Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Soumita Goswami"'
Autor:
Gregory Caleb Howard, Jing Wang, Kristie L Rose, Camden Jones, Purvi Patel, Tina Tsui, Andrea C Florian, Logan Vlach, Shelly L Lorey, Brian C Grieb, Brianna N Smith, Macey J Slota, Elizabeth M Reynolds, Soumita Goswami, Michael R Savona, Frank M Mason, Taekyu Lee, Stephen Fesik, Qi Liu, William P Tansey
Publikováno v:
eLife, Vol 12 (2024)
The chromatin-associated protein WD Repeat Domain 5 (WDR5) is a promising target for cancer drug discovery, with most efforts blocking an arginine-binding cavity on the protein called the ‘WIN’ site that tethers WDR5 to chromatin. WIN site inhibi
Externí odkaz:
https://doaj.org/article/843d9e309e8c4e569cdd20374b77da61
Publikováno v:
Brain, Behavior, and Immunity. 100:194-210
Alzheimer's disease (AD) is mainly characterized by amyloid beta (Aβ) plaque deposition and neurofibrillary tangle formation due to tau hyperphosphorylation. It has been shown that astrocytes respond to these pathologies very early and exert either
Autor:
Kevin B. Teuscher, Somenath Chowdhury, Kenneth M. Meyers, Jianhua Tian, Jiqing Sai, Mayme Van Meveren, Taylor M. South, John L. Sensintaffar, Tyson A. Rietz, Soumita Goswami, Jing Wang, Brian C. Grieb, Shelly L. Lorey, Gregory C. Howard, Qi Liu, William J. Moore, Gordon M. Stott, William P. Tansey, Taekyu Lee, Stephen W. Fesik
Publikováno v:
Proceedings of the National Academy of Sciences. 120
WD repeat domain 5 (WDR5) is a core scaffolding component of many multiprotein complexes that perform a variety of critical chromatin-centric processes in the nucleus. WDR5 is a component of the mixed lineage leukemia MLL/SET complex and localizes MY
Publikováno v:
ISRN Pharmaceutics
The aim of this investigation was to develop and optimize bisoprolol fumarate matrix tablets for sustained release application by response surface methodology based on 23 factorial design. The effects of the amounts of calcium alginate, HPMC K4M, and
Autor:
Sudipta Chakraborty, Avijit Dey, Suvrotoa Mitra, Debakana Banerjee, Soumita Goswami, Nabanita Ghosh, Navodipa Bhattacharya, Elizabeth Mahapatra, Dishari Dasgupta
Publikováno v:
Tissuecell. 49(2 Pt)
Complete or partial depletion of resource in a freshwater habitat is a common phenomenon. As a consequence, aquatic fauna including bivalve molluscs may be exposed to dietary stress on a seasonal basis. Haemocyte based innate immune profile of the fr
Publikováno v:
Asian Journal of Pharmaceutical and Clinical Research. 11:211
Objective: PITC-2 was isolated from the methanolic root extract of tissue cultured medicinal plant Pluchea indica (L.) Less. PITC-2 is a thiophene derivative which is 2-(Prop-1-ynyl)-5(5,6-dihydroxyhexa-1,3-diynyl)-thiophene. The main objective of th
Autor:
Howard, Gregory Caleb, Jing Wang, Rose, Kristie L., Jones, Camden, Patel, Purvi, Tsui, Tina, Florian, Andrea C., Vlach, Logan, Lorey, Shelly L., Grieb, Brian C., Smith, Brianna N., Slota, Macey J., Reynolds, Elizabeth M., Goswami, Soumita, Savona, Michael R., Mason, Frank M., Taekyu Lee, Fesik, Stephen, Qi Liu, Tansey, William P.
Publikováno v:
eLife; 4/29/2024, p1-42, 42p
Publikováno v:
Hematology Week; 5/14/2024, p1529-1529, 1p