Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Soumya Sasi"'
Autor:
Michael L. Freeman, Girish Rachakonda, Kenneth J. Salleng, Joseph L. Roti Roti, Robert P. Van Der Waal, Soumya Sasi, Ling Geng, William Hayes McDonald, Amudhan Venkateswaran, Peter A. Crooks, Penthala Narsimha Reddy, Yerramreddy Thirupathi Reddy, Konjeti R. Sekhar
PDF file - 46KB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9a62dc0fe6866209154512b1cff19b0
https://doi.org/10.1158/1078-0432.22443465.v1
https://doi.org/10.1158/1078-0432.22443465.v1
Autor:
Michael L. Freeman, Girish Rachakonda, Kenneth J. Salleng, Joseph L. Roti Roti, Robert P. Van Der Waal, Soumya Sasi, Ling Geng, William Hayes McDonald, Amudhan Venkateswaran, Peter A. Crooks, Penthala Narsimha Reddy, Yerramreddy Thirupathi Reddy, Konjeti R. Sekhar
Purpose: Radiation therapy continues to be an important therapeutic strategy for providing definitive local/regional control of human cancer. However, oncogenes that harbor driver mutations and/or amplifications can compromise therapeutic efficacy. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c78317a8d510e86afb23b4a699634157
https://doi.org/10.1158/1078-0432.c.6519822
https://doi.org/10.1158/1078-0432.c.6519822
Autor:
Michael L. Freeman, Girish Rachakonda, Kenneth J. Salleng, Joseph L. Roti Roti, Robert P. Van Der Waal, Soumya Sasi, Ling Geng, William Hayes McDonald, Amudhan Venkateswaran, Peter A. Crooks, Penthala Narsimha Reddy, Yerramreddy Thirupathi Reddy, Konjeti R. Sekhar
PDF file - 173KB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::054edf54d46914b427298878650ca53d
https://doi.org/10.1158/1078-0432.22443462.v1
https://doi.org/10.1158/1078-0432.22443462.v1
Autor:
Michael L. Freeman, Joseph L. Roti Roti, James R. Lepock, Peter A. Crooks, Michael J. Borrelli, Robert G. Bristow, Ryuji Higashikubo, Nobuo Horikoshi, Jamil Sawani, Andrei Laszlo, Soumya Sasi, Venkatraj Muthusamy, Vijayakumar N. Sonar, Konjeti R. Sekhar
Supplementary Methods from Novel Chemical Enhancers of Heat Shock Increase Thermal Radiosensitization through a Mitotic Catastrophe Pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b11e3998223fa839248d54cc1751341
https://doi.org/10.1158/0008-5472.22366368
https://doi.org/10.1158/0008-5472.22366368
Autor:
Michael L. Freeman, Joseph L. Roti Roti, James R. Lepock, Peter A. Crooks, Michael J. Borrelli, Robert G. Bristow, Ryuji Higashikubo, Nobuo Horikoshi, Jamil Sawani, Andrei Laszlo, Soumya Sasi, Venkatraj Muthusamy, Vijayakumar N. Sonar, Konjeti R. Sekhar
Supplementary Figures 1-9 from Novel Chemical Enhancers of Heat Shock Increase Thermal Radiosensitization through a Mitotic Catastrophe Pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef8812f467b851a2d4009bc00fdc5553
https://doi.org/10.1158/0008-5472.22366371.v1
https://doi.org/10.1158/0008-5472.22366371.v1
Autor:
Michael L. Freeman, Joseph L. Roti Roti, James R. Lepock, Peter A. Crooks, Michael J. Borrelli, Robert G. Bristow, Ryuji Higashikubo, Nobuo Horikoshi, Jamil Sawani, Andrei Laszlo, Soumya Sasi, Venkatraj Muthusamy, Vijayakumar N. Sonar, Konjeti R. Sekhar
Radiation therapy combined with adjuvant hyperthermia has the potential to provide outstanding local-regional control for refractory disease. However, achieving therapeutic thermal dose can be problematic. In the current investigation, we used a chem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1baa1efcc3556d497da7d07a64c144ba
https://doi.org/10.1158/0008-5472.c.6495111
https://doi.org/10.1158/0008-5472.c.6495111
Autor:
Mouadh Benamar, Soumya Sasi, Michael L. Freeman, Konjeti R. Sekhar, Narsimha Reddy Penthala, Stephen R. Hann, Ramesh Balusu, Ling Geng, Peter A. Crooks, Amudhan Venkateswaran, Tarek Abbas
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 89:1106-1114
Purpose To test the hypothesis that small molecule targeting of nucleophosmin 1 (NPM1) represents a rational approach for radiosensitization. Methods and Materials Wilde-type and NPM1-deficient mouse embryo fibroblasts (MEFs) were used to determine w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::619241e9456f41025b1554c7a5935e78
https://doi.org/10.1016/j.ijrobp.2014.04.012
https://doi.org/10.1016/j.ijrobp.2014.04.012
Autor:
Michael L. Freeman, Girish Rachakonda, David B. Friedman, Amudhan Venkateswaran, Soumya Sasi, Peter A. Crooks, Alexandra J. Walsh, Melissa C. Skala, Konjeti R. Sekhar
Publikováno v:
Investigational New Drugs. 31:535-544
Targeting tumor vasculature represents a rational strategy for controlling cancer. (Z)-(+/-)-2-(1-benzylindol-3-ylmethylene)-1-azabicyclo[2.2.2]octan-3-ol (denoted VJ115) is a novel chemical entity that inhibits the enzyme ENOX1, a NADH oxidase. Gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d243670f62fecce93730a1d5cadf3048
https://doi.org/10.1007/s10637-012-9884-9
https://doi.org/10.1007/s10637-012-9884-9
Autor:
Konjeti R. Sekhar, Yerramreddy Thirupathi Reddy, Penthala Narsimha Reddy, Ling Geng, Soumya Sasi, Michael L. Freeman, Joseph L. Roti Roti, Peter A. Crooks, Girish Rachakonda, William Hayes McDonald, Kenneth J. Salleng, Robert P. Van Der Waal, Amudhan Venkateswaran
Publikováno v:
Clinical Cancer Research. 17:6490-6499
Purpose: Radiation therapy continues to be an important therapeutic strategy for providing definitive local/regional control of human cancer. However, oncogenes that harbor driver mutations and/or amplifications can compromise therapeutic efficacy. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::537bbc153536db3c2e9cfcfd53b53af2
https://doi.org/10.1158/1078-0432.ccr-11-1054
https://doi.org/10.1158/1078-0432.ccr-11-1054
Publikováno v:
Cancer Research. 68:364-368
The transcription factor nuclear factor erythroid-derived 2–related factor 2 (Nrf2) regulates induction of an extensive cellular stress response network when complexed with the cAMP-responsive element binding protein (CBP) at antioxidant response e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d0a649e7fa4fd02df16084fce3114ea
https://doi.org/10.1158/0008-5472.can-07-2170
https://doi.org/10.1158/0008-5472.can-07-2170