evaluated all unselected graft failures from 2008-2014 (n = 171; 0-36 ye
Externí odkaz:
https://doaj.org/article/246ed5c2f13b48e2a3876c34a593fad9
Autor:
Sourabh Chand, Colin D Chue, Nicola C Edwards, James Hodson, Matthew J Simmonds, Alexander Hamilton, Stephen C L Gough, Lorraine Harper, Rick P Steeds, Jonathan N Townend, Charles J Ferro, Richard Borrows
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0116160 (2015)
Chronic kidney disease (CKD) is associated with accelerated cardiovascular disease and heart failure. Endothelial nitric oxide synthase (eNOS) Glu298Asp single nucleotide polymorphism (SNP) genotype has been associated with a worse phenotype amongst
Externí odkaz:
https://doaj.org/article/052e4a3a688f4ac1b8427321f84b839d
Autor:
Sourabh Chand, Julia U Holle, Marc Hilhorst, Matthew J Simmonds, Stuart Smith, Lavanya Kamesh, Peter Hewins, Amy Jayne McKnight, Alexander P Maxwell, Jan Willem Cohen Tervaert, Stefan Wieczorek, Lorraine Harper, Richard Borrows
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69022 (2013)
Immunosuppression is cornerstone treatment of antineutrophil cytoplasmic antibody associated vasculitis (AAV) but is later complicated by infection, cancer, cardiovascular and chronic kidney disease. Caveolin-1 is an essential structural protein for
Externí odkaz:
https://doaj.org/article/22ec0a87d3b5496085a6b00e830a4d44
Autor:
Lorraine Harper, Alexander P. Maxwell, Winnie Chan, Sourabh Chand, Shazia Shabir, Amy Jayne McKnight, Jennifer A. McCaughan, Richard Borrows
Publikováno v:
BBA Clinical
Introduction Despite excellent first year outcomes in kidney transplantation, there remain significant long-term complications related to new-onset diabetes after transplantation (NODAT). The purpose of this study was to validate the findings of prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fa0412469db53dd60d4c9ad4fe6da23
https://doi.org/10.1016/j.bbacli.2015.12.004
https://doi.org/10.1016/j.bbacli.2015.12.004
Autor:
Simon Ball, S. Kuravi, Richard Borrows, Helen Smith, Lorraine Harper, Paul Moss, Baksho Kaul, Shazia Shabir, Sourabh Chand, S. Jham, Annette Pachnio
Publikováno v:
American Journal of Transplantation. 16:1113-1128
Emerging data suggest that expansion of a circulating population of atypical, cytotoxic CD4(+) T cells lacking costimulatory CD28 (CD4(+) CD28(null) cells) is associated with latent cytomegalovirus (CMV) infection. The purpose of the current study wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b69af272d974217ec857b66cc57cf5f
https://doi.org/10.1111/ajt.13614
https://doi.org/10.1111/ajt.13614
Autor:
Sourabh Chand
Caveolin-1 is the essential structural formation for lipid raft formation. It has been ascribed to several disease processes in humans due to its ubiquitous distribution. Patients with chronic kidney disease suffer great morbidity and mortality where
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ace84b2cccb3dfde96c4ffddfad7086
https://zenodo.org/record/2545409
https://zenodo.org/record/2545409
Autor:
Sourabh Chand
This short review describes the strategies employed for investigating genetic variation in chronic kidney disease as well as highlighting potential shortfalls that should be overcome in future studies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f8f675db01b27dc93bc88ebd8583afd
https://zenodo.org/record/2545415
https://zenodo.org/record/2545415