Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Soumya, Maity"'
Autor:
Akshar Patel, Matthew Simkulet, Soumya Maity, Manigandan Venkatesan, Anastasios Matzavinos, Muniswamy Madesh, B. Rita Alevriadou
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract The mitochondrial calcium (Ca2+) uniporter (MCU) channel is responsible for mitochondrial Ca2+ influx. Its expression was found to be upregulated in endothelial cells (ECs) under cardiovascular disease conditions. Since the role of MCU in re
Externí odkaz:
https://doaj.org/article/60992396b0f048ee90a689948b2e1637
Autor:
Travis R. Madaris, Manigandan Venkatesan, Soumya Maity, Miriam C. Stein, Neelanjan Vishnu, Mridula K. Venkateswaran, James G. Davis, Karthik Ramachandran, Sukanthathulse Uthayabalan, Cristel Allen, Ayodeji Osidele, Kristen Stanley, Nicholas P. Bigham, Terry M. Bakewell, Melanie Narkunan, Amy Le, Varsha Karanam, Kang Li, Aum Mhapankar, Luke Norton, Jean Ross, M. Imran Aslam, W. Brian Reeves, Brij B. Singh, Jeffrey Caplan, Justin J. Wilson, Peter B. Stathopulos, Joseph A. Baur, Muniswamy Madesh
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112155- (2023)
Summary: The most abundant cellular divalent cations, Mg2+ (mM) and Ca2+ (nM-μM), antagonistically regulate divergent metabolic pathways with several orders of magnitude affinity preference, but the physiological significance of this competition rem
Externí odkaz:
https://doaj.org/article/324fd2ad3fb9463fa4701a04cb364947
Autor:
Akshar Patel, Julia G. Pietromicca, Manigandan Venkatesan, Soumya Maity, Jonathan E. Bard, Muniswamy Madesh, B. Rita Alevriadou
Publikováno v:
Physiological Reports, Vol 11, Iss 3, Pp n/a-n/a (2023)
Abstract Mitochondrial calcium (mCa2+) uptake occurs via the Mitochondrial Ca2+ Uniporter (MCU) complex and plays a critical role in mitochondrial dynamics, mitophagy, and apoptosis. MCU complex activity is in part modulated by the expression of its
Externí odkaz:
https://doaj.org/article/baa17e0107a140e3a0e19ab36864111a
Autor:
Karthik Ramachandran, Soumya Maity, Alagar R. Muthukumar, Soundarya Kandala, Dhanendra Tomar, Tarek Mohamed Abd El-Aziz, Cristel Allen, Yuyang Sun, Manigandan Venkatesan, Travis R. Madaris, Kevin Chiem, Rachel Truitt, Neelanjan Vishnu, Gregory Aune, Allen Anderson, Luis Martinez, Wenli Yang, James D. Stockand, Brij B. Singh, Subramanya Srikantan, W. Brian Reeves, Muniswamy Madesh
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103722- (2022)
Summary: SARS-CoV-2 is a newly identified coronavirus that causes the respiratory disease called coronavirus disease 2019 (COVID-19). With an urgent need for therapeutics, we lack a full understanding of the molecular basis of SARS-CoV-2-induced cell
Externí odkaz:
https://doaj.org/article/6b278b5fe84c471b8072bb9b105a52c6
Autor:
Viviane Nascimento Da Conceicao, Yuyang Sun, Karthik Ramachandran, Arun Chauhan, Amritha Raveendran, Manigandan Venkatesan, Bony DeKumar, Soumya Maity, Neelanjan Vishnu, George A. Kotsakis, Paul F. Worley, Donald L. Gill, Bibhuti B. Mishra, Muniswamy Madesh, Brij B. Singh
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103339- (2021)
Summary: Transformation of naive macrophages into classically (M1) or alternatively (M2) activated macrophages regulates the inflammatory response. Here, we identified that distinct Ca2+ entry channels determine the IFNγ-induced M1 or IL-4-induced M
Externí odkaz:
https://doaj.org/article/07366b1458be4b4bbeed13ff5fe16ed8
Autor:
Michael D. Wetzel, Kristen Stanley, Soumya Maity, Muniswamy Madesh, Jean C. Bopassa, Alaa S. Awad
Publikováno v:
Physiological Reports, Vol 9, Iss 5, Pp n/a-n/a (2021)
Abstract Recently we showed that homoarginine supplementation confers kidney protection in diabetic mouse models. In this study we tested whether the protective effect of homoarginine is nitric oxide synthase‐3 (NOS3)‐independent in diabetic neph
Externí odkaz:
https://doaj.org/article/f707223766d44a32a1abf424534cbdad
Autor:
Falguni Das, Nandini Ghosh‐Choudhury, Soumya Maity, Balakuntalam S. Kasinath, Goutam Ghosh Choudhury
Publikováno v:
FEBS Letters. 597:1300-1316
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75e26e928f47a66b5ce3160de58d25c3
https://doi.org/10.1002/1873-3468.14599
https://doi.org/10.1002/1873-3468.14599
Autor:
Michael D. Wetzel, Kristen Stanley, Wei Wei Wang, Soumya Maity, Muniswamy Madesh, W. Brian Reeves, Alaa S. Awad
Publikováno v:
JCI Insight, Vol 5, Iss 19 (2020)
Fibrosis is the final common pathway in the pathophysiology of most forms of chronic kidney disease (CKD). As treatment of renal fibrosis still remains largely supportive, a refined understanding of the cellular and molecular mechanisms of kidney fib
Externí odkaz:
https://doaj.org/article/483b48be22c64c11a53ed382f43916ae
Autor:
Akshar, Patel, Matthew, Simkulet, Soumya, Maity, Manigandan, Venkatesan, Anastasios, Matzavinos, Muniswamy, Madesh, B Rita, Alevriadou
Publikováno v:
Scientific reports. 12(1)
The mitochondrial calcium (Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d0eb53761a5d9353ff369f5401c14ff9
https://pubmed.ncbi.nlm.nih.gov/36476944
https://pubmed.ncbi.nlm.nih.gov/36476944
Autor:
Peter J. Oates, Soumya Maity, Guanshi Zhang, Xianlin Han, Kumar Sharma, Satoshi Miyamoto, David J. Hall, Muniswamy Madesh
Publikováno v:
Journal of Biological Chemistry. 295:7249-7260
Exposure to chronic hyperglycemia because of diabetes mellitus can lead to development and progression of diabetic kidney disease (DKD). We recently reported that reduced superoxide production is associated with mitochondrial dysfunction in the kidne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5650a78a7b26af04de84b6a7040cca47
https://doi.org/10.1074/jbc.ra119.011110
https://doi.org/10.1074/jbc.ra119.011110