Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Sourabh, Dhingra"'
Autor:
Matthew R. James, Mariano A. Aufiero, Elisa M. Vesely, Sourabh Dhingra, Ko-Wei Liu, Tobias M. Hohl, Robert A. Cramer
Publikováno v:
mSphere, Vol 8, Iss 6 (2023)
ABSTRACTInvasive pulmonary aspergillosis (IPA) is a life-threatening infection caused by species in the ubiquitous fungal genus Aspergillus. While leukocyte-generated reactive oxygen species (ROS) are critical for the clearance of fungal conidia from
Externí odkaz:
https://doaj.org/article/b1a8c90b1e614aafa9fc55a36ec2fa4d
Autor:
Apoorva Dabholkar, Sandesh Pandit, Ritu Devkota, Sourabh Dhingra, Sophie Lorber, Olivier Puel, Ana M. Calvo
Publikováno v:
Journal of Fungi, Vol 10, Iss 2, p 103 (2024)
Aspergillus fumigatus is the leading cause of aspergillosis, associated with high mortality rates, particularly in immunocompromised individuals. In search of novel genetic targets against aspergillosis, we studied the WOPR transcription factor OsaA.
Externí odkaz:
https://doaj.org/article/956b468c2e9e4a07afaa22d5fdcb2ee4
Autor:
Sandesh S Pandit, Jinfang Zheng, Yanbin Yin, Sophie Lorber, Olivier Puel, Sourabh Dhingra, Eduardo A Espeso, Ana M Calvo
Publikováno v:
PLoS ONE, Vol 18, Iss 7, p e0286271 (2023)
In fungi, conserved homeobox-domain proteins are transcriptional regulators governing development. In Aspergillus species, several homeobox-domain transcription factor genes have been identified, among them, hbxA/hbx1. For instance, in the opportunis
Externí odkaz:
https://doaj.org/article/313dca6f2a5e4604b608ebf51a1e1f20
Autor:
Sourabh Dhingra, Caitlin H. Kowalski, Arsa Thammahong, Sarah R. Beattie, Katherine M. Bultman, Robert A. Cramer
Publikováno v:
mSphere, Vol 4, Iss 5 (2019)
Externí odkaz:
https://doaj.org/article/626294970999487ca95cf87fa733e72b
Publikováno v:
mSphere, Vol 4, Iss 3 (2019)
ABSTRACT Regulation of fungal cell wall biosynthesis is critical to maintain cell wall integrity in dynamic fungal infection microenvironments. Genes involved in this response that impact fungal fitness and host immune responses remain to be fully de
Externí odkaz:
https://doaj.org/article/74dcdc5f93b44ab982463475e32f51af
Publikováno v:
mBio, Vol 8, Iss 2 (2017)
ABSTRACT Trehalose biosynthesis is found in fungi but not humans. Proteins involved in trehalose biosynthesis are essential for fungal pathogen virulence in humans and plants through multiple mechanisms. Loss of canonical trehalose biosynthesis genes
Externí odkaz:
https://doaj.org/article/722d315d73094eda87a9ec6bd827d0fd
Autor:
Sarah R Beattie, Kenneth M K Mark, Arsa Thammahong, Laure Nicolas Annick Ries, Sourabh Dhingra, Alayna K Caffrey-Carr, Chao Cheng, Candice C Black, Paul Bowyer, Michael J Bromley, Joshua J Obar, Gustavo H Goldman, Robert A Cramer
Publikováno v:
PLoS Pathogens, Vol 13, Iss 4, p e1006340 (2017)
Aspergillus fumigatus is responsible for a disproportionate number of invasive mycosis cases relative to other common filamentous fungi. While many fungal factors critical for infection establishment are known, genes essential for disease persistence
Externí odkaz:
https://doaj.org/article/40beb8360aa749b996a4d96db9aef212
Autor:
Sourabh Dhingra, Caitlin H. Kowalski, Arsa Thammahong, Sarah R. Beattie, Katherine M. Bultman, Robert A. Cramer
Publikováno v:
mSphere, Vol 1, Iss 2 (2016)
ABSTRACT SREBP transcription factors play a critical role in fungal virulence; however, the mechanisms of sterol regulatory element binding protein (SREBP) activation in pathogenic fungi remains ill-defined. Screening of the Neurospora crassa whole-g
Externí odkaz:
https://doaj.org/article/2dbc1336bcb4432ea6583a561c837fb1
Autor:
Alayna K. Caffrey-Carr, Vanessa Espinosa, Amariliz Rivera, Joshua J. Obar, Robert A. Cramer, Walburga Croteau, Sourabh Dhingra, Ko-Wei Liu, Xi Wang
Publikováno v:
The Journal of Immunology. 205:3058-3070
RIG-I–like receptors (RLR) are cytosolic RNA sensors that signal through the MAVS adaptor to activate IFN responses against viruses. Whether the RLR family has broader effects on host immunity against other pathogen families remains to be fully exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2884419b41d20b0622345315529a8853
https://doi.org/10.4049/jimmunol.2000802
https://doi.org/10.4049/jimmunol.2000802
Autor:
Sourabh Dhingra
Publikováno v:
Current Clinical Microbiology Reports. 7:133-141
Purpose of Review Non-coding RNAs (ncRNAs), including regulatory small RNAs (sRNAs) and long non-coding RNAs (lncRNAs), constitute a significant part of eukaryotic genomes; however, their roles in fungi are just starting to emerge. ncRNAs have been s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::478b45c3e6c9a559a8e4a2cf08bb8947
https://doi.org/10.1007/s40588-020-00151-7
https://doi.org/10.1007/s40588-020-00151-7