Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Soumya Palliyil"'
Autor:
Mohammad Arastoo, Lewis K. Penny, Richard Lofthouse, Aya Abdallah, Anna Abrahamsson, Pietro Marini, Valeria Melis, Gernot Riedel, Charles R. Harrington, Claude M. Wischik, Andrew Porter, Soumya Palliyil
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-20 (2024)
Abstract Background Recent advances in blood-based biomarker discovery are paving the way for simpler, more accessible diagnostic tools that can detect early signs of Alzheimer’s disease (AD). Recent successes in the development of amyloid-targetin
Externí odkaz:
https://doaj.org/article/3efb8c85249a4d3e81c8e65617f504f9
Autor:
Lewis K. Penny, Richard Lofthouse, Mohammad Arastoo, Andy Porter, Soumya Palliyil, Charles R. Harrington, Claude M. Wischik
Publikováno v:
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-14 (2024)
Abstract The use of biomarker-led clinical trial designs has been transformative for investigating amyloid-targeting therapies for Alzheimer’s disease (AD). The designs have ensured the correct selection of patients on these trials, supported targe
Externí odkaz:
https://doaj.org/article/73f382a2bce1401e95495cc3facd6bb0
Publikováno v:
Exploration of Immunology, Vol 1, Iss 5, Pp 440-460 (2021)
The coronavirus disease 2019 (COVID-19) results from the infection of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and primarily affects the respiratory tissue. Since first reported from Wuhan, China in December 2019, the virus has re
Externí odkaz:
https://doaj.org/article/7e4a5c9c8e4f428da8695b4db6802d25
Autor:
Alex Zabala-Findlay, Lewis K. Penny, Richard A. Lofthouse, Andrew J. Porter, Soumya Palliyil, Charles R. Harrington, Claude M. Wischik, Mohammad Arastoo
Publikováno v:
Cells, Vol 12, Iss 8, p 1184 (2023)
Objectives: With the development of new technologies capable of detecting low concentrations of Alzheimer’s disease (AD) relevant biomarkers, the idea of a blood-based diagnosis of AD is nearing reality. This study aims to consider the evidence of
Externí odkaz:
https://doaj.org/article/54645bfccaff4fddaeb74228191eca5f
Autor:
Tyng Hwey Tan, Elizabeth Patton, Carol A. Munro, Dora E. Corzo-Leon, Andrew J. Porter, Soumya Palliyil
Publikováno v:
Viruses, Vol 13, Iss 11, p 2201 (2021)
ORF3a has been identified as a viroporin of SARS-CoV-2 and is known to be involved in various pathophysiological activities including disturbance of cellular calcium homeostasis, inflammasome activation, apoptosis induction and disruption of autophag
Externí odkaz:
https://doaj.org/article/c10c6e519e564d23bd7c3db95d5ae027
Autor:
Mohammad Arastoo, Richard Lofthouse, Lewis K. Penny, Charles R. Harrington, Andy Porter, Claude M. Wischik, Soumya Palliyil
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 22, p 8673 (2020)
Despite continued efforts, there remain no disease-modifying drugs approved by the United States Food and Drug Administration (FDA) or European Medicines Agency (EMA) to combat the global epidemic of Alzheimer’s disease. Currently approved medicine
Externí odkaz:
https://doaj.org/article/b3dbc16acd4248b3ab5b13df823747b3
Autor:
Soumya Palliyil, Mark Mawer, Sami A. Alawfi, Lily Fogg, Tyng H. Tan, Giuseppe Buda De Cesare, Louise A. Walker, Donna M. MacCallum, Andrew J. Porter, Carol A. Munro
Publikováno v:
Antimicrobial Agents and Chemotherapy. 66
Monoclonal antibody (mAb)-based immunotherapies targeting systemic and deep-seated fungal infections are still in their early stages of development, with no licensed antifungal mAbs currently being available for patients at risk. The cell wall glycop
Autor:
Andrew J. Porter, Tyng Hwey Tan, Dora E Corzo-Leon, Carol A. Munro, Elizabeth Patton, Soumya Palliyil
Publikováno v:
Viruses
Viruses, Vol 13, Iss 2201, p 2201 (2021)
Viruses, Vol 13, Iss 2201, p 2201 (2021)
ORF3a has been identified as a viroporin of SARS-CoV-2 and is known to be involved in various pathophysiological activities including disturbance of cellular calcium homeostasis, inflammasome activation, apoptosis induction and disruption of autophag
Autor:
Mark Mawer, Soumya Palliyil, Lily Fogg, Giuseppe Buda De Cesare, Carol A. Munro, Louise A. Walker, Tyng H Tan, Andrew J. Porter, Sami Aqeel Alawfi, Donna M. MacCallum
MAb based immunotherapies targeting systemic and deep-seated fungal infections are still in their early stages of development with currently no licensed antifungal mAbs available for patients at risk. The cell wall glycoproteins of Candida albicans a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8c80a06a94b5f6d8b7ca6636b8691ca
https://doi.org/10.1101/2021.09.29.462385
https://doi.org/10.1101/2021.09.29.462385
Publikováno v:
Drug Design, Development and Therapy
Non-alcoholic steatohepatitis (NASH) is a progressive form of non-alcoholic fatty liver disease (NAFLD), characterized by chronic inflammation and accumulation of fat in liver tissue. Affecting estimated 35 million people globally, NASH is the most c