Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Soumya, Mitra"'
Autor:
Radhika Narain, Ian Nessler, Paul L. Richardson, Jamie E. Erickson, Yuzhen Wang, Jacqueline Ferri, Heather L. Knight, Shaughn H. Bryant, Lucy A. Phillips, Liang Zhang, Soumya Mitra
Publikováno v:
npj Imaging, Vol 2, Iss 1, Pp 1-11 (2024)
Abstract In this work, the impact of physicochemical modifications on pharmacokinetics and in vivo targeting of a small molecule fibroblast activation protein inhibitor (FAPI) imaging ligand in a murine model of rheumatoid arthritis was evaluated. Wh
Externí odkaz:
https://doaj.org/article/821384118fe54bc18bf98f999d4cbfe8
Autor:
Bornika Chattaraj, Arijit Nandi, Anwesha Das, Arun Baidya, Sourav Mahata, Aritra Chowdhury, Soumya Mitra, Sumon Roy, Subrata Chakraborty, Yadu Nandan Dey
Publikováno v:
Food Chemistry Advances, Vol 2, Iss , Pp 100287- (2023)
Enhydra fluctuans Lour. is consumed by various tribes in their ethnomedicinal practices for the treatment of kidney stones and urinary problems. However, no scientific studies were conducted to evaluate its effect on crystal growth. Hence, the presen
Externí odkaz:
https://doaj.org/article/45052fd555274a6da2709dc717a0b789
Autor:
Victor Z. Sun, Terry L. Melim, Soumya Mitra, Jamie E. Erickson, Shaughn H. Bryant, Avery Farnham, Susan Westmoreland, Heather Knight, Liang Zhang, Wendy Ritacco, Kristoff Homan, Lorenzo Benatuil, Annette J. Schwartz Sterman, Andrew D. Goodearl
Publikováno v:
Advances in Rheumatology, Vol 62, Iss 1, Pp 1-11 (2022)
Abstract Objectives To assess the ability of monoclonal antibodies (mAbs) specific for fibronectin extra-domain A (FnEDA) to target diseased tissues of mouse collagen induced arthritis (mCIA) models. To explore the parameters of the targeting exhibit
Externí odkaz:
https://doaj.org/article/5531f8c606f74f098bd7fe9145f870a8
Autor:
Audrey E. Lord, Liang Zhang, Jamie E. Erickson, Shaughn Bryant, Christine M. Nelson, Stephanie M. Gaudette, Lucy A. Phillips, Annette J. Schwartz Sterman, Soumya Mitra
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract A painful, chronic condition, Rheumatoid Arthritis, is marked by bone erosion and soft tissue swelling at the joint. As treatments are investigated in pre-clinical models, characterizing disease progression is integral to assessing treatment
Externí odkaz:
https://doaj.org/article/3d3de82d1b0e43f0b6d7e296c1c4762a
Autor:
Shuvam Sar, Soumya Mitra, Parthasarathi Panda, Subhash C. Mandal, Nilanjan Ghosh, Amit Kumar Halder, Maria Natalia D. S. Cordeiro
Publikováno v:
Molecules, Vol 28, Iss 17, p 6379 (2023)
Human soluble epoxide hydrolase (sEH), a dual-functioning homodimeric enzyme with hydrolase and phosphatase activities, is known for its pivotal role in the hydrolysis of epoxyeicosatrienoic acids. Inhibitors targeting sEH have shown promising potent
Externí odkaz:
https://doaj.org/article/6fdc234186bb460092e9e2f7aaddae48
Autor:
Bornika Chattaraj, Pukar Khanal, Arijit Nandi, Anwesha Das, Amit Sharma, Soumya Mitra, Yadu Nandan Dey
Publikováno v:
Journal of Biomolecular Structure and Dynamics. :1-11
In view of the ethno medicinal use of Enhydra fluctuans for the treatment of kidney stones; the present study aimed to elucidate the molecular mechanisms involved in the amelioration of nephrolithiasis through a network pharmacology approach. The phy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::970e39bcc007f4c3692a0753b99201ce
https://doi.org/10.1080/07391102.2023.2189476
https://doi.org/10.1080/07391102.2023.2189476
Autor:
Ningyan Hu, Layal Antoury, Timothy M. Baran, Soumya Mitra, C. Frank Bennett, Frank Rigo, Thomas H. Foster, Thurman M. Wheeler
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Myotonic dystrophy type 1 (DM1) is associated with aberrant transcript splicing. Here, the authors develop a transgenic mouse model expressing a bi-chromatic reporter system that allows non-invasive monitoring of splicing of a transcript altered in D
Externí odkaz:
https://doaj.org/article/b1565fb81d1d487aac6b620c6b16e1b3
Autor:
R. Angelo De Claro, Marc R. Theoret, Richard Pazdur, Kirsten B. Goldberg, Adam N. Maung, Sherita McLamore, Anamitro Banerjee, Rakhi Shah, Djelila Mezaache, Paresma Patel, Yuching Yang, Lian Ma, Olanrewaju O. Okusanya, Jonathon Vallejo, Soumya Mitra, Ramadevi Gudi, Ying-Hong Wang, Ruo-Jing Li, Alexei Ionan, Robert Q. Le, Donna Przepiorka
Supplementary Data from FDA Approval Summary: Belumosudil for Adult and Pediatric Patients 12 Years and Older with Chronic GvHD after Two or More Prior Lines of Systemic Therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ee0c0967a3851e2bc53147f32148123
https://doi.org/10.1158/1078-0432.22486526
https://doi.org/10.1158/1078-0432.22486526
Autor:
R. Angelo De Claro, Marc R. Theoret, Richard Pazdur, Kirsten B. Goldberg, Adam N. Maung, Sherita McLamore, Anamitro Banerjee, Rakhi Shah, Djelila Mezaache, Paresma Patel, Yuching Yang, Lian Ma, Olanrewaju O. Okusanya, Jonathon Vallejo, Soumya Mitra, Ramadevi Gudi, Ying-Hong Wang, Ruo-Jing Li, Alexei Ionan, Robert Q. Le, Donna Przepiorka
On July 16, 2021, the FDA approved belumosudil, a kinase inhibitor, for adult and pediatric patients 12 years and older with chronic GvHD (cGvHD) after failure of at least two prior lines of systemic therapy. Approval was based on the results of Stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cf5ad9b338cb810d274cde6114ea10c
https://doi.org/10.1158/1078-0432.c.6532340
https://doi.org/10.1158/1078-0432.c.6532340
Major depressive disorders (MDD) pose major health burdens globally. Currently available medications have their limitations due to serious adverse effects, long latency periods as well as resistance. Considering the highly complicated pathological na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8747e6ad218a6698194cbd43494f08b