Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Soumaya Benjelloun"'
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 16, Iss 12, Pp 2992-3000 (2020)
The current Coronavirus Disease 2019 (COVID-19) pandemic is causing great alarm around the world. The pathogen for COVID-19 – severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – is the seventh known coronavirus to cause pneumonia in hu
Externí odkaz:
https://doaj.org/article/bef6b860e5eb4d4c92b129bb8b603de8
Autor:
Eirini Karamichali, Hajar Chihab, Athanassios Kakkanas, Agnes Marchio, Timokratis Karamitros, Vasiliki Pogka, Agoritsa Varaklioti, Antonis Kalliaropoulos, Beatrice Martinez-Gonzales, Pelagia Foka, Ioannis Koskinas, Andreas Mentis, Soumaya Benjelloun, Pascal Pineau, Urania Georgopoulou
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Defective interfering (DI) RNAs have been detected in several human viruses. HCV in-frame deletions mutants (IFDMs), missing mainly the envelope proteins, have been found in patient sera and liver tissues. IFDMs replicate independently and can be tra
Externí odkaz:
https://doaj.org/article/47876926690842079467ee0150f391e1
Autor:
Abdellah Akil, Juan Peng, Mohyeddine Omrane, Claire Gondeau, Christophe Desterke, Mickaël Marin, Hélène Tronchère, Cyntia Taveneau, Sokhavuth Sar, Philippe Briolotti, Soumaya Benjelloun, Abdelaziz Benjouad, Patrick Maurel, Valérie Thiers, Stéphane Bressanelli, Didier Samuel, Christian Bréchot, Ama Gassama-Diagne
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-19 (2016)
The accumulation of lipid droplets is often observed in hepatitis C virus infection, but the mechanism of their formation is not known. Here the authors show that septin 9 expression is increased in infected livers, and a septin 9/phosphatidylinosito
Externí odkaz:
https://doaj.org/article/6bbbd7beb26d487f871269821bc6ebff
Autor:
Sayeh Ezzikouri, Mohammad Enamul Hoque Kayesh, Soumaya Benjelloun, Michinori Kohara, Kyoko Tsukiyama-Kohara
Publikováno v:
Vaccines, Vol 8, Iss 2, p 216 (2020)
Despite the availability of an effective preventive vaccine for hepatitis B virus (HBV) for over 38 years, chronic HBV (CHB) infection remains a global health burden with around 257 million patients. The ideal treatment goal for CHB infection would b
Externí odkaz:
https://doaj.org/article/5e834b6ff31c43859fac73fd7c772a85
Autor:
Abdelaaziz Ouahrouch, Moha Taourirte, Joachim W. Engels, Soumaya Benjelloun, Hassan B. Lazrek
Publikováno v:
Molecules, Vol 19, Iss 3, Pp 3638-3653 (2014)
In this study, we describe the synthesis of 1,4-disustituted-1,2,3-triazolo-quinazoline ribonucleosides or acyclonucleosides by means of 1,3-dipolar cycloaddition between various O or N-alkylated propargyl-quinazoline and 1'-azido-2',3',5'-tri-O-benz
Externí odkaz:
https://doaj.org/article/74b8402f3c3e4ee6ae20232f35ea1a55
Autor:
Sayeh Ezzikouri, Rhimou Alaoui, Khadija Rebbani, Ikram Brahim, Fatima-Zohra Fakhir, Salwa Nadir, Helmut Diepolder, Salim I Khakoo, Mark Thursz, Soumaya Benjelloun
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54793 (2013)
BACKGROUND:Genetic variation in the IL28B gene has been strongly associated with treatment outcomes, spontaneous clearance and progression of the hepatitis C virus infection (HCV). The aim of the present study was to investigate the role of polymorph
Externí odkaz:
https://doaj.org/article/08f6ebe34f0448cdb5c44536d9c329f3
Autor:
Bouchra Kitab, Abdellah Essaid El Feydi, Rajaa Afifi, Christian Trepo, Mustapha Benazzouz, Wafaa Essamri, Fabien Zoulim, Isabelle Chemin, Hanane Salih Alj, Sayeh Ezzikouri, Soumaya Benjelloun
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42891 (2012)
BACKGROUND: Hepatitis B virus (HBV) is one of the most common human pathogens that cause aggressive hepatitis and advanced liver disease (AdLD), including liver cirrhosis and Hepatocellular Carcinoma. The persistence of active HBV replication and liv
Externí odkaz:
https://doaj.org/article/0fa400f1ec984b5197518bed25b3a0ce
Autor:
Soumaya Benjelloun, Yasuhito Tanaka, Mohammad Enamul Hoque Kayesh, Shuko Murakami, Pascal Pineau, Shintaro Ogawa, Haya Altawalah, Sayeh Ezzikouri, Karima Abounouh, Bouchra Kitab, Kyoko Tsukiyama-Kohara, Michinori Kohara, Hind Dehbi
Publikováno v:
Molecular Biology Reports. 49:403-412
Hepatitis B Virus (HBV) is the most common cause of chronic liver disease worldwide. The mechanisms that regulate HBV viral replication remain poorly defined. Here, we show that blocking of the neddylation elicits antiviral effect against HBV replica
Autor:
Marc P. Windisch, Soumaya Benjelloun, Jalal Nourlil, Wahiba Ezzemani, Haya Altawalah, Sayeh Ezzikouri, Anass Kettani
Publikováno v:
Infectious Disorders - Drug Targets. 21:572-581
Background:Globally, the recent outbreak of Zika virus (ZIKV) in Brazil, Asia Pacific, and other countries highlighted the unmet medical needs. Currently, there are neither effective vaccines nor therapeutics available to prevent or treat ZIKV infect
Structure-guided discovery approach identifies potential lead compounds targeting Mpro of SARS-CoV-2
Autor:
Kuldeep Dhama, Anass Kettani, Marc P. Windisch, Sayeh Ezzikouri, Jalal Nourlil, Soumaya Benjelloun, Yashpal Singh Malik, Michinori Kohara, Kyoko Tsukiyama-Kohara, Mohcine Elmessaoudi-Idrissi
Publikováno v:
VirusDisease
The ongoing coronavirus disease 19 caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become fatal for the world with affected population crossing over 25 million in more than 217 countries, consequently declared a global