Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Souquette A"'
Autor:
Marlies Boeren, Nicky de Vrij, My K. Ha, Sebastiaan Valkiers, Aisha Souquette, Sofie Gielis, Mariia Kuznetsova, Jolien Schippers, Esther Bartholomeus, Johan Van den Bergh, Nele Michels, Olivier Aerts, Julie Leysen, An Bervoets, Julien Lambert, Elke Leuridan, Johan Wens, Karin Peeters, Marie-Paule Emonds, George Elias, Niels Vandamme, Hilde Jansens, Wim Adriaensen, Arvid Suls, Stijn Vanhee, Niel Hens, Evelien Smits, Pierre Van Damme, Paul G. Thomas, Philippe Beutels, Peter Ponsaerts, Viggo Van Tendeloo, Peter Delputte, Kris Laukens, Pieter Meysman, Benson Ogunjimi
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114062- (2024)
Summary: The role of T cell receptor (TCR) diversity in infectious disease susceptibility is not well understood. We use a systems immunology approach on three cohorts of herpes zoster (HZ) patients and controls to investigate whether TCR diversity a
Externí odkaz:
https://doaj.org/article/0b4efad8a12a42feb58eab2d4fa7e411
Autor:
Ericka Kirkpatrick Roubidoux, Pamela H. Brigleb, Kasi Vegesana, Aisha Souquette, Kendall Whitt, Pamela Freiden, St. Jude Investigative Team, Amanda Green, Paul G. Thomas, Maureen A. McGargill, Joshua Wolf, Stacey Schultz-Cherry
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract SARS-CoV-2 has caused millions of infections worldwide since its emergence in 2019. Understanding how infection and vaccination induce mucosal immune responses and how they fluctuate over time is important, especially since they are key in p
Externí odkaz:
https://doaj.org/article/cd3f41f8a7ef4395876cded0e4d9323d
Autor:
Boeren, Marlies, de Vrij, Nicky, Ha, My K., Valkiers, Sebastiaan, Souquette, Aisha, Gielis, Sofie, Kuznetsova, Maria, Schippers, Jolien, Bartholomeus, Esther, Van den Bergh, Johan, Michels, Nele, Aerts, Olivier, Leysen, Julie, Bervoets, An, Lambert, Julien, Leuridan, Elke, Wens, Johan, Peeters, Karin, Emonds, Marie-Paule, Elias, George, Vandamme, Niels, Jansens, Hilde, Adriaensen, Wim, Suls, Arvid, Vanhee, Stijn, Hens, Niel, Smits, Evelien, Van Damme, Pierre, Thomas, Paul G., Beutels, Philippe, Ponsaerts, Peter, Van Tendeloo, Viggo, Delputte, Peter, Laukens, Kris, Meysman, Pieter, Ogunjimi, Benson
Publikováno v:
In Cell Reports 23 April 2024 43(4)
Autor:
Aisha Souquette, Paul G Thomas
Publikováno v:
eLife, Vol 13 (2024)
Analysis of pre-existing immunity and its effects on acute infection often focus on memory responses associated with a prior infectious exposure. However, memory responses occur in the context of the overall immune state and leukocytes must interact
Externí odkaz:
https://doaj.org/article/7790eb86b4784bbcb2b00cb4722557ff
Autor:
Mark A. Brimble, Pei-Hsin Cheng, Stephen M. Winston, Isaiah L. Reeves, Aisha Souquette, Yunyu Spence, Junfang Zhou, Yong-Dong Wang, Christopher L. Morton, Marcus Valentine, Paul G. Thomas, Amit C. Nathwani, John T. Gray, Andrew M. Davidoff
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 24, Iss , Pp 280-291 (2022)
Recombinant adeno-associated virus (rAAV) vectors are increasingly being used for clinical gene transfer and have shown great potential for the treatment of several monogenic disorders. However, contaminant DNA from producer plasmids can be packaged
Externí odkaz:
https://doaj.org/article/9ce90bd19a374a6086d2a19259d8a399
Akademický článek
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Autor:
Magdalena L Russell, Aisha Souquette, David M Levine, Stefan A Schattgen, E Kaitlynn Allen, Guillermina Kuan, Noah Simon, Angel Balmaseda, Aubree Gordon, Paul G Thomas, Frederick A Matsen IV, Philip Bradley
Publikováno v:
eLife, Vol 11 (2022)
Every T cell receptor (TCR) repertoire is shaped by a complex probabilistic tangle of genetically determined biases and immune exposures. T cells combine a random V(D)J recombination process with a selection process to generate highly diverse and fun
Externí odkaz:
https://doaj.org/article/95bf64a4fda74d50b1793c5c3f136e61
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Autor:
George Elias, Pieter Meysman, Esther Bartholomeus, Nicolas De Neuter, Nina Keersmaekers, Arvid Suls, Hilde Jansens, Aisha Souquette, Hans De Reu, Marie-Paule Emonds, Evelien Smits, Eva Lion, Paul G Thomas, Geert Mortier, Pierre Van Damme, Philippe Beutels, Kris Laukens, Viggo Van Tendeloo, Benson Ogunjimi
Publikováno v:
eLife, Vol 11 (2022)
Antigen recognition through the T cell receptor (TCR) αβ heterodimer is one of the primary determinants of the adaptive immune response. Vaccines activate naïve T cells with high specificity to expand and differentiate into memory T cells. However
Externí odkaz:
https://doaj.org/article/ef8d3322e4b24849bf9e4eef3c1cad40
Autor:
Koshlan Mayer-Blackwell, Stefan Schattgen, Liel Cohen-Lavi, Jeremy C Crawford, Aisha Souquette, Jessica A Gaevert, Tomer Hertz, Paul G Thomas, Philip Bradley, Andrew Fiore-Gartland
Publikováno v:
eLife, Vol 10 (2021)
T-cell receptors (TCRs) encode clinically valuable information that reflects prior antigen exposure and potential future response. However, despite advances in deep repertoire sequencing, enormous TCR diversity complicates the use of TCR clonotypes a
Externí odkaz:
https://doaj.org/article/d1ecb3c26e0145ee974f654e715a1b6d