Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Soumen Kahali"'
Autor:
Soumen Kahali, Bhaswati Sarcar, Bin Fang, Eli S. Williams, John M. Koomen, Philip J. Tofilon, Prakash Chinnaiyan
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 12, Iss 1, Pp 80-86 (2010)
Histone deacetylase (HDAC) inhibitors represent an emerging class of anticancer agents progressing through clinical trials. Although their primary target is thought to involve acetylation of core histones, several nonhistone substrates have been iden
Externí odkaz:
https://doaj.org/article/3f3d803b028f4ec4b5fe652865305d84
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52265 (2012)
Rapidly growing tumors require efficient means to allow them to adapt to fluctuating microenvironments consisting of hypoxia, nutrient deprivation, and acidosis. The unfolded protein response (UPR) represents a defense mechanism allowing cells to res
Externí odkaz:
https://doaj.org/article/44a6e7442dad41379aded3d0f72f4aa8
Autor:
Prakash Chinnaiyan, Elizabeth Kensicki, Klaus-Peter Adam, Joseph J. Johnson, Zhigang Yuan, Soumen Kahali, Bhaswati Sarcar, Antony Prabhu
PDF file - 131K, (A) CSA attenuates oxygen consumption rate (OCR) in U251 stable CDO knockdown cells. (B) DCA increases OCR in U251 cells. (C) Immunofluorescent analysis of mitochondrial potential using the JC-1 assay. (D) CSA does not influence OCR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a7699c4978d97fdd1506a4d8f80474
https://doi.org/10.1158/0008-5472.22401425
https://doi.org/10.1158/0008-5472.22401425
Autor:
Robert Gillies, Peter Forsyth, Xiaotao Qu, Steven Eschrich, Soumen Kahali, Bhaswati Sarcar, Antony Prabhu, Gregory Bloom, Elizabeth Kensicki, Prakash Chinnaiyan
PDF file - 69K, Table S1. Tumor grade and histology of samples used for global metabolomic profiling. Table S2. Metabolites making up the identified metabolomic profiles that demonstrated statistical significance in malignant glioma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10c84d1510d5381907a4a1da626b5141
https://doi.org/10.1158/0008-5472.22394328
https://doi.org/10.1158/0008-5472.22394328
Autor:
Robert Gillies, Peter Forsyth, Xiaotao Qu, Steven Eschrich, Soumen Kahali, Bhaswati Sarcar, Antony Prabhu, Gregory Bloom, Elizabeth Kensicki, Prakash Chinnaiyan
PDF file - 224K, Transcriptional pathways associated with metabolic pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09686644b5291c29fd67c3e8eb471d6d
https://doi.org/10.1158/0008-5472.22394331.v1
https://doi.org/10.1158/0008-5472.22394331.v1
Autor:
Prakash Chinnaiyan, Elizabeth Kensicki, Klaus-Peter Adam, Joseph J. Johnson, Zhigang Yuan, Soumen Kahali, Bhaswati Sarcar, Antony Prabhu
PDF file - 124K, CSA concentrations in GBM. (A) CSA was quantified in GBM using targeted UHPLC-MS/MS and levels were correlated with relative CSA levels obtained from global metabolomic studies. (B) Representative chromatograph of a tissue sample (10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f3f63889cfe54edee635a84591dd57f
https://doi.org/10.1158/0008-5472.22401437.v1
https://doi.org/10.1158/0008-5472.22401437.v1
Autor:
Prakash Chinnaiyan, Elizabeth Kensicki, Klaus-Peter Adam, Joseph J. Johnson, Zhigang Yuan, Soumen Kahali, Bhaswati Sarcar, Antony Prabhu
PDF file - 53K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88fef58d0a6a9cb44d527494f0cbfb2a
https://doi.org/10.1158/0008-5472.22401416
https://doi.org/10.1158/0008-5472.22401416
Autor:
Prakash Chinnaiyan, Elizabeth Kensicki, Klaus-Peter Adam, Joseph J. Johnson, Zhigang Yuan, Soumen Kahali, Bhaswati Sarcar, Antony Prabhu
PDF file - 94K, CSA modulates mitochondrial function in GBM cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36434d61eef5904f59e5354e09a7061b
https://doi.org/10.1158/0008-5472.22401431.v1
https://doi.org/10.1158/0008-5472.22401431.v1
Autor:
Robert Gillies, Peter Forsyth, Xiaotao Qu, Steven Eschrich, Soumen Kahali, Bhaswati Sarcar, Antony Prabhu, Gregory Bloom, Elizabeth Kensicki, Prakash Chinnaiyan
PDF file - 609K, Kruskal-Wallis test for transciptional differences in metabolic subtypes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aced02841c66e18e6adf32ce8c0a8b66
https://doi.org/10.1158/0008-5472.22394334
https://doi.org/10.1158/0008-5472.22394334
Autor:
Prakash Chinnaiyan, Elizabeth Kensicki, Klaus-Peter Adam, Joseph J. Johnson, Zhigang Yuan, Soumen Kahali, Bhaswati Sarcar, Antony Prabhu
PDF file - 53K, Top ten metabolites with highest fold increases (red) and decreases (green) in GBM when compared to Grade II glioma.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::179ed789357ba7e555759ec22bbc9fa4
https://doi.org/10.1158/0008-5472.22401413
https://doi.org/10.1158/0008-5472.22401413