Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Soumendra K. Karmahapatra"'
Autor:
Sanjay Adhikari, Rabindra Roy, Soumendra K. Karmahapatra, Aykut Üren, Priyanka Dhopeshwarkar, Hadi Elias, R. Scott Williams, Stephen W. Byers
Publikováno v:
Analytical Biochemistry. 416:112-116
Tyrosyl DNA phosphodiesterase 2 (TDP2), a newly discovered enzyme that cleaves 5′-phosphotyrosyl bonds, is a potential target for chemotherapy. TDP2 possesses both 3′- and 5′-tyrosyl-DNA phosphodiesterase activity, which is generally measured i
Autor:
Partha S. Mitra, Raja Mazumder, Pooja Khatkar, Nikhil Nuthalapati, Soumendra K. Karmahapatra, Monica Dixon, Mahandranauth A. Chetram, Sanjay Adhikari, Suhani Gupta, Jordan Woodrick, Christopher A. Loffredo, Praveen Varma Manthena, Aykut Üren, Sivanesan Dakshanamurthy, Ganga Narasimhan, Rabindra Roy
Human N-methylpurine DNA glycosylase (hMPG) initiates base excision repair of a number of structurally diverse purine bases including 1,N(6)-ethenoadenine, hypoxanthine, and alkylation adducts in DNA. Genetic studies discovered at least eight validat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::900c07e96472f2f42d006cbcf16e38c5
https://europepmc.org/articles/PMC4335234/
https://europepmc.org/articles/PMC4335234/
Autor:
Eric Glasgow, Stephen W. Byers, Soumendra K. Karmahapatra, Sanjay Adhikari, Tejaswita M. Karve, Aykut Üren, Sanjona Bandyopadhyay, Praveen Varma Manthena, Jordan Woodrick, Tapas Saha
Publikováno v:
BMC Research Notes, Vol 5, Iss 1, p 134 (2012)
BMC Research Notes
BMC Research Notes
Background Topo-poisons can produce an enzyme-DNA complex linked by a 3'- or 5'-phosphotyrosyl covalent bond. 3'-phosphotyrosyl bonds can be repaired by tyrosyl DNA phosphodiesterase-1 (TDP1), an enzyme known for years, but a complementary human enzy