Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Soumeya, Abed"'
Autor:
Rodrigo Jiménez-Saiz, Varun C. Anipindi, Heather Galipeau, Yosef Ellenbogen, Roopali Chaudhary, Joshua F. Koenig, Melissa E. Gordon, Tina D. Walker, Talveer S. Mandur, Soumeya Abed, Alison Humbles, Derek K. Chu, Jonas Erjefält, Kjetil Ask, Elena F. Verdú, Manel Jordana
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Eosinophils have emerged as multifaceted cells that contribute to tissue homeostasis. However, the impact of the microbiota on their frequency and function at mucosal sites remains unclear. Here, we investigated the role of the microbiota in the regu
Externí odkaz:
https://doaj.org/article/5103ca5ce415466b80ee467924a56408
Autor:
Rohan R. Nadkarni, Soumeya Abed, Brian J. Cox, Sonam Bhatia, Jennifer T. Lau, Michael G. Surette, Jonathan S. Draper
Publikováno v:
Stem Cell Reports, Vol 9, Iss 3, Pp 897-912 (2017)
Intestinal organoids derived from human pluripotent stem cells (hPSCs) are valuable in vitro research models that enable simplified access to human gastrointestinal tissues. Here, we report the in vitro generation of enterospheres (hEnS) from hPSC-de
Externí odkaz:
https://doaj.org/article/41d69864262a46b59e95fb751b24aedd
Autor:
Eleanor Luce, Clara Steichen, Soumeya Abed, Anne Weber, Philippe Leboulch, Leila Maouche-Chrétien, Anne Dubart-Kupperschmitt
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 18; Pages: 10861
The use of primary cells in human liver therapy is limited by a lack of cells. Induced pluripotent stem cells (iPSCs) represent an alternative to primary cells as they are infinitely expandable and can be differentiated into different liver cell type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b984844908e30cabbf9e41a1fd7fe8
https://pubmed.ncbi.nlm.nih.gov/36142774
https://pubmed.ncbi.nlm.nih.gov/36142774
Autor:
Spencer Revill, Pierre-Simon Bellaye, Martin Kolb, Karun Tandon, Kjetil Ask, Nathan Hambly, Ehab A. Ayaub, Jean-Claude Cutz, Philipp Kolb, Asghar Naqvi, Tamana Yousof, Martha M. Vaughan, Jiro Kato, Safaa Naiel, Megan Vierhout, Soumeya Abed, Anmar Ayoub, Joel Moss, Manreet Padwal, Anna Dvorkin-Gheva, Victor Tat, Olivia Mekhael
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 64:235-246
Pulmonary fibrosis is a progressive lung disease characterized by myofibroblast accumulation and excessive extracellular matrix deposition. Endoplasmic reticulum (ER) stress initiates the unfolded protein response (UPR), a cellular stress response pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::813e63ee9e89068286356ebacfc0eb8a
https://doi.org/10.1165/rcmb.2020-0121oc
https://doi.org/10.1165/rcmb.2020-0121oc
Autor:
Olivia Mekhael, Manreet Padwal, Anna Dvorkin-Gheva, Anmar Ayoub, Tamana Yousof, Soumeya Abed, Safaa Naiel, Victor Tat, Megan Vierhout, Kjetil Ask
Publikováno v:
Chest. 157:1207-1220
Chronic lung disease accounts for a significant global burden with respect to death, disability, and health-care costs. Due to the heterogeneous nature and limited treatment options for these diseases, it is imperative that the cellular and molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81945c6cf8e20813e4ea37e776d3d1bc
https://doi.org/10.1016/j.chest.2019.11.009
https://doi.org/10.1016/j.chest.2019.11.009
Autor:
Soumeya Abed, Alisa Tubsuwan, Porntip Chaichompoo, In Hyun Park, Alice Pailleret, Aïssa Benyoucef, Lucie Tosca, Edouard De Dreuzy, Anais Paulard, Marine Granger-Locatelli, Francis Relouzat, Stéphane Prost, Gerard Tachdjian, Suthat Fucharoen, George Q. Daley, Emmanuel Payen, Stany Chrétien, Philippe Leboulch, Leïla Maouche-Chrétien
Publikováno v:
Haematologica, Vol 100, Iss 10 (2015)
Externí odkaz:
https://doaj.org/article/e21fa93c435d413c97dd9e62cfafade1
Autor:
Olivia, Mekhael, Safaa, Naiel, Megan, Vierhout, Aaron I, Hayat, Spencer D, Revill, Soumeya, Abed, Mark D, Inman, Martin R J, Kolb, Kjetil, Ask
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2299
The drug discovery pipeline, from discovery of therapeutic targets through preclinical and clinical development phases, to an approved product by health authorities, is a time-consuming and costly process, where a lead candidates' success at reaching
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eb9548e6fc6906a4c91a39a21a19091b
https://pubmed.ncbi.nlm.nih.gov/34028751
https://pubmed.ncbi.nlm.nih.gov/34028751
Autor:
Olivia Mekhael, Aaron Hayat, Martin Kolb, Spencer Revill, Soumeya Abed, Kjetil Ask, Safaa Naiel, Megan Vierhout, Mark D. Inman
Publikováno v:
Methods in Molecular Biology ISBN: 9781071613818
The drug discovery pipeline, from discovery of therapeutic targets through preclinical and clinical development phases, to an approved product by health authorities, is a time-consuming and costly process, where a lead candidates' success at reaching
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e813604e5b1fdd8968e4532c3ee33f7
https://doi.org/10.1007/978-1-0716-1382-5_21
https://doi.org/10.1007/978-1-0716-1382-5_21
Publikováno v:
Chest. 153:994-1003
The epithelial cells lining the mammalian lung are subjected to constant interaction with the external environment, necessitating robust regeneration strategies to deal with cell loss due to natural turnover or damage arising from inhaled agents or d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b644a6e1f5ed04294e1a48dbef1ef27
https://doi.org/10.1016/j.chest.2017.07.021
https://doi.org/10.1016/j.chest.2017.07.021
Autor:
Aaron Hayat, Victor Tat, Safaa Naiel, Nickolas Serniuck, Kjetil Ask, Megan Vierhout, Olivia Mekhael, Anthony F. Rullo, Rebecca C. Turner, Soumeya Abed
Publikováno v:
Biochemical Pharmacology. 190:114577
Non-targeted drug delivery systems have several limitations including the decreased bioavailability of the drug, poor stability and rapid clearance in addition to off-target distribution. Cell-specific targeted delivery approaches promise to overcome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9404dc72e8847ff4fa2078d8112772a
https://doi.org/10.1016/j.bcp.2021.114577
https://doi.org/10.1016/j.bcp.2021.114577