Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Soumya Deo"'
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Acinetobacter baumannii is classified as a top priority pathogen by the World Health Organization (WHO) because of its widespread resistance to all classes of antibiotics. This makes the need for understanding the mechanisms of resistance and virulen
Externí odkaz:
https://doaj.org/article/07498f62c38040a0881fdeab9d0dea99
Autor:
Edis Dzananovic, Astha, Grzegorz Chojnowski, Soumya Deo, Evan P Booy, Pauline Padilla-Meier, Kevin McEleney, Janusz M Bujnicki, Trushar R Patel, Sean A McKenna
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186849 (2017)
Highly structured RNA derived from viral genomes is a key cellular indicator of viral infection. In response, cells produce the interferon inducible RNA-dependent protein kinase (PKR) that, when bound to viral dsRNA, phosphorylates eukaryotic initiat
Externí odkaz:
https://doaj.org/article/84fd847862b04e2c823b1f4366e567eb
Autor:
Soumya Deo, Trushar R Patel, Edis Dzananovic, Evan P Booy, Khalid Zeid, Kevin McEleney, Stephen E Harding, Sean A McKenna
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92545 (2014)
West Nile virus (WNV) has a positive sense RNA genome with conserved structural elements in the 5' and 3' -untranslated regions required for polyprotein production. Antiviral immunity to WNV is partially mediated through the production of a cluster o
Externí odkaz:
https://doaj.org/article/c340459956e04d00b0b3f472c7a1ecaf
Publikováno v:
Biochemistry and Cell Biology. 98:70-82
Human 2′–5′ oligoadenylate synthetases (OAS) are a family of interferon-inducible proteins that, upon activation by double-stranded RNA, polymerize ATP into 2′–5′ linked oligoadenylates. In this study, we probed the RNA cofactor specifici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14db81eb4a3d88bc3bbd2fc823d8cb01
https://doi.org/10.1139/bcb-2019-0060
https://doi.org/10.1139/bcb-2019-0060
Publikováno v:
Biotechnology Advances. 59:107968
Antimicrobial peptides (AMPs) found in a wide range of animal, insect, and plant species are host defense peptides forming an integral part of their innate immunity. Although the exact mode of action of some AMPs is yet to be deciphered, many exhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fd80544b7bc612efc49ebe5e9f1ef2c
https://doi.org/10.1016/j.biotechadv.2022.107968
https://doi.org/10.1016/j.biotechadv.2022.107968
Impact of the structural integrity of the three-way junction of adenovirus VAI RNA on PKR inhibition
Autor:
Kevin McEleney, Edis Dzananovic, Astha, Evan P. Booy, Trushar R. Patel, Soumya Deo, Sean A. McKenna, Pauline Padilla-Meier, Janusz M. Bujnicki, Grzegorz Chojnowski
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 10, p e0186849 (2017)
PLoS ONE, Vol 12, Iss 10, p e0186849 (2017)
Highly structured RNA derived from viral genomes is a key cellular indicator of viral infection. In response, cells produce the interferon inducible RNA-dependent protein kinase (PKR) that, when bound to viral dsRNA, phosphorylates eukaryotic initiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10e339d022484a5818679c573bcac00e
https://pubmed.ncbi.nlm.nih.gov/29053745
https://pubmed.ncbi.nlm.nih.gov/29053745
Autor:
Ewan K.S. McRae, Jörg Stetefeld, Edis Dzananovic, Markus Meier, Ryan Howard, Sean A. McKenna, Soumya Deo, Emmanuel O. Ariyo, Evan P. Booy
Publikováno v:
The Journal of biological chemistry. 291(10)
RNA helicase associated with AU-rich element (RHAU) is an ATP-dependent RNA helicase that demonstrates high affinity for quadruplex structures in DNA and RNA. To elucidate the significance of these quadruplex-RHAU interactions, we have performed RNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::587838cb676f5c55acee6ec17ee041aa
https://pubmed.ncbi.nlm.nih.gov/26740632
https://pubmed.ncbi.nlm.nih.gov/26740632
Autor:
George G. Zhanel, Dinesh M. Fernando, Sean A. McKenna, Frank Schweizer, Ayush Kumar, Bala Kishan Gorityala, Goutam Guchhait, Soumya Deo
Publikováno v:
Angewandte Chemie (International ed. in English). 55(2)
The use of adjuvants that rescue antibiotics against multidrug-resistant (MDR) pathogens is a promising combination strategy for overcoming bacterial resistance. While the combination of β-lactam antibiotics and β-lactamase inhibitors has been succ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a135c227eb9595bc59e092c9da204e
https://pubmed.ncbi.nlm.nih.gov/26610184
https://pubmed.ncbi.nlm.nih.gov/26610184
Autor:
Trushar R. Patel, Edis Dzananovic, Amit Koul, Sean A. McKenna, Kevin McEleney, Janusz M. Bujnicki, Grzegorz Chojnowski, Soumya Deo
Publikováno v:
Journal of structural biology. 190(2)
2′ 5′-Oligoadenylate synthetases (OAS) are interferon-stimulated proteins that act in the innate immune response to viral infection. Upon binding viral double-stranded RNA, OAS enzymes produce 2′-5′-linked oligoadenylates that stimulate RNase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7486d95d415a82cbaeb7211686a1f40
https://pubmed.ncbi.nlm.nih.gov/25871524
https://pubmed.ncbi.nlm.nih.gov/25871524
Autor:
Evan P. Booy, Khalid Zeid, Edis Dzananovic, Trushar R. Patel, Sean A. McKenna, Stephen E. Harding, Kevin McEleney, Soumya Deo
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92545 (2014)
PLoS ONE
PLoS ONE
West Nile virus (WNV) has a positive sense RNA genome with conserved structural elements in the 5′ and 3′ -untranslated regions required for polyprotein production. Antiviral immunity to WNV is partially mediated through the production of a clust
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bed937c467b48fa6ad390941246551d
http://europepmc.org/articles/PMC3961380?pdf=render
http://europepmc.org/articles/PMC3961380?pdf=render